Our new study found that higher plasma pentosidine, an advanced glycation end-product marker, was associated with lower muscle mass, SPPB scores, and phase angles in community-dwelling older adults, suggesting a link between glycation stress and muscle health in later life.
Our new study found that the dietary inflammatory index (DII) was associated with periodontal inflamed surface area (PISA) in community-dwelling older adults. More pro-inflammatory diets were linked to greater periodontal inflammation, showing diet may help maintain oral health.
Our new study published in @maturitas_j found that social isolation, but not living alone, among community-dwelling older adults was associated with higher cardiovascular mortality risk (HR 2.2). Assessing social interactions may help evaluate cardiovascular risk in older adults.
We examined associations of dietary habits, and activity/sedentary behaviors with fecal incontinence severity after minimally invasive colorectal cancer surgery. Higher red meat intake and <8 h/d sedentary time were associated with lower severity. Longitudinal studies are needed.
Compared sleep measures by wrist-worn Silmee W22 and waist-worn MTN-221 against portable EEG. Silmee W22 overestimated total sleep time by 35 min and sleep efficiency by 8.1%, whereas MTN-221 overestimated them by only 3 min and 1.0%. Both misclassify quiet wakefulness as sleep.
Our new paper used machine learning to compare seven oral hypofunction components. Tongue pressure, masticatory function, occlusal force, and tongue–lip motor function were most important for identifying frailty and sarcopenia, supporting their use in simplified assessments.
Published a co-authored paper examining smartphone-measured trunk acceleration during the sit-to-stand movement to identify sarcopenia and frailty. The final model showed good accuracy for sarcopenia (AUC 0.78), supporting its potential use in large-scale functional screening.
Our hypothesis-generating study in Eur Geriatr Med examined links between blood/urine cell-free DNA (cfDNA) and sarcopenia. cfDNA showed inter-individual variability, with no differences by sarcopenia status. Plasma cfDNA was moderately correlated with muscle mass.
Our paper in @IntJObesity showed the predictive validity of sarcopenic obesity based on Asian-specific JWGSO criteria. JWGSO-defined sarcopenic obesity was associated with poorer physical function, mobility limitations, and higher mortality risk.
Our paper in Clin Interv Aging (@DovePress) shows that older adults who produce equol, a metabolite of soy isoflavones, are less likely to be frail. This provides new insights into the gut environment in healthy ageing. Longitudinal studies are needed to clarify this association.