(student-run acct) Bioinorganic physical chemistry @emorychem. Life is a movie, so we make movies to show the dynamics of metalloenzymes #PhoTonsOfFun.
Emory University researchers have repurposed enzymes to produce diazo compounds from hydrazones under milder, greener conditions than traditional chemical methods. https://t.co/VRQ3ZUelzI
KFB Lab Alert: Our first report on chemoenzymatic diazo synthesis enabled by VHPO-mediated hydrazone oxidation is now available @J_A_C_S! Congratulations to @ManiksharmaASR for leading this effort and @The_Davis_Lab for another awesome collaboration!
https://t.co/BW5gfQTlk0
Research Highlight now online:
Intermolecular 1,2,4-thiadiazole synthesis by @PSeavill
https://t.co/1InovbZpNv ($)
Highlighting the @J_A_C_S article by Katherine Davis, Kyle Biegasiewicz & co-workers @The_Davis_Lab@KFBChem
Our exploration of the fascinating enzymes behind thio/selenoimidazole antioxidant biosynthesis continues! Dive into the details here:
https://t.co/hsjHvkCDM6
Thrilled to share our preprint from an exciting collaboration with the Seyedsayamdost and Greene labs on non-canonical cytochrome P450s, including an X-ray crystal structure of the first known natively Ser-ligated P450!
https://t.co/BfIpDZ7rsB
KFB Lab Alert: Congratulations to @ManiksharmaASR, @PascoeCam, and Stacey K. Jones on completing our first efforts toward using enzymatic halide recycling for intermolecular heterocycle synthesis. An awesome collaboration with @The_Davis_Lab!
https://t.co/5u6QroVBQq
The Mo Lab discovers a new selenometabolite and confirms a selenometabolome in @NatureChem: “Discovery of the selenium-containing antioxidant ovoselenol derived from convergent evolution.”
Congrats Chase, Vanessa, Mo and colleagues @EmoryChem: https://t.co/vvfzUVOiVY
Long-time member/friend of #ACSDBC@BookerMan_PSU has always been at the forefront of enzyme mechanism research from radical SAMs to iron-sulfur clusters. He's also worked tirelessly to support the #biochem community through service and mentoring young scientists. #BlackinChem
Se can be incorporated into natural products, but little is known about the biosynthetic machinery involved.
@The_Davis_Lab and colleagues now structurally characterize the first known Se-glycosyltransferase and selenosugar synthase.
https://t.co/fdvFLwMLhv
#biosynthesis