Syed S. Hasnain MD

Ophthalmologist | Porterville, CA
𝗚𝗹𝗮𝘂𝗰𝗼𝗺𝗮 𝗺𝗮𝘆 𝗻𝗼𝘁 𝗯𝗲 𝗮𝗻 𝗼𝗽𝘁𝗶𝗰 𝗻𝗲𝘂𝗿𝗼𝗽𝗮𝘁𝗵𝘆, 𝗯𝘂𝘁 𝗮𝗻 𝗼𝗽𝘁𝗶𝗰 𝗱𝗶𝘀𝗰 𝗮𝘅𝗼𝘁𝗼𝗺𝘆

[Syed S. Hasnain MD @SyedHasnainMD]

Every massive shift in scientific history started exactly like this: a single, dissenting voice challenging an established paradigm #glaucoma #ophthalmology #optometry

[Syed S. Hasnain MD @SyedHasnainMD]

Glaucoma may not be an optic neuropathy, but an optic disc axotomy. #glaucoma #ophthalmology #optometry

[Syed S. Hasnain MD @SyedHasnainMD]

Glaucomatous field defects, RNFL thinning, splinter hemorrhages at the disc margin, and the end-stage histology of the glaucomatous disc devoid of nerve fibers suggest that the nerve fibers along with the vasculature are being severed in glaucoma #glaucoma #ophthalmology #optometry

[Syed S. Hasnain MD @SyedHasnainMD]

Left-eye fundus of 48 y/o male with advanced glaucoma. Note the nasal shifting of blood vessels due to the unequal severance of nerve fibers #glaucoma #ophthalmology #optometry

[Syed S. Hasnain MD @SyedHasnainMD]

Left-eye fundus of 48 y/o male with advanced glaucoma. Prominent scleral edge due to RNFL thinning as a result of the severance (axotomy) of nerve fibers at the scleral edge #glaucoma #ophthalmology #optometry

[Syed S. Hasnain MD @SyedHasnainMD]

Glaucoma may not be an optic neuropathy, but an optic disc axotomy #glaucoma #ophthalmology #optometry

[Syed S. Hasnain MD @SyedHasnainMD]

Right eye of 37 year-old male with advanced glaucoma.

Notable observations:

- Prominent scleral edge (Hasnain sign) due to thinning of the retinal nerve fiber layer (RFNL), resulting from the AXOTOMY of nerve fibers.

- Sinking of the entire lamina cribrosa resulting in stretching and the axotomy of nerve fibers at the scleral edge.

- Absence of smaller vasculature (baldness) around the optic disc resulting from their severance (Hasnain sign).

Bottom Line: Chronic glaucoma may not be an optic neuropathy, but an optic disc axotomy #glaucoma #ophthalmology #optometry

[Syed S. Hasnain MD @SyedHasnainMD]

Right eye of 37 year-old male with advanced glaucoma.

Notable observations:

- Prominent scleral edge (Hasnain sign) due to thinning of the retinal nerve fiber layer (RFNL), resulting from the AXOTOMY of nerve fibers.

- Sinking of the entire lamina cribrosa resulting in stretching and the axotomy of nerve fibers at the scleral edge.

- Absence of smaller vasculature (baldness) around the optic disc resulting from their severance (Hasnain sign).

Bottom Line: Chronic glaucoma may not be an optic neuropathy, but an optic disc axotomy #glaucoma #ophthalmology #optometry

[Syed S. Hasnain MD @SyedHasnainMD]

Schematic (cross-sectional) view of the retinal nerve fibers after being severed at the scleral edge due to sinking of the lamina cribrosa occurring in chronic glaucoma #glaucoma #ophthalmology #optometry