Antonio Aquino

BUILDING & THINKING

[Antonio Aquino @TonesTokens]

@RealShahir @elonmusk 100%. What’s sad is everyone will continue to attack you “for siding with the attacker” when in no case or point did any of your talking points derive that. There’s a large class of racism waking back up and being sold to everyone.

[Antonio Aquino @TonesTokens]

@DaazP47590 @NicHulscher Not trying to be funny but I was scratching my ass as I read this. We’re all fucked.

[Antonio Aquino @TonesTokens]

@elonmusk Miss this Elon.

[barney @barneyxbt]

let me make sure i’m understanding this correctly

the supreme court is refunding all tariff money back to corporations.

the same corporations that didn’t pay a single cent of those tariffs to begin with.

they passed every dollar directly to you through higher prices on everything you buy

you went to the store and paid more for groceries. you paid more for clothes. for car parts. for literally everything.

that money came out of YOUR pocket not theirs

and now the refund goes to THEM?

the corporations who used the tariffs as an excuse to raise prices even higher than the tariff itself and pocket the difference

the american people funded the tariffs.

the corporations profited off the tariffs.

and now the corporations get a refund on money they never spent in the first place
and nobody in washington thinks the people who actually paid should get the money back.

not a single person has even suggested it

guess we are never getting our DOGE checks either

this country does not work for you.

it works for them. it’s a joke

and they’re not even pretending anymore

[Vaishnavi @_vmlops]

SOMEONE BUILT A MAP THAT SHOWS EXACTLY WHERE EVERY POWER PLANT, TRANSMISSION LINE, SUBSTATION & DATA CENTER SITS ON THE US GRID

all on one interactive map. all free

you can see how the grid is laid out... where the datacenters cluster... which transmission corridors carry the load... where the high-capacity connection points are

https://t.co/bRWJj6OA5P

zoom into any region and the whole picture comes into focus why energy costs what it costs, why data centers go where they go, why some states are power exporters and others aren't

this is the kind of infrastructure visibility that used to require expensive industry reports

now it's one tab

[Wall Street Apes @WallStreetApes]

Jamie Dimon, CEO of JPMorgan Chase, says that US Government raising taxes doesn’t do anything to help the average American

He says raising taxes does nothing because Congress just launders the money to their friends, special interest groups and “17,000 lobbying groups”

“I don't know anyone, and you guys in the room, you might be Democrats, Republicans who thinks that sending another trillion dollars to Washington D.C will actually improve anything. So when you say raise taxes, if you said raise taxes and directly give it to the people who need it, do it. That does not happen. It goes to all these interest groups, and they give it to their friends and all that.”

“Which is why the people are considered a swamp. It's kind of a swamp, the 17,000 lobbying groups. But bank companies are guilty too. They're just fighting for their one self-interest as opposed to what's good for my country”

[Memes and Markets @Memesandmkts]

If you didn’t see what the White House just did, you need to watch this.
w/@inneroperator

[Antonio Aquino @TonesTokens]

@CountDiaz @crashoverride @Iakopo92250 @FearedBuck You should get some help; mentally. Anyways just some advice.

[Antonio Aquino @TonesTokens]

@Arnold172061 @crashoverride @Iakopo92250 @FearedBuck “WHitE KniGhts LikE YoU ArE WorSE”

someone didn’t love their momma.

[Antonio Aquino @TonesTokens]

@coffeebreak_YT Sad that intellectuals now use their mechanics for arbitrary derivatives. I remember when when plant trees for shade we’d never sit in was cool. Thank you coffee not being a sellout.

[Nick Gerli @nickgerli1]

The thing everyone gets wrong in the housing market is they think it's about mortgage rates.

When it's actually about prices.

Buyer demand is at record lows because prices (inflation-adjusted) are at record highs.

No one wants to buy a house they know it will be worth less in 3-4 years.

Meanwhile, mortgage rates around 6% is abundantly normal for the U.S. going back 100+ years.

That's why movements in mortgage rates (either up or down) aren't having any material impact on sales right now.

Meanwhile, if you manage to bring prices down meaningfully, the buyers will flood back.

[Antonio Aquino @TonesTokens]

@crashoverride @Iakopo92250 @FearedBuck Bunch of sad little men defending their “daddy” get slapped. This generation is fucking cooked.

[Antonio Aquino @TonesTokens]

@Macuahuitl67 @returntoEuro @ClavicularNews Go slob on it some more dawg. No one gives a fuck.

[Antonio Aquino @TonesTokens]

@Spanky_Boii @phrenphrenphren @TaraBull @grok Bunch of bots on here pushing rhetoric. Fucking nothing better to do with their lives. People with actual brains stand with you.

[Antonio Aquino @TonesTokens]

@TheEndOfTh86ob @reiakgae26 @MyColleagueMio2 She’s a deranged person. And a nasty ass racist.

