TheArtuncLab

This is the official account of The Artunç group

[TheArtuncLab @TheArtuncLab]

Nice editorial on our recent published AMILOR study - Optimizing diuretic treatment of patients with edema and nephrotic syndrome - Hinrichs - Acta Physiologica - Wiley Online Library https://t.co/nwYY9mEb8z

[TheArtuncLab @TheArtuncLab]

We are proud to present our latest clinical pilot study - Amiloride versus furosemide for the treatment of edema in patients with nephrotic syndrome: A pilot study (AMILOR) - Schork - Acta Physiologica - Wiley Online Library https://t.co/MasBTabKuh

[HCKH_Hamburg @HCKH_Hamburg]

Reconceptualizing our understanding of the kidney slit diaphragm: Nephrin and Neph1 molecules form a highly complex, cross-interacting fishnet structure. Check out this preprint involving @HCKH member Florian Grahammer: https://t.co/n7mF0bbNf8

[TheArtuncLab @TheArtuncLab]

Two cases of severe vitamin D3 intoxication treated with therapeutic plasma exchange and high cut-off hemodialysis
#VitaminD, #VitaminDIntoxication, #VitaminDToxicity, #supplements
https://t.co/2nxmmZHPTH

[TheArtuncLab @TheArtuncLab]

Plasminogen deficiency does not prevent sodium retention in a genetic mouse model of experimental nephrotic syndrome https://t.co/6ZnhlDzCT3… The role of the uPA-Plg System in proteolytic ENaC activation-different model, different Knock-out...same result?! #proteasuria

[TheArtuncLab @TheArtuncLab]

Good news! Our article received enough citations to be a #topcitedarticle in its journal

[TheArtuncLab @TheArtuncLab]

Frontiers | Editorial: Rising stars in red blood cell physiology: 2022 https://t.co/2aI4FO1cjZ

[TheArtuncLab @TheArtuncLab]

Proteolytic activity against the distal polybasic tract of the gamma subunit of the epithelial sodium channel ENaC in nephrotic urine https://t.co/FU347VgDyq

[Pflugers Archiv - European Journal of Physiology @PflugersArchiv]

Is prostasin involved in ENaC-mediated sodium retention of experimental nephrotic syndrome? Find out here 👉 @uni_tue #ENaC #Nephron #OpenAccess https://t.co/UuNfL8e6by

[TheArtuncLab @TheArtuncLab]

Nice summary on our last years work - Rodent models to study sodium retention in experimental nephrotic syndrome https://t.co/U8USJX2uIO

[Pflugers Archiv - European Journal of Physiology @PflugersArchiv]

During nephrotic syndrome, ENaC leads to renal sodium retention. This is however independent of the activation of prostasin expressed at similar loci, as shown by @DanielEssigke et al. @uni_tue @NIDCR #kidney #openaccess https://t.co/TJgZLkpO1n

[TheArtuncLab @TheArtuncLab]

Nice commentary by Per Svenningsen about Sodium retention in the #nephroticsyndrome and the non-enzymatic function of #prostasin | SpringerLink @PflugersArchiv https://t.co/nySqS3GF8Q

[TheArtuncLab @TheArtuncLab]

Proud to add another piece of the puzzle to understanding proteolytic ENaC activation - Zymogen‐locked mutant prostasin (Prss8) leads to incomplete proteolytic activation of ENaC and severely compromises triamterene tolerance in mice @ENaC_paper https://t.co/57Vi5GcrI1

[TheArtuncLab @TheArtuncLab]

More about Prss8 and it’s role in proteolytic #ENaC activation under nephrotic conditions by @TheArtuncLab @DanielEssigke now published @PflugersArchiv https://t.co/aBVJW1Ra6F https://t.co/jLUrsnNycx

[TheArtuncLab @TheArtuncLab]

79-year-old female patient with nephrotic-range #proteinuria - read more in the Mediquiz in the Deutsche Medizinische Wochenschrift #DMW https://t.co/zLsm0dFIS9

[TheArtuncLab @TheArtuncLab]

The authors reply https://t.co/2DvploHftg

[TheArtuncLab @TheArtuncLab]

Nice commentary on our recent paper @Kidney_Int by Bissinger et al. @TheArtuncLab - Role of proteinuria in the anemia of chronic kidney disease https://t.co/hMqw3WFnhq

[TheArtuncLab @TheArtuncLab]

Anemia and red blood cell deformability in proteinuric chronic kidney disease - Kidney International https://t.co/RI4ehR0tIN

[TheArtuncLab @TheArtuncLab]

Organ Donation From a Brain Dead Donor With Vaccine-induced ... : Transplantation https://t.co/wYpFRWiIBf

[Pflugers Archiv - European Journal of Physiology @PflugersArchiv]

Factor VII activating protease (FSAP) as candidate for proteolytic activation of the epithelial sodium channel (ENaC). More on this in nephrotic mice right here 👉 @uktuebingen #NephroticSyndrome #Physiology #OpenAccess https://t.co/fIYxpuDdNP

[Pflugers Archiv - European Journal of Physiology @PflugersArchiv]

Serin protease cleave the extracellular domain of #ENaC's to change open probability -> a commentary by @MikeAlthausHBRS and Lawong. @h_bonnrheinsieg #ionchannel #epithelial #cysticfibrosis #proteolysis #ENaC https://t.co/awt1IJFvdn

[TheArtuncLab @TheArtuncLab]

And refer to the nice commentary by @MikeAlthausHBRS & R.Y. Lawong published beforehand @PflugersArchiv https://t.co/vmKALMni4e

[TheArtuncLab @TheArtuncLab]

One more protease activating #ENaC in vitro - #FSAP. We are proud to share our recently published work about #FSAP and it’s clinical relevance in #proteasuria.
@PflugersArchiv https://t.co/MmYe9dwyJ7