superman

Software Developer

[Kantala fc @ifOnlyKantala]

Press and hold, see the magic

[Keith Siau @drkeithsiau]

This was a real case from Germany.

A surgeon accidentally cut his left hand with a scalpel while removing a malignant abdominal tumour called a fibrous histiocytoma.

Five months later, a new tumour appeared at the site of the surgeon’s injured hand. Molecular testing confirmed the impossible: the surgeon had developed the same type of tumour as the patient.

Histopathological and DNA analyses showed the tumour to be genetically identical to the patient’s original cancer, indicating direct implantation of tumour cells into the wound.

The surgeon’s tumour was successfully removed. Two years later, he remained well, with no evidence of recurrence or spread.

With sharps injuries, we worry about blood-borne infections. But in exceptionally rare cases, cancer cells can also seed and implant into the wound.

📽️: Zack D Films

[superman @TPTM]

@bbmhlanga @amnesty_zim Sjava makes good music

[✧˚ @Kinngszn]

Nevrine

[Wolf of X @WolfofX]

In July 2000, two teenagers stood in the same place at the same time in Qingdao, China.

They were complete strangers.

Both were visiting May Fourth Square with their families. One posed for a photo in front of the city's famous May Wind sculpture. The other happened to walk through the background, unaware that he had just become part of a memory that wasn't his.

Then life carried them in different directions.

Eleven years later, they met by chance in another city. They fell in love, got married, and eventually welcomed twin daughters into their family.

It wasn't until 2018, while looking through old family photo albums, that the husband suddenly stopped at one picture.

There he was.

A teenager in the background of his wife's vacation photo, captured years before they had ever spoken a single word to each other.

He later found the photograph taken of him that same day, confirming they had unknowingly shared the same moment long before they shared a life

[superman @TPTM]

@TatzJustice @iam_ghostzw @bla_bidza Definitely. And clearly his is not 1.5 mil. What he stands and advocates for is his price.

[superman @TPTM]

@CrimeWatchZW Very soon she will be driving a G-Wagon

[Dr. Priyam Bordoloi @DocPriyamMD]

Rates of colon cancer in young adults are skyrocketing globally. Science points to one massive DIETARY culprit driving this deadly trend.
​What is the biggest proven risk factor?

A) Artificial sweeteners
B) Ultra-processed meats
C) Seed oils
D) High-fructose corn syrup

[Dr. Priyam Bordoloi @DocPriyamMD]

THE ANSWER: B) Ultra-processed meats

The WHO classifies processed meats (bacon, hot dogs, salami) as Group 1 Carcinogens: the same evidence tier as tobacco! Here is the exact pathophysiology:

1. Nitrosamine Mutation: Added nitrates and nitrites hit your acidic gut and convert into Nitrosamines, which directly mutate and damage your colon lining's DNA.

2. Heme Catalyst: Natural Heme iron in the meat acts as a catalyst, rapidly accelerating this toxic reaction.

3. High-Heat Carcinogens: Smoking or high-temp cooking creates HCAs and PAHs: two more known carcinogens that shred cellular barriers.

The Takeaway: Risk is dose-dependent (~18% increase per 50g daily). A rare hot dog is fine....but daily deli meat is playing with fire. Swap the processed junk for high-fiber, real food!

FOLLOW ME for more such posts!

[superman @TPTM]

@Ahsan_dawar @DocPriyamMD Thanks for the information

[Afshine Emrani MD FACC @afshineemrani]

