Catarina Homem

[Catarina Homem @TheHomemLab]

Open position for a research assistant/PhD student to work in metabolic and transcriptional regulation of stem cells in Drosophila! Check out more at https://t.co/YgGDM45E1r

[Catarina Homem @TheHomemLab]

Interested in doing your PhD in Lisbon, working in neurodevelopment and Drosophila?

Our group is looking for candidates to apply for a FCT PhD fellowship! See below for more info and visit our group's page at https://t.co/3QOXHjOY0f.

Repost appreciated!

[Developmental Biology @Dev_Bio_Journal]

#DBfeature #Drosophila🪰

Opposing effects of ecdysone signaling regulate neuroblast proliferation to ensure coordination of brain and organism development

by Andreia Oliveira, Catarina Homem @TheHomemLab
https://t.co/723tes10of

[Catarina Homem @TheHomemLab]

In our latest article we demonstrate that Drosophila brain development is under the coordination of the hormone ecdysone. We show that neuroblasts have an intrinsic capacity to proliferate indefinitely and require ecdysone signalling to determine cell cycle pace!

[Catarina Homem @TheHomemLab]

Our latest article is out ! read it here👇
https://t.co/8IY5i3ASPs

[Catarina Homem @TheHomemLab]

Do you know how animals coordinate the growth of their different organs during development? Systemic signals such as hormones coordinate the development of all organs and direct tissue specific developmental programs.

[FocalPlane @focalplane_jcs]

Happy #FluorescenceFriday! Eunice Silva, @margarida_venda & @TheHomemLab find that serine hydroxymethyl transferase is required for optic lobe neuroepithelia development in Drosophila.
📖@Dev_Journal: https://t.co/9d5eBc5y3F
#DevSImetabolism

[Development @Dev_journal]

Serine hydroxymethyl transferase is required for optic lobe neuroepithelia development in Drosophila

An #OpenAccess Research Article in our Stem Cells and Regeneration section of #DevSImetabolism by Eunice Silva, @margarida_venda & @TheHomemLab

https://t.co/5muR0KBPQr

[Catarina Homem @TheHomemLab]

According to our model, the onset of translation is delayed in order to regulate neuronal maturation.

Learn more by checking the link in our bio!

[Catarina Homem @TheHomemLab]

Our latest article is out ! read it here👇
https://t.co/90Ao7tTmv8

[Catarina Homem @TheHomemLab]

In our brand-new article in @PLOSBiology we use Drosophila to show that the transcription and translation of neurotransmitter-associated genes is timely coordinated with the animal’s development.

[PLOS Biology @PLOSBiology]

Within hours of #neuron birth, terminal differentiation genes are transcribed, but not translated. In #PLOSBiology, @TheHomemLab reveals that these transcripts are only translated days later in a way that coordinates with developmental stage in #Drosophila
https://t.co/j1fcWUhEz4

[Catarina Homem @TheHomemLab]

Our postdoc Ana just signed her CEEC contract, granting her funds to pursue her scientific work for the next 6 years! Congrats ! @nova_medschool @fct_pt @NOVAunl

[Catarina Homem @TheHomemLab]

@ERC_Research @HHMINEWS @EMBO @fct_pt @nova_medschool #basicbiology #development #drosophila #metabolism #neurodevelopment

[Catarina Homem @TheHomemLab]

Check-out our new paper! Serine hydroxymethyl transferase (Shmt) is required for optic lobe neuroepithelia development in Drosophila.
https://t.co/B2EDYvKJ3y

[Catarina Homem @TheHomemLab]

These defects are similar to the defects that are observed when neural tube closure defects occur in human fetuses, and sets important foundations to understand how folic acid works during brain formation.

[Catarina Homem @TheHomemLab]

@ERC_Research @HHMINEWS @EMBO @fct_pt @nova_medschool #basicbiology #CancerResearch #drosophila

[Catarina Homem @TheHomemLab]

Check out our newest open-access paper on dMyc-dependent upregulation of heterodimeric amino acid transporters and their role in Drosophila brain tumor growth!

https://t.co/3j03jij4Uv

[Catarina Homem @TheHomemLab]

Interestingly, we show that the oncogene dMyc is involved in the upregulation of these transporters, highlighting the important link between oncogenes and metabolic transporters in the regulation of tumor growth.