Timothy Stiles

Building the world's most modern, open source, software library for genetic engineering.

[Timothy Stiles @TimothyStiles]

Dear everyone,

LOOK AT WHAT GITHUB JUST ANNOUNCED.

[GitHub @github]

Announcing the inaugural cohort of the GitHub Accelerator: 20 projects embarking on a 10-week journey to build a sustainable funding model. https://t.co/QYdsH0Terk

[Wei Shen 沈 伟 @shenwei356]

Looks useful. Poly project from @TimothyStiles has a Golang pkg 'seqhash' (https://t.co/673EmMdRLZ) as well, and seqkit has a 'sum' cmd for the whole fasta/q file, both supporting circular/linear, single/double-stranded seqs (https://t.co/mtxOrd30Jh).
https://t.co/Tlg6C0BdVA

[Timothy Stiles @TimothyStiles]

@fisher_ke Oooo I like this one.

[Timothy Stiles @TimothyStiles]

To all my friends in town for synbiobeta:

Love y'all and want to see your faces but I'm sick and don't want to give y'all conference cough 😷

[Timothy Stiles @TimothyStiles]

I want to hire this kid.

[Timothy Stiles @TimothyStiles]

Meme driven development

[Timothy Stiles @TimothyStiles]

Depends on how fast I can do the live demo but the talk I gave at synbiobeta the other year averaged out to a rate of 1 unique SpongeBob meme appearing every 18.75 seconds.

[Arye Lipman @aryelipman]

@TimothyStiles @PracheeAC @AsteraInstitute @koeng101 how many spongebob memes will be featured in said talk

[Timothy Stiles @TimothyStiles]

@aryelipman @PracheeAC @AsteraInstitute @koeng101 Looks fun. Just submitted a talk proposal.

[Timothy Stiles @TimothyStiles]

@genius_eu @GPrime85 @Harada_TEKKEN Waffle House Index and natural disasters should be worked into the map somehow.

[Timothy Stiles @TimothyStiles]

@TylerMaran It's incremental but it's definitely an improvement.

[Timothy Stiles @TimothyStiles]

Thinking about making a local meetup in SF called, "Anything but Beer, Pizza, and AI", because it's getting dismal out here folks.

[Timothy Stiles @TimothyStiles]

I remember the first meetup I ever went to in the Bay Area had steak, mezcal, a DJ, and a dude who figured out how to run windows 98 in the browser via web assembly showing off for 150 nerds.

We used to be a community, a proper community.

[Timothy Stiles @TimothyStiles]

Thinking about making a local meetup in SF called, "Anything but Beer, Pizza, and AI", because it's getting dismal out here folks.

[Timothy Stiles @TimothyStiles]

tired: longevity research

wired:

[Timothy Stiles @TimothyStiles]

Feels like there should be a regression test for this.

[Kieran Samuk @ksamuk]

PSA, since I've now seen problems arising from this: As of Sept 2023, GATK no longer makes missing genotypes explicit in VCFs (i.e. "./." as in the VCF spec). Missing genotypes are instead coded as "0/0" with a DP=0 format field. See attached for examples.

[Timothy Stiles @TimothyStiles]

@cool_scootre proud of you

[Timothy Stiles @TimothyStiles]

Do it with @ollama

I've got llama2 running on a 16gb macbook air right now and the most difficult part of setup was waiting for the model to download.

[Tyler Maran @TylerMaran]

are LLMs going to drive a swing back to on prem?

i'm looking at $970/mo on AWS for the equivalent compute of my 16gb macbook

seriously thinking of just buying two more macbooks and running omni from my living room

[Timothy Stiles @TimothyStiles]

annnd @ollama built with absolutely 0 errors on the first try with CGo which if you've used CGo before you know is impressive.

[Timothy Stiles @TimothyStiles]

There was a certain 𝒋𝒆 𝒏𝒆 𝒔𝒂𝒊𝒔 𝒒𝒖𝒐𝒊 to this event hosted by @ollama and @replicate tonight that made it feel really special.

Never have I been so excited to go home after an event and build something with CGo.

[ollama @ollama]

Super excited for tonight’s Local & open-source AI developer meetup!!

[Timothy Stiles @TimothyStiles]

@Colonellucas27 u can do it I believe in u

[Timothy Stiles @TimothyStiles]

everytime I see a code coverage badge above 90% on a git repo I get an unreasonable feeling of joy

[Timothy Stiles @TimothyStiles]

in awe of the size of this lad. what to do with this electric motor?

lime for scale.