Open position for a research assistant/PhD student to work in metabolic and transcriptional regulation of stem cells in Drosophila! Check out more at https://t.co/YgGDM45E1r
Interested in doing your PhD in Lisbon, working in neurodevelopment and Drosophila?
Our group is looking for candidates to apply for a FCT PhD fellowship! See below for more info and visit our group's page at https://t.co/3QOXHjOY0f.
Repost appreciated!
#DBfeature#Drosophila🪰
Opposing effects of ecdysone signaling regulate neuroblast proliferation to ensure coordination of brain and organism development
by Andreia Oliveira, Catarina Homem @TheHomemLab
https://t.co/723tes10of
In our latest article we demonstrate that Drosophila brain development is under the coordination of the hormone ecdysone. We show that neuroblasts have an intrinsic capacity to proliferate indefinitely and require ecdysone signalling to determine cell cycle pace!
Do you know how animals coordinate the growth of their different organs during development? Systemic signals such as hormones coordinate the development of all organs and direct tissue specific developmental programs.
Serine hydroxymethyl transferase is required for optic lobe neuroepithelia development in Drosophila
An #OpenAccess Research Article in our Stem Cells and Regeneration section of #DevSImetabolism by Eunice Silva, @margarida_venda & @TheHomemLab
https://t.co/5muR0KBPQr
In our brand-new article in @PLOSBiology we use Drosophila to show that the transcription and translation of neurotransmitter-associated genes is timely coordinated with the animal’s development.
Within hours of #neuron birth, terminal differentiation genes are transcribed, but not translated. In #PLOSBiology, @TheHomemLab reveals that these transcripts are only translated days later in a way that coordinates with developmental stage in #Drosophila
https://t.co/j1fcWUhEz4
Our postdoc Ana just signed her CEEC contract, granting her funds to pursue her scientific work for the next 6 years! Congrats ! @nova_medschool@fct_pt@NOVAunl
Check-out our new paper! Serine hydroxymethyl transferase (Shmt) is required for optic lobe neuroepithelia development in Drosophila.
https://t.co/B2EDYvKJ3y
These defects are similar to the defects that are observed when neural tube closure defects occur in human fetuses, and sets important foundations to understand how folic acid works during brain formation.
Check out our newest open-access paper on dMyc-dependent upregulation of heterodimeric amino acid transporters and their role in Drosophila brain tumor growth!
https://t.co/3j03jij4Uv
Interestingly, we show that the oncogene dMyc is involved in the upregulation of these transporters, highlighting the important link between oncogenes and metabolic transporters in the regulation of tumor growth.