I'm a cardiologist. I need to explain something that's about to change medicine more than any drug in history — and I'm going to make it so simple a teenager can understand it.
Right now, if you have Type 1 diabetes, you inject insulin every day for life. If you take Ozempic, you inject it every week for life. If you use peptides for recovery, you inject them constantly. Stop the injections, the benefits disappear.
Every one of these treatments works brilliantly. And every one has the same fundamental limitation: you're renting the molecule. The moment you stop paying, you lose it.
What if instead of renting, you could install the factory?
That's cell therapy. And it just produced the most stunning clinical result I've seen all year.
Vertex Pharmaceuticals took stem cells, transformed them into insulin-producing islet cells in a lab, and infused them into the livers of 12 people with Type 1 diabetes — patients who had been injecting insulin multiple times daily for years or decades.
The results — published simultaneously in the New England Journal of Medicine and presented at the American Diabetes Association meeting last week:
All 12 patients restored endogenous insulin production. Their bodies were making their own insulin again — for the first time since their disease destroyed their pancreatic islet cells.
10 out of 12 — 83% — were completely insulin-independent at one year. No injections. No pumps. Their transplanted cells were sensing blood sugar in real time and producing exactly the right amount of insulin in response.
Mean reduction in daily insulin use: 92%. Zero severe hypoglycemic events after 90 days.
One procedure. Living cells. Doing what daily injections never could — responding to the body's actual needs, moment by moment, the way a healthy pancreas does.

[Dr. Priyam Bordoloi @DocPriyamMD]

STROKE at the age of 34.

​Runs 5k on weekends.
Normal blood pressure.
No diabetes. No smoking.

​But ONE common stress relief habit quietly tore a major blood vessel and caused a massive brain attack.

​A medical thread on what actually happened 👇

[Afshine Emrani MD FACC @afshineemrani]

I'm a cardiologist. If I could only recommend two supplements for the rest of my career, it would be these:

Magnesium glycinate.
Vitamin D3 with K2.

I take both every day. I prescribe both constantly. And the number of patients whose lives visibly change within weeks of starting them still surprises me after twenty years.
Up to 75% of Americans are low in magnesium. Most have no idea. If you're stressed, sleeping poorly, cramping at night, your blood pressure runs high, or you feel wired but exhausted — this is probably why.

Magnesium calms the nervous system, relaxes blood vessels, supports healthy heart rhythms, and improves sleep quality. The glycinate form is highly absorbable and gentle on the stomach. 300-400mg before bed. It's the supplement patients thank me for most — because they finally wake up feeling calm instead of wrecked.
Most Americans are also deficient in vitamin D. Low D3 quietly ruins your mood, weakens your immunity, increases inflammation, and raises cardiovascular risk. I see suboptimal levels constantly in my heart patients. Target blood levels of 50-80 ng/mL — not the bare minimum of 30 most doctors accept.

Here's what almost nobody knows: low D3 actively depletes magnesium. Your body uses magnesium to convert D3 into its active form. If you supplement D3 without magnesium, you can actually worsen a magnesium deficiency — and wonder why you still feel terrible.
You need both. They work as a system.

And always take D3 with K2. Without K2, calcium from D3 can deposit in your arteries instead of your bones. Together, they keep bones dense and arteries clean.
D3 with K2 in the morning with a meal containing fat — they're fat-soluble.
Magnesium glycinate at night before bed.

Cheap. Available everywhere. Backed by extensive evidence. And the combination addresses two of the most common deficiencies driving the fatigue, poor sleep, anxiety, muscle cramps, and low mood that millions of people are medicating with far more expensive and dangerous interventions.

Your future self will thank you. Probably within two weeks.

[Afshine Emrani MD FACC @afshineemrani]

I'm a cardiologist. A study published four days ago in Nature Medicine just proved something I've been trying to tell you on this platform for months: your body is aging faster than your parents' body did at the same age. And that accelerated aging is driving the cancer epidemic in younger adults.
WashU Medicine analyzed blood from over 164,000 people and found that those born in the 1990s show a biological age gap 92% larger than those born in the 1960s.
Same chronological age. Dramatically older biology.
And the people aging fastest had up to 15% higher risk of developing cancer before 55.
Here's the part that should change how you think about your next blood draw.