[Felipe Demartini @namcios]

A IA ACABOU DE TORNAR O DIAGNÓSTICO DE CÂNCER 100x MAIS BARATO

Satya Nadella acaba de anunciar o GigaTIME – o modelo de IA da Microsoft que transforma uma lâmina de patologia de US$5 em um mapa molecular que antes custava milhares de dólares.

Pare e leia de novo.

A imunofluorescência multiplex (mIF) é o padrão-ouro pra entender como o sistema imunológico interage com tumores. É o que determina se a imunoterapia vai funcionar ou não.

O problema? Cada imagem custa milhares de dólares, exige equipamento especializado, e escala zero. Hospitais de países emergentes? Esquece.

Aqui está o que a Microsoft fez:

→ Treinou o modelo em 40 milhões de células com dados pareados de H&E e mIF
→ 21 canais de proteína por lâmina
→ Aplicou em 14.256 pacientes de 51 hospitais nos EUA
→ Gerou ~300.000 imagens mIF virtuais cobrindo 24 tipos de câncer e 306 subtipos
→ Descobriu 1.234 associações estatisticamente significativas entre proteínas, biomarcadores e sobrevivência

O paper foi publicado na Cell. Open-source no Hugging Face.

Uma lâmina H&E de US$5 – a mesma que qualquer hospital do mundo já tem nos seus arquivos – agora carrega informação molecular que antes exigia laboratórios de US$500 mil.

As implicações de segunda ordem:

→ Triagem de imunoterapia em escala populacional, sem mIF real
→ Aceleração brutal de clinical trials, análise em horas, não meses
→ Hospitais no Brasil, Índia, África passam a ter acesso ao mesmo nível de análise tumoral que o Memorial Sloan Kettering

Isso é o maior nivelamento de acesso à medicina de precisão da história.

[Mario Nawfal @MarioNawfal]

🇮🇱 Polymarket gamblers threatened to KILL a journalist if he didn't change his missile strike report.

$14 million had been wagered on whether Iran struck Israel on March 10th. His report said YES. They needed him to say NO.

Death threats. WhatsApp messages at midnight. Fake screenshots. Someone posing as a lawyer. Threats against his family.

"After you make us lose $900,000 we will invest no less than that to finish you."

Prediction markets were supposed to be the future of information.

Turns out they can also make reporting the news a dangerous proposition.

Source: Times of Israel

[Tomás Vendel @vendel_tomas]

🚨 Si hoy estuviste desconectado, te perdiste algo bastante loco.

En las últimas 12 horas pasó todo esto:

- El CEO de una empresa de $200.000 millones dijo frente a cámara que el 35% de los recién graduados no va a conseguir trabajo en los próximos años. Lo dijo como si fuera completamente normal.

- Meta ganó $165.000 millones el año pasado… y aun así despidió a 15.000 personas. Al parecer, tener ganancias récord ya no es suficiente.

- Un tipo en Florida vendió su casa en 5 días usando ChatGPT.
Sin agente inmobiliario.
Sin comisión.
Sin experiencia.
Solo una laptop y una suscripción de $20.

- Un hombre en Australia usó IA para diseñar una vacuna personalizada y salvar a su perro después de que varios veterinarios le dijeran que no había nada más que hacer.

- El fundador de Uber, después de cambiar la industria del taxi en todo el mundo, ahora está construyendo robots.

- Tinder quiere acceso a tu galería de fotos: selfies borradas, fotos borracho, notas de las 3AM. Lo llaman “vibe check”.

- Naval, uno de los inversores en software más exitosos de Silicon Valley, dijo algo que dejó a muchos incómodos:

“El software está muerto.”

Cuatro palabras y toda la industria se puso nerviosa.

- Y Anthropic acaba de eliminar el límite de cuánto puede pensar su IA… y además duplicó el uso para todos.

Porque cuando el producto es lo suficientemente poderoso, primero te dejan probar más… y después ya no podés vivir sin él.

Todo esto pasó HOY.

No este mes.
No esta semana.

Hoy. Un sábado cualquiera de marzo.

Y algunos todavía creen que el mundo está cambiando lento.

[China pulse 🇨🇳 @Eng_china5]

A leaked audio recording of Elliott Brandt, CEO of the American Israel Public Affairs Committee (AIPAC), has surfaced online. In the recording, he identifies Marco Rubio (current Secretary of State), Michael Waltz (current U.S. Ambassador to the United Nations), and John Ratcliffe (current Director of the CIA) as actual Israeli agents during an informal meeting in Washington.

Brandt describes them as "lifelines" for Israeli/Jewish interests.

[MartyParty @martypartymusic]

1) The world is breaking apart.

Multiple reserve currencies. Multipolar.
More sanctions.

2) People are moving.

Technology facilitating migration.
War and conflict.
Political divides.

3) Agentic Finance

The biggest disruption since the internet. Autonomous global economies.

Demand for borderless, transportable, permissionless value is only going exponential.

Bank money is becoming useless. Tradfi is redundant.

Bitcoin supply is fixed. Solana and SUI can support magnitudes of Agentic Finance without borders or centralized authorities.

You do the math.

Turn on your DCAs. ☝️