@pimentel_md Urgent cisplatin-based chemotherapy beginning today without orchiectomy. If HCG is massively elevated, many centers would give 3 days of EP and hold for a bit and resume with 5 day course once bleeding risk is past. I council such patients that they may end up in ICU intubated
JCO Comments and Controversies piece out. Provides rationale for PRESTIGE and MAGESTIC trials to come.
Thanks @UroAlsyouf@siadaneshmand@LuciaNappi4
DOI: 10.1200/JCO.22.02002
@siadaneshmand is stepping out on me with different organ! However, per usual, he's making high-level, multi-front impacts on management of the bladder cancer as well as TC. Congrats on a memorable AUA and keep up the good work
Case for pRPLND as chemo-sparing approach in CSII NS becoming stronger. @moosemousa@RHamiltonUrol#AUA2023 PRIMARY RETROPERITONEAL LYMPH NODE DISSECTION FOR METASTATIC NONSEMINOMATOUS GERM CELL TUMOR:
@LuciaNappi4 ASCO presentation of long f/u BCC pilot will be a forme fruste of S1823 which will also be presented in the Trials in Progress session as well. @SupportingSWOG
Testis cancer oral abstracts ASCO pick up nicely on two emerging likely practice changing themes. miR371 (@LuciaNappi4) and primary RPLND in early regional seminoma (T. Tandstad). Can't wait
Well. . . This is a bit awkward. ChatGPT appears to be as good at poetry as it is at understanding clinical trial design, conduct, actual patient impact and cogent debate
While not a lot of new information, the article is important in that it reiterates the high baseline of CVD risk factors (with or without cisplatin) for men as they move into their 40s/ 50s. Should have low threshold for management of HTN, dyslipidemia, obesity, energy balance
Not ground breaking but worth reiterating. Chemo for GCT was revolutionary but strive to cure while minimizing exposure to it, legit long term baggage
@Testiscancer @siadaneshmand @AdityaBagrodia @drphil_urology https://t.co/XKIWGFxvf1
Nice AUA abstract by Candelas-Gomez, Hamilton, Jewett et al re Canadian 2nd opinion in GCT. Mirrors England SWENTOTECA German efforts at hub and spoke care delivery