[Afshine Emrani MD FACC @afshineemrani]

I'm a cardiologist. A woman loses her husband. Two days later she's on my cath lab table — chest pain, EKG changes, enzymes elevated. Everything says heart attack.
I thread the catheter. Her arteries are pristine.
Her heart didn't clog. It shattered. From grief.
Takotsubo — broken heart syndrome. Stress hormones stun the ventricle so severely it balloons and stops pumping. 90% of cases are women. Your heart can literally break. Not a metaphor. Physiology.
But this is just one blind spot in a system built for men's hearts.
Women get microvascular disease — plaque in vessels too small for angiograms to see. Heart attacks with "clean" arteries.
Women get SCAD — leading cause of heart attack under 50. Most doctors have never diagnosed one.
Women present with fatigue, jaw pain, nausea, back pain. Medicine called these "atypical" for decades. They're not atypical. They're female-typical.
Half of humanity is not a variant.
Heart disease kills more women than every cancer combined. Fewer than half know.
Three things every woman needs to hear:
Say these exact words to your doctor: "I am concerned this could be my heart." That sentence changes everything. Don't soften it.
If tests are "normal" but symptoms persist — demand CT angiography or cardiac MRI.
If you had preeclampsia — your cardiac surveillance starts now. Not at 65.
Your heart can break from grief, from stress, from a system that wasn't built to see you.
It can also heal. If someone finally looks.
Share this with every woman you love.

[ARIPO @_ARIPO]

📢 Call for Expression of Interest

We invite qualified and experienced firms, developers, and technology partners to submit Expression of Interest for the design, development, and implementation of a comprehensive Learning Management System (LMS).

Download the Terms of Reference🔗: https://t.co/TRB131Gp0C

[Dipanshu Kushwaha @Dipanshu_AI]

🚨A man spends 50 years teaching at MIT.

He knows his time is running out.

So he records one last lecture — everything he knows, distilled into a single hour.

He died 5 months later.

This is that lecture.

The most important hour you'll watch this week. 👇
Bookmark it for later

[Dad's bible @DadsBible_]

A Father raised three sons.
All three became millionaires before the age of 35.
When he was asked how he did it,
He said:"I forbade them from one habit while they were growing up. "

[Afshine Emrani MD FACC @afshineemrani]

I'm a cardiologist. After 40, stop guessing about your health. These numbers tell you whether you're building a long, vibrant life — or quietly declining without knowing it.

I run these on myself. I run them on every patient I care about. Most are cheap bloodwork. All are available now. And together, they paint a picture no standard annual physical will ever give you. Print this. Bring it to your next appointment. Your 60-year-old self will thank you.
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𝗙𝗮𝘀𝘁𝗶𝗻𝗴 𝗜𝗻𝘀𝘂𝗹𝗶𝗻
Target: below 5 μIU/mL. Ideal: 3-4.
This is the 10-year warning bell your standard panel completely misses. Your glucose and A1c can look "normal" for a decade while your pancreas is working overtime to keep them there. Fasting insulin catches insulin resistance 5-10 years before your A1c moves. By the time A1c rises, the damage is already extensive.

𝗛𝗢𝗠𝗔-𝗜𝗥
Target: below 1.0.
Calculated from fasting insulin and fasting glucose. The single best measure of insulin sensitivity. Above 1.0 and your metabolism is already under strain. Above 2.5 and you're insulin resistant — even if every other number looks fine.

𝗛𝗯𝗔𝟭𝗰
Target: below 5.4%.
Not below 5.7% — that's the threshold where medicine calls you "prediabetic." By then you've been metabolically compromised for years. Optimal is below 5.4%. Blood sugar mastery is longevity mastery.

𝗧𝗿𝗶𝗴𝗹𝘆𝗰𝗲𝗿𝗶𝗱𝗲 : 𝗛𝗗𝗟 𝗥𝗮𝘁𝗶𝗼
Target: below 2. Ideal: below 1.
Your metabolic health crystal ball. This ratio predicts insulin resistance, cardiovascular risk, and metabolic syndrome better than any single lipid number alone. A ratio above 3.5 is a red flag regardless of what your total cholesterol says.

𝗔𝗽𝗼𝗕
Target: below 80 mg/dL for moderate risk. Below 60 for high risk.
I've written about this extensively. ApoB counts every atherogenic particle hitting your artery walls. A 2024 analysis found 54% of patients had dangerous levels that standard LDL testing completely missed. If you only know your LDL, you're driving with one eye closed.

𝗟𝗽(𝗮)
Test once in your lifetime.
100% genetic. 1 in 5 Americans are elevated. Triples heart attack risk independently of everything else on this list. Diet and exercise cannot lower it. The 2026 ACC/AHA guidelines now recommend everyone be tested. Most never have been.

