@simroux_virus Nice!! Is the new GTDB-based db downloaded by default with "iphop download --db_dir path_to_iPHoP_db", or do you need to do something else to get that? Is it the one called "iPHoP_db_Aug23_rw"?
Thanks, Simon π
Alright, admitted, I was intimidated by twitter's name change, and haven't been online before now. But since then, this happened!!! Big congrats to @SarahCamara94#dav604 and @rafapinilla92 uncovering these unbelievable RNA based anti-#CRISPR s
Such a pleasure talking with @JacquesHughes about our findings. Big thanks to the @NaturePodcast team for having me!
Tune in to the episode to hear our conversationπ¦ ποΈ
https://t.co/l63hltJohr
Dr. Evelien Adriaenssens wrote this beautiful opinion piece about our recent baby virus study. She is the chair of the bacteriophage subcommittee within the ICTV, so her opinion matters. And I'm humbled to say the least.
@COPSAC_com@JPI_HDHL#phage
We found hundreds of viral families in baby diapers. Everything we found is online (https://t.co/Ewm8JnZ4wh). This project started all the way back in 2016. So excited that it's finally out!
@COPSAC_com@JPI_HDHL#OpenScience#phage#CRISPR#virome#metagenome
Out now: Expanding known viral diversity in the healthy infant gut
By Shiraz Shah, Ling Deng, Dennis Nielsen & colleagues.
@tcrispr@COPSAC_com
https://t.co/W8sgp1dSz2
@TCrispr lays out his brilliant paper on phages in childrens gut. I remember once thinking "Wow, we identified a handful of new viral families!". Shiraz and the rest of this group just found +100 new ones π€― Check out the brilliant online overview π
https://t.co/h6ub48sC3d
1/n
Excited to share a story on prokaryotic Argonautes (pAgos)!! π
Here, we describe a short pAgo that mediates robust antiviral protection!π‘οΈ But how!? π§΅π
https://t.co/U5KfN9NPv4
Another defence system, guys:
https://t.co/68BHZS0bjq
The prokaryotic argonaute recognises viruses using a guide RNA, then activates a transmembrane protein to depolarise the membrain and commit suicide.
#antiviral#antiphage#archaea#CRISPR
Very excited to see our story online in @NAR_Open!π
We found plasmids in nature carry a fascinating diversity of CRISPR-Casππ€―
We characterized their abundance, diversity, distribution & investigated their CRISPR contents to infer their function(s)!!
https://t.co/QHKvPXtMae