Debbie Toiber

Molecular Biologist, DNA repair, sirtuins, ageing and Neurodegeneration

[Debbie Toiber @ToiberDebbie]

Genluminati, a novel, is free for 3 days! https://t.co/KRcYK07bx6

[Debbie Toiber @ToiberDebbie]

https://t.co/FwDtwu9aO6

[Debbie Toiber @ToiberDebbie]

Why'd you have to go and make things so complicated? Simplicity as a Lens: A New Way to Model Brain Aging. https://t.co/fzBVbI4uKu our latest preprint! #AgingResearch #Neuroscience #Alzheimers #SIRT6 #biotech

[Debbie Toiber @ToiberDebbie]

Congratulations to Yuval, the leading author, and all our collaborators: Dmitrii Smirnov, Songchen Yang, Daniel Stein, Zeev Slobodnik,
@EremenkoEkater2
Shai Kaluski-Kopach, Monica Einav, and Ekaterina Khrameeva

[Debbie Toiber @ToiberDebbie]

Congratulations to Yuval, the leading author, and all our collaborators: Dmitrii Smirnov, Songchen Yang, Daniel Stein, Zeev Slobodnik, @EremenkoEkater2 Shai Kaluski-Kopach, Monica Einav, and Ekaterina Khrameeva

[Debbie Toiber @ToiberDebbie]

Why'd you have to go and make things so complicated?

Simplicity as a Lens: A New Way to Model Brain Aging.
https://t.co/FwDtwu9aO6
See our latest preprint!
#AgingResearch #Neuroscience #Alzheimers #SIRT6 #BioTech

[Debbie Toiber @ToiberDebbie]

SIRT6 Regulates Protein Synthesis and Folding Through Nucleolar Remodeling - Stein - 2026 - Aging Cell - Wiley Online Library https://t.co/D7NTbR8fF9

[Literary Titan @LiteraryTitan]

Genluminati follows a group of young scientists who invent a DNA-based religion as a cynical experiment—only to lose control of it when belief spreads, and a prophet emerges. Did the concept begin as #satire for you, or did you always see it turning dark?
https://t.co/Oa44sVZwM1

[Debbie Toiber @ToiberDebbie]

Check out this book recommendation from Literary_Titan: https://t.co/ICBmmxz38O via @Bookbub

[Ben-Gurion University of the Negev @bengurionu]

🟠 For the full article>>
https://t.co/PeTzCsJYO6

[Debbie Toiber @ToiberDebbie]

This positions SIRT6 as a critical, upstream drug target for combating neurodegenerative pathology.
Amazing work by Shai Kaluski-Kopatch, and collaborators

[Debbie Toiber @ToiberDebbie]

SIRT6 decline throws Off Mood, Sleep, and Cognition.
https://t.co/3NSXGGoisF
Tryptophan byproducts build proteins, NAD+, and neurotransmitters (serotonin and melatonin). Yet, in aging and neurological disease, this balance is lost, leading to impaired mood, learning, and sleep.

[Debbie Toiber @ToiberDebbie]

Crucially, we show that this damage isn't permanent. By inhibiting the enzyme TDO2 in our SIRT6 knockout fly model, we were able to significantly reverse both neuromotor decline and vacuolar formation, indicating a powerful therapeutic window.

[Debbie Toiber @ToiberDebbie]

@BarakRotblat just in case someone wants to join: https://t.co/KRcYK07bx6

[Barak Rotblat @BarakRotblat]

what am I up to? reading @ToiberDebbie 's new book of course

[Debbie Toiber @ToiberDebbie]

@BarakRotblat Are you now a believer?

[Debbie Toiber @ToiberDebbie]

@CharlesMBrenner 🤷‍♀️😁

[Debbie Toiber @ToiberDebbie]

They turn it into a social experiment, testing people’s faith. The book explores their lives as PhD students doing research and as the masterminds behind a new religion, delving into moral and ethical dilemmas when things spiral out of control. Paperback https://t.co/FkFCciN1X8

[Debbie Toiber @ToiberDebbie]

GENLUMINATI is now available!

In this work of fiction, a group of university friends studying biology becomes obsessed with the idea of creating a religion based on “reading your own genome to achieve enlightenment.”

Kindle https://t.co/57QOA65QYK