𝗵𝘀-����𝗥𝗣
Target: below 1.0 mg/L.
You can have perfect cholesterol and inflamed arteries silently preparing to rupture. hs-CRP measures the fire behind the plaque. The JUPITER trial proved that finding and treating inflammation saves lives — even when lipids look fine. If this number is elevated, your mouth, your gut, your metabolic health, and your visceral fat are the first places to investigate.

𝗩𝗶𝘁𝗮𝗺𝗶𝗻 𝗗
Target: 50-80 ng/mL.
Not the bare minimum of 30 your doctor accepts. Suboptimal vitamin D is linked to higher inflammation, weaker immunity, increased cardiovascular events, worse mood, and poorer outcomes across nearly every disease I treat. Supplement D3 with K2 — without K2, calcium deposits in your arteries instead of your bones.

𝗧𝗲𝘀𝘁𝗼𝘀𝘁𝗲𝗿𝗼𝗻𝗲 (𝗧𝗼𝘁𝗮𝗹 + 𝗙𝗿𝗲𝗲)
Men: optimal range 600-1000+ ng/dL total.
Declining testosterone is an independent predictor of cardiovascular death in men. It's tied to insulin resistance, arterial stiffness, visceral fat accumulation, and systemic inflammation. DHEA-S drops 10-20% every decade after 30. Tracking these isn't about vanity — it's evaluating your body's systemic resilience.

𝗕𝗹𝗼𝗼𝗱 𝗣𝗿𝗲𝘀𝘀𝘂𝗿𝗲
Target: below 120/80. Aim closer to 110/70.
Every point above optimal is cumulative arterial damage. Buy a home cuff. Measure morning and evening, seated quietly for five minutes, arm at heart level. White-coat readings in the office miss what's really happening. The smartest $40 investment in cardiac self-care.

𝗩𝗢𝟮 𝗠𝗮𝘅
Men over 40: above 40 mL/kg/min. Women over 40: above 35.
Cardiorespiratory fitness is the single strongest predictor of all-cause mortality — stronger than smoking, diabetes, or heart disease as individual risk factors. A landmark study in JAMA found that extreme fitness was associated with the lowest mortality with no upper limit of benefit. You can estimate VO2 max with a timed mile, a rower test, or a wearable. Get faster every year.

𝗡𝘂𝗺𝗯𝗲𝗿 𝗼𝗳 𝗠𝗲𝗱𝗶𝗰𝗮𝘁𝗶𝗼𝗻𝘀
Target: as few as possible.
Every medication you're on should be earning its place. I just wrote about five commonly prescribed drugs that do more harm than good with long-term use. Bring your full medication list to every appointment. Ask: "Do I still need this?" Deprescribing is one of the most powerful and underused tools in medicine.
ꟷꟷꟷ

Thirteen numbers. Most available through cheap bloodwork and simple tests. Get them once or twice a year. Here's what I want you to understand: these numbers don't just tell you where you are. They tell you where you're heading. A fasting insulin of 8 today becomes diabetes in five years. An ApoB of 120 today becomes a heart attack in ten. An hs-CRP of 3 today means your arteries are inflamed right now — regardless of how healthy you feel. The standard annual physical checks a fraction of these. It was designed to find disease that's already there. This panel finds the disease that's coming — years before it arrives.

What gets measured gets improved. Optimize with the foundation I write about every week on this platform:
Zone 2 cardio plus resistance training 3-4 times per week. High-protein whole-food nutrition. Sleep 7-9 hours — non-negotiable. Morning sunlight. Stress management. And the targeted supplements I've covered in detail — creatine, magnesium, CoQ10, D3+K2, glycine, omega-3, psyllium husk.
The breakthroughs coming in the next decade — gene editing for cholesterol, cellular reprogramming, senolytics that clear senescent "zombie" cells driving inflammation and aging, GLP-1 drugs rewriting metabolic medicine — will be most powerful for people who've already built the metabolic foundation to receive them.

The future of medicine is personalized. But it starts with knowing your numbers today. Print this list. Book the bloodwork. Own the data. Prevention isn't passive. It's the most aggressive thing you can do for the decades ahead.