Toronto 3D Knowledge Synthesis and Clinical Trials

A nutritional research unit affiliated with a university teaching hospital in downtown Toronto, Ontario.

[Meaghan Kavanagh MSc PhD @MeaghanKavanag1]

📢 New study alert!
Heard of the Portfolio Diet? It’s a dietary pattern designed to lower cholesterol—and now, we show it may help lower your risk of dying from cardiovascular disease.
Let’s break down the highlights from our @BMCMedicine study ⬇️
🔗 https://t.co/sOmkzFlrdi

[BMC Medicine @BMCMedicine]

Examination of the association of the Portfolio dietary pattern with cardiovascular disease mortality in a racially diverse cohort.
Read the full study here by @MeaghanKavanag1 @AndreaGlennRD and colleagues here: https://t.co/vXM2cdmcZF

[Meaghan Kavanagh MSc PhD @MeaghanKavanag1]

Check out this editorial by some of our lab members.
@Toronto_3D_Unit
Non-nutritive Sweeteners and Health: Reconciling Evidence and Interrogating Guideline Disconnects - Advances in Nutrition https://t.co/Xj1ISwL5qc

[U of T Nutritional Sciences @nutrisci_uoft]

Dr. Laura Chiavaroli’s lab study provides evidence for heart health and menopausal symptom relief in postmenopausal women considering soy!
@uoftmedicine
Read more: https://t.co/vssRhRwUGm
#SoyScience #HeartHealth #Postmenopause

[eClinicalMedicine – The Lancet Discovery Science @eClinicalMed]

Effect of digital health apps with or without gamification on physical activity and cardiometabolic risk factors: a SRMA of RCTs

#Gamification features in #healthapps may help support adults in achieving their physical activity & weight management goals

https://t.co/bh1FOFtPu1

[Meaghan Kavanagh MSc PhD @MeaghanKavanag1]

*New SRMA publication from our lab*
Soy🫛 isoflavones do not exhibit estrogenic effects compared to non-isoflavone controls in PM women.
Data from 40 RCTs with certainty of evidence high-to-moderate for all outcomes. @Toronto_3D_Unit @nutrisci_uoft
https://t.co/XR5U7vtMDu

[Meaghan Kavanagh MSc PhD @MeaghanKavanag1]

Can gamification 🎮🎯🏆be used to support behaviour change and health 🍎🏃⚖️ in adults? Well 36 trials later ....our SMRA is now published in @eClinicalMed 🙌. @steph_nishi @Toronto_3D_Unit
https://t.co/i50wFFqtJh #BCT #lifestylemed #Science #mhealth #Gamification

[BMC Medicine @BMCMedicine]

M. N. Erlich, D. Ghidanac, S. Blanco Mejia and colleagues investigate the impact on cardiometabolic outcomes of replacing soy milk for cow's milk
Read the full study here: https://t.co/H5GsDcJNzS
@Toronto_3D_Unit.

[Toronto 3D Knowledge Synthesis and Clinical Trials @Toronto_3D_Unit]

The user-friendly clinical-Portfolio Diet Score is associated with diet intake and reductions in LDL-cholesterol! See our latest work in @FrontiersIn by @MeaghanKavanag1, @AndreaGlennRD, @DrCMarinangeli and colleagues  https://t.co/Wq0vLJod7G

[CCS @SCC_CCS]

With a new year upon us, many Canadians are giving consideration to what to eat to improve their health in 2024. Help your patients lower their cholesterol and risk of #heartdisease with this updated Portfolio Diet KT tool! Learn more: https://t.co/46BvryPq9Q

[Andrea J. Glenn, PhD, RD @AndreaGlennRD]

🚨🚨🚨

We updated the #portfoliodiet infographic! Now includes healthy #MUFA oils.
🥜🌰🌱🫒🫘🫛🍓🫐🍎

Full infographic here:
https://t.co/OYnRmgQSay

[Andrea J. Glenn, PhD, RD @AndreaGlennRD]

Our new paper is out in @CircAHA today!

We examined the portfolio diet with CVD in the NHS I&II and HPFS cohorts. The diet was associated with a 14% lower risk of CVD, CHD, & stroke.

Paper: https://t.co/QtdceVOIKz

🧵👇

[Toronto 3D Knowledge Synthesis and Clinical Trials @Toronto_3D_Unit]

Read about our concerns with the WHO guidelines on non-sugar sweeteners https://t.co/z6czMMY0oF
1) reliance on prospective cohort studies which have serious limitations 2) rigorous substitution and change analyses show benefits of non-sugar sweeteners

[Toronto 3D Knowledge Synthesis and