Timothy Klein

Postdoc - Bondy-Denomy lab, UCSF. PhD - Whitney lab, McMaster University.

[Nicole Marino @Nicole_D_Marino]

My lab is almost set up, and I'm looking for great people to join it! I am currently recruiting a research technician to drive an exciting project on molecular antagonism between bacteria and phage. If you're interested, DM me or apply to this position: https://t.co/4hRh3EIiv4

[McMaster Health Sciences @machealthsci]

The Canadian Society for Chemistry has announced that @McMasterU’s @JohnWhitneyIIDR will receive its 2024 Melanie O’Neill Award.

Whitney is being honoured for his cutting-edge research into the molecular mechanisms of antibacterial toxins. @McMasterIIDR

https://t.co/Vku0eJwB2i

[Ardem Patapoutian @ardemp]

I wrote down my rules on how to Science. I hope you find it useful!

[Timothy Klein @TimothyAKlein]

Interesting and thoughtful stuff.

[Itai Yanai @ItaiYanai]

Out today in @NatureBiotech! PhD students & postdocs: there's a trick – overlooked and underused – for having new ideas in the creative process. Talk science 1 on 1 with a science buddy that you trust and think of it as an improvisation. https://t.co/Xw7VpKHot2…
@MartinJLercher

[Timothy Klein @TimothyAKlein]

@proftracypalmer @s_prakhar0 @JohnWhitneyIIDR Thank you Tracy!

[Timothy Klein @TimothyAKlein]

Please check out our latest paper on the type VIIb secretion system where we elucidate the structure and function of the LXG domain! This was work started at the end of my PhD but was bravely picked up and finished by @s_prakhar0 and the Whitney lab crew. https://t.co/WCai76bn7z

[McMaster Biochemistry & Biomedical Sciences @BBS_McMasterU]

McMaster researchers discover molecular ‘barcode’ used by bacteria to secrete toxins #BrighterWorld #McMaster https://t.co/oFB3DLJ3yB

[Timothy Klein @TimothyAKlein]

Shout out to @JohnWhitneyIIDR for all of the support offered during my PhD (and beyond). I also have to thank @McMasterIIDR and @BBS_McMasterU for being the best place to do research in Canada (my own, admittedly biased opinion).

[Timothy Klein @TimothyAKlein]

@prehnalab @MBMicrobiology @UMmicrogsa @UofmMicroclub Take good care of him!

[Timothy Klein @TimothyAKlein]

@wilbertbitter @JohnWhitneyIIDR @biorxiv_micrbio Thanks Wilbert. Yes, I spent my whole PhD thinking of the two systems as very different only for them to end up looking highly similar.

[Timothy Klein @TimothyAKlein]

I'm very excited to present the latest type VII secretion system research from the @JohnWhitneyIIDR which is out now at @biorxiv_micrbio. In this work, we look deeper into how toxins are recognized and secreted by this Gram +ve secretion system. https://t.co/mVzfZRH4Wm

[Timothy Klein @TimothyAKlein]

The @JohnWhitneyIIDR lab, @McMasterIIDR and @BBS_McMasterU were all incredibly supportive of me during not only this study but my entire PhD and so I'd like to offer thanks to the entire community for supporting this work.

[Timothy Klein @TimothyAKlein]

The study was a major team effort that required several talented young scientists to finish. In particular, @s_prakhar0 started working on this project with me as an undergraduate researcher and really pushed it forward when I left the lab.

[Global Nexus @MacGlobalNexus]

Congratulations to @Dr_Lori_Burrows and @JohnWhitneyIIDR, who will receive @CSMB_SCBM investigator awards this week. Both Burrows and Whitney are being recognized for their important research into disease-causing bacteria. | @machealthsci @McMasterIIDR

https://t.co/37LJUAsMpB

[Joe Bondy-Denomy @joeBondyDenomy]

Years ago, we wrote a proposal about using phage anti-defense genes to discover new defense systems. The idea was to take advantage of anti-defense gene clustering (islands) to ask what the neighbors of known anti-RM/CRISPR genes are inhibiting. 1/5
https://t.co/FTIzsySViW

[John Whitney @JohnWhitneyIIDR]

Physician in training by day, alarmone biochemist by night – Congrats to @MacBiochemGrad alumnus Sheri Ahmad!
Enzymes that specifically hydrolyze (p)ppApp.
https://t.co/3GEw4ojZ8V

[McMaster Biochemistry Graduate Program @MacBiochemGrad]

Congrats to the 2022 Biochem Grad Program Impact Award Winners!

E. Shepherdson for their paper in PNAS
https://t.co/kErcaWKPSO

M. D’Agostino for their co-authored paper in Cell
https://t.co/J1WI5AvecT

N. Bullen for their paper in Molecular Cell
https://t.co/Ybp5JxCHNc

[bioRxiv Microbiology @biorxiv_micrbio]

A novel variant of the Listeria monocytogenes type VII secretion system EssC component is associated with an Rhs toxin https://t.co/KvPrK82VOu #biorxiv_micrbio

[Erin Huiting @ErinHuiting]

Our latest CBASS story from the @joeBondyDenomy lab has arrived! 🙌Through a serendipitous collaboration with Yue Feng's lab, we uncovered an anti-CBASS protein that ‘sponges’ up a broad spectrum of cyclic dinucleotides.

https://t.co/Me72kD0YHy

1/14

[Timothy Klein @TimothyAKlein]

@HaleyZubyk @Assembler_AG Now send her to USA for ye old postdoc.