Stemloop makes it easy to measure small molecules. We discover, develop, & deploy synbio-enabled biosensors to address large-scale unmet molecular data demands.
Here at Stemloop, we are excited to see improvements upon existing technologies and can’t wait to see what happens next in the cell-free biosensor space!
Read the full article here: https://t.co/FvyPLaRS68
#SyntheticBiology#CellFree#Biosensors
Stemloop Reads: ROSALIND 3.0
Earlier this week, an article from @LucksLab was published in Nature Chemical Biology. This research expands upon ROSALIND, the technology that powers Stemloop’s biosensors, to become more sensitive using a new technology.
The result: Using this method, the authors developed new sensors for the antibiotic tetracycline and zinc. These sensors showed limit of detection (LoD) improvements of 10-fold over the previous iteration of ROSALIND.
🧬Biosensor History
Curious about how transcription factor based biosensors came to be? A recent article from Brecht De Paepe and Marjan De Mey in ACS Synthetic Biology details key milestones in the development of these sensors.
The article ends with a review of the existing tools that can support the further development of biosensors. They also include tools that are currently developing that may support further innovations, such as artificial intelligence (AI).
At Stemloop, we’re passionate about harnessing the power of RNA to develop innovative tools. This research brings us closer to impactful solutions for real-world problems.
📖Read more here: https://t.co/sgdoVKIiIc
#SyntheticBiology#RNA#Innovation#PointOfCareTesting#CRISPR
Stemloop Reads: CRISPR-Based Diagnostics
Last week, ACS Synthetic Biology published an article co-authored by several Stemloop scientists! This work showcases the development of a CRISPR-based point-of-care diagnostic tool, demonstrated as a SARS-CoV-2 test.
The model successfully predicted results outside the initial dataset, and the final test demonstrated a limit of detection range in the hundreds of attomolar range!
Whoever says the government doesn't move fast hasn't met the DARPA BTO team led by @mkoeris! 🚀
Last week, @StemloopInc was invited to pitch @DARPA’s Biological Technologies Office for a catalytic, SAME DAY award to support breakthrough technologies…
How can AI accelerate the bioeconomy?
@StemloopInc@BiochemPhD@LucksLab
are transforming biosensor design for health and the environment with a new effort supported by
@DARPA@INVOatNU
https://t.co/1cqOh54rK9
🌟Exciting news!🌟
Last week, Stemloop was awarded funding from DARPA’s Artificial Intelligence (AI) and Biotechnology initiative to enable machine learning (ML) for biosensors.
With this award, we are well-positioned to revolutionize how we measure and monitor the small molecules in our world. “DARPA’s support is a significant step forward in our journey to unlock the power of biology to sense and respond to the world’s challenges,” said Alam.