Theonie

Founding President, Prologue Medicines; Sr Principal @FlagshipPioneer; Cofounder and ex-Chief Innovation Officer @Alltrna.

[Theonie @theonie]

Excited to highlight Karan Tandon in our #PeopleofPrologue series! It has been a joy to watch him grow as he works to unlock new learnings and optimize our platform.

If you have a passion for scientific innovation, check out our open roles here: https://t.co/DIfjdEn1PN

[Prologue Medicines @Prologue_Med]

Meet Karan Tandon, associate scientist and our next feature in our #PeopleofPrologue series. We spoke with him about his background in protein science and automation, and what excites him about his work at Prologue. #LifeAtPrologue #WeAreHiring #JoinUs

[Theonie @theonie]

Thank you to my fellow Emerging Leaders panelists @fasengelhardt and Theresa Tribble for the inspiring discussion on innovation and leadership in life sciences and I look forward to continuing our conversations!

[Theonie @theonie]

Ahead of this year’s @BosBusinessJournal’s Women Who Lead in Life Sciences event, I got to talk with @hannah_reports about my path to exploring the boundaries of biology at @FlagshipPioneer, @Prologue_Med, and @alltrna.
https://t.co/rvxGr6gJkr

[Theonie @theonie]

We’re thrilled to introduce @Prologue_Med to the world. Congratulations to our entire team on this significant achievement!

[Prologue Medicines @Prologue_Med]

We're excited to announce our launch as Prologue Medicines.

As a @FlagshipPioneer company, we're unlocking the therapeutic potential of the viral proteome for the creation of powerful new medicines. Learn more: https://t.co/OwBgNa3bFJ
#FlagshipFounded

[Prologue Medicines @Prologue_Med]

We're excited to announce our launch as Prologue Medicines.

As a @FlagshipPioneer company, we're unlocking the therapeutic potential of the viral proteome for the creation of powerful new medicines. Learn more: https://t.co/OwBgNa3bFJ
#FlagshipFounded

[Theonie @theonie]

It was great to share more about Alltrna’s #AI enabled platform and how we’ve leveraged it to significantly improve the therapeutic properties of #tRNA through optimizing sequence and chemical modifications.

Listen to the @AlldusAI #AIinAction #podcast to learn more!

[Alldus International @AlldusAI]

In ep. 490 of #AIinAction, @alltrna's Theonie Anastassiadis & Stephen Eichhorn discuss how Alltrna are harnessing #tRNA #biology for therapeutic #medicines, examples of how their work will improve treatment for patients & more

🎧 Listen Now 👇👇👇

https://t.co/SYdOiZBSvT

[The Nobel Prize @NobelPrize]

BREAKING NEWS
The 2023 #NobelPrize in Physiology or Medicine has been awarded to Katalin Karikó and Drew Weissman for their discoveries concerning nucleoside base modifications that enabled the development of effective mRNA vaccines against COVID-19.

[Theonie @theonie]

🙌Thrilled to spotlight Ki-Jana Carter, our talented Machine Learning Scientist. His journey from physics to #tRNAtherapeutics shows the interdisciplinary power that fuels our innovation!

If you lead & work with focus & passion, see our open positions: https://t.co/hdlj0Kiwt4

[Alltrna @alltrna]

We are excited to share this quarter’s #EmployeeSpotlight featuring Ki-Jana Carter, Machine Learning Scientist. The thread 🧵below explores what drew him to Alltrna and what excites him about #tRNA.

[Theonie @theonie]

I am so happy that this is published – it’s been a year in the making! We are excited to review and explore how the diverse biology of #tRNA and its fragments can be transformed into scalable #geneticmedicines with unique therapeutic potential, especially for #rarediseases.

[Alltrna @alltrna]

Big week! Our review in @jbiolchem just published providing a comprehensive look at #tRNA molecules and their therapeutic potential: https://t.co/GsjcwjeNAJ

And we spoke with the @TheScientistLLC about being on the cusp of viable #tRNAmedicines: https://t.co/AUVklyOCW7!

[Theonie @theonie]

Thanks @DrugTargetRev for the opportunity to share my career story and thoughts about creating inclusive and supportive environments for #WomenInSTEM.

[Alltrna @alltrna]

Our cofounder and Chief Innovation Officer @theonie was featured in @DrugTargetRev’s monthly #WomenInSTEM series, which showcases and celebrates the achievements of inspiring women in the field and shares advice for those considering #CareersInSTEM.

https://t.co/5e65T73FyZ

[Theonie @theonie]

How is #tRNA different from #mRNA?  What is #StopCodonDisease?  Anne Pariser and I explain this and more in this feature.

[Flagship Pioneering @FlagshipPioneer]

What if we could rethink the approach of classifying patients by their individual mutated gene or a traditionally defined clinical presentation and instead classify patients based on their shared genetic mutations? #Flagshipfounded @alltrna shares more: https://t.co/eeYTUGNwxa

[Flagship Pioneering @FlagshipPioneer]

What if we could rethink the approach of classifying patients by their individual mutated gene or a traditionally defined clinical presentation and instead classify patients based on their shared genetic mutations? #Flagshipfounded @alltrna shares more: https://t.co/eeYTUGNwxa

[Theonie @theonie]

Congrats Will and welcome to the team Chris. I’m very excited to work with you both and the rest of the team as we unlock the power of #tRNA and transform medicine!

#WeAreAlltrna #StopCodonDisease

[Alltrna @alltrna]

We are excited to welcome Chris Henderson as our new Chief Scientific Officer and give a big congrats to Will Kiesman on his promotion to Chief Technology Officer. Together, we are transforming #tRNA biology into powerful #programmablemedicines!

https://t.co/1H6eRxoaqL

[Alltrna @alltrna]

We are excited to welcome Chris Henderson as our new Chief Scientific Officer and give a big congrats to Will Kiesman on his promotion to Chief Technology Officer. Together, we are transforming #tRNA biology into powerful #programmablemedicines!

https://t.co/1H6eRxoaqL

[Theonie @theonie]

So excited to share a big milestone for Alltrna – our Series B financing! This will support continued scaling of our platform and advancing our first #tRNA medicines towards the clinic. Congrats to our amazing team for such a great accomplishment!

[Alltrna @alltrna]

We’re thrilled to announce our Series B financing of $109 million with a world-class group of investors. We look forward to advancing our first #tRNA medicines to clinical trials and building a new future for patients with #StopCodonDisease.

https://t.co/TKxgIJb4vb

[Theonie @theonie]

Excited for the team to have a break this July! As we live our core values of patient-centric innovation, this time off fuels our passion to create groundbreaking tRNA medicines. We’ve returned energized and inspired to transform medicine for patients everywhere!

[Alltrna @alltrna]

At Alltrna, we believe that a well-deserved break fosters creativity and rejuvenation. That's why we had company-wide #summervacation at the beginning of July. We know that our commitment to patients is best fulfilled when we take care of ourselves as well.

#WeAreAlltrna

[Theonie @theonie]

We love Derrick’s passion for quality and drive to explore the unknown! Our team is bold and thoughtful in their work, understanding that patients deserve better. If you consider yourself a scientific explorer & team builder, check out our #openpositions: https://t.co/hdlj0Kiwt4

[Alltrna @alltrna]

We are excited to share this quarter’s #EmployeeSpotlight featuring Derrick Allen, Senior Scientist I. The thread 🧵below explores what he does at Alltrna as a member of the CMC team.

[Theonie @theonie]

I had such a great time volunteering with our team!

[Alltrna @alltrna]

This month, employees volunteered at @c2cboston and @communityserv as part of our annual day of service. Giving back to the community is one way we live our values. We give it our all, every day – in and outside the office! #WeAreAlltrna.

[Theonie @theonie]

Thanks @ Jonathan D. Grinstein, PhD, for the chat and for highlighting our first presentations of data. This article does a great job of explaining #tRNAbiology and what sets Alltrna apart!

[Alltrna @alltrna]

Thanks @GrinsteinJ for taking with us about the first data demonstrating the power of Alltrna’s platform presented at #ASGCT23 and #TIDESUSA. This @GENbio article gives a great overview of how we can design and deliver #tRNAmedicines in #StopCodonDisease.

https://t.co/X9TrCH1kjn

[Theonie @theonie]

I’m looking forward to presenting these data at #ASGCT23! Our platform uniquely harnesses the combinatorial potential of #tRNA sequences and modifications to engineer tRNAs with improved potency and activity for in vivo readthrough of premature termination codons.
#tRNAbiology

[Alltrna @alltrna]

We’re excited to share the first preclinical data demonstrating the power of Alltrna’s platform to design and deliver #tRNAmedicines that restore disrupted protein production in #StopCodonDisease.

https://t.co/S8a5OXkv2U

#tRNA #rarediseases #cancer #ASGCT23 @ASGCTherapy