Thiago J Borges, PhD

Transplant biologist and immunologist | Assistant Prof @MGHSurgery @mgh_transplant @HarvardMed. Tweets are my own

[Thiago J Borges, PhD @ThiagoJBorges]

🐷➡️🧬 In the first pig-to-human kidney transplant, a multiomics approach demonstrated that persistent innate immune activation (monocytes/macrophages) remains a key barrier. Better control of innate immunity will be critical for future success.

[Nature Medicine @NatureMedicine]

High-dimensional immune profiling of a living recipient of a pig-to-human #xenotransplant provides insight into the immune landscape of #xenotransplantation and directions for improved #immunosuppression strategies.
https://t.co/JlMV93nWrU

[Leonardo V. Riella @LVRiella]

Incredible opportunity to lead our Living Donor Kidney Transplant Program @mgh_transplant
Join a collaborative, high-volume team (>240 tx/year) with real momentum in innovation and program growth (tolerance/xeno)
Know someone great or interested yourself:
https://t.co/nmz2bj9ury

[Thiago J Borges, PhD @ThiagoJBorges]

Looking forward to speak at the @AST_COTS Guest Symposium at the #IMMUNOLOGY2026™ @ImmunologyAAI with @ValeriaMas11

[AST Community of Transplant Scientists @AST_COTS]

COTS Guest Symposium at IMMUNOLOGY2026™ in Boston April 17, 2026 8:00–9:30 AM : The Immunology of Xenotransplantation
Moderators: Dr. Anita Chong, Dr. Thiago J. Borges
Speakers: Drs. David K. C. Cooper, Valeria Mas, Thiago J. Borges, Brendan Keating
https://t.co/YrSY0xeo9x

[Ayman Al Jurdi, MD FASN @AlJurdi]

We’re very excited to be hosting the first Glomerular Disease Conference in Boston on May 30th!

Join us to learn what’s new in glomerular diseases from world-class experts.

In-person and virtual options available.

Fellows/trainees can attend for free. DM for details.

[Thiago J Borges, PhD @ThiagoJBorges]

Check out our latest paper @amjtransplant 👇🏼👇🏼

[American Journal of Transplantation @amjtransplant]

🚨 Editor’s Choice 🚨
"Best practices in mouse models of skin transplantation," by Borges et al
https://t.co/nxsysPzvxt
#SkinTransplantation #TransplantResearch #MouseModels

[Leonardo V. Riella @LVRiella]

Historic moment in transplant medicine. Tim, our @mgh_transplant xenotransplant patient, who previously received a gene-edited pig kidney and was off dialysis for 9 months, has now received a human kidney. A new chapter in care and hope. https://t.co/Y5TwaknZVr

[Thiago J Borges, PhD @ThiagoJBorges]

I’m very proud to have been the first Editorial Fellow on the Basic Science track @amjtransplant

This experience has been incredibly valuable for my development as a scientist. I strongly recommend this program to anyone interested in academic publishing.

[American Journal of Transplantation @amjtransplant]

American Journal of Transplantation is now accepting applications for the AJT Editorial Fellowship Program!

Work alongside journal editors. Build peer review and communication skills.

Applications open through Jan 31
https://t.co/O13k7DlLre

[Thiago J Borges, PhD @ThiagoJBorges]

A brief T–cell–mediated rejection occurred early, likely due to residual lymph node immunity, but was successfully treated. No antibody-mediated rejection was seen. @LVRiella @MassGeneralNews

[Thiago J Borges, PhD @ThiagoJBorges]

🐷➡️🧬 In the first pig-to-human kidney transplant, a multiomics approach demonstrated that persistent innate immune activation (monocytes/macrophages) remains a key barrier. Better control of innate immunity will be critical for future success.

[Nature Medicine @NatureMedicine]

High-dimensional immune profiling of a living recipient of a pig-to-human #xenotransplant provides insight into the immune landscape of #xenotransplantation and directions for improved #immunosuppression strategies.
https://t.co/JlMV93nWrU

[Leonardo V. Riella @LVRiella]

Hot off the press @NatureMedicine: We report the first high-dimensional immune profiling of a living human recipient of a gene-edited pig kidney at @MGH_Transplant / @MGBKidneys, defining the evolving human xeno-immune response over time. https://t.co/to6CdMjv9B

[Mass General Transplant @mgh_transplant]

In honor of Richard Slayman, the first pig kidney recipient, we hosted a workshop gathering global experts in xenotransplantation to explore unpublished clinical and ethical advances in kidney, heart, and liver transplantation.
#Xenotransplantation #TransplantInnovation

[Science Immunology @SciImmunology]

Scientists have found that C/EBP⍺ activates an IRF8 #enhancer, driving its expression in early myeloid progenitors and specifying type I conventional #DendriticCell lineage. @washu_pathology @JingNeticist

Read more in Science #Immunology: https://t.co/stvtqL9ZPb

[Leonardo V. Riella @LVRiella]

He’s thriving nearly 4 months after receiving a gene-edited pig kidney at @mgh_transplant @MGHSurgery @MGHKidneys @harvardmed. “He was tired of just surviving. A pig kidney gave him a shot at living.” @CNN
🔗 https://t.co/h0noI42DKc

[Thiago J Borges, PhD @ThiagoJBorges]

@LVRiella @MGHSurgery @AST_info @karinarlima @CrisBonorino

[Thiago J Borges, PhD @ThiagoJBorges]

🚨 Our new study in @SciTranslMed identified the inhibitory receptor Siglec-E as a critical brake on dendritic cell activation and T cell–mediated transplant rejection. 1/5
https://t.co/Z4FqTvFE8X

[Thiago J Borges, PhD @ThiagoJBorges]

💡 Takeaway: Innate immune checkpoints like Siglec-E/7/9 are emerging as crucial regulators of transplant rejection. 4/5

📄 Newsroom @MGBResearchNews: https://t.co/BF1iVaHTP0

[Thiago J Borges, PhD @ThiagoJBorges]

🚨 Great Opportunity! 🚨

The @LVRiella lab, @mgh_transplant, is seeking a Postdoc in Transplant Immunology with expertise in Microsurgery.

📍 Apply now! #Postdoc #Microsurgery #TransplantResearch

[Thiago J Borges, PhD @ThiagoJBorges]

🇧🇷🇧🇷🇧🇷🇧🇷

[The Academy @TheAcademy]

Brazil snags the Oscar for Best International Feature Film. Congratulations to the cast and crew of I'M STILL HERE! 🇧🇷 #Oscars

[Mass General Transplant @mgh_transplant]

🚨 Breaking Records Again! 🚨
For 13 years in a row, our transplant teams have saved more lives through #OrganTransplantation than any hospital in New England.
👏 Shoutout to our patients, care teams and researchers for an amazing year in 2024! #TransplantInnovation #DonateLife