https://t.co/QXzXEIrrbb We found that for women who develop a short cervix (all comers), cerclage, pessary, & vaginal progesterone were equally efficacious at preventing PTB. I really think we need to be more discerning in who receives & benefits from these interventions.
https://t.co/xJbrfdsoE6 Placental diffusion-relaxation reveals significant changes in the placenta prior to preterm birth….. Application of this technique may allow clinically valuable interrogation of histopathological changes before preterm birth and aid management.
Our biomarkers will include Actim Partus to be introduced soon (we are also developing a quantitative version with Actim) and other measures of cervical stiffness (Pregnolia). Please do retweet.
Our latest study reveals changes in the placental transcriptome linked to gastroschisis. These changes might indicate the placenta sensing fetal distress or genetic or environmental factors predisposing to gastroschisis.
AJOG Expert Review in Labor: Clinical chorioamnionitis at term: definition, pathogenesis, microbiology, diagnosis, and treatment - Laboratory diagnosis of intraamniotic inflammation and intraamniotic infection https://t.co/xdarjShVy2
Our study "Perinatal & Neurodevelopmental Outcomes of Fetal Isolated Ventriculomegaly" is out in Translational Pediatrics! 📚
🔍 Highlights:
Severe ventriculomegaly increases risks.
Crucial insights for enhanced prenatal care & counselling. 🩺👶
Thanks to my co-authors, Fahimah Ali, Fiona Gurung, Srividhya Sankaran, Tomoki Arichi, Kypros H. Nicolaides, @NandaSurabhi, and @SpyrosBakalis, for their hard work! 👏
Read more: https://t.co/yGtw9Un1NU
Let's advance care for moms & babies! Thoughts? #FetalMedicine #Neurodevelopment #MaternalHealth #Research @KCLImmunoMicro@KingsCollegeLon@GSTTnhs@kingshealth@kingsmedicine@BMFMSNews
Important follow-up ALPS data with excellent editorial. The issue of antenatal steroids in late preterm deliveries remains thorny.
UK Perinatologists who want to help resolve the Q for late preterm twins, consider @Stoppit3Study
https://t.co/n9wTbMH6rH
Adrenal:body vol ratios significantly larger in fetuses who go on to deliver preterm. Adrenal volumes were not significantly larger, ? due to fulminating chorioamnionitis. Adrenal volumes: An MRI pilot study - Hall - 2024 - Acta O - Wiley Online Library https://t.co/j1AQfaPLaK
Vaginal micronized progesterone started after arrest of preterm labor (24-34 weeks) was not effective to prolong pregnancy or prevent preterm delivery in singletons. #SMFM24#PTB#progesterone https://t.co/AUvwf99y6j
This is important as screening and management v different. ?15% of cases we see. Need more than CL/FFN. The role of placental insufficiency in spontaneous preterm birth: - European Journal of Obstetrics and Gynecology and Reproductive Biology https://t.co/zO0FysvB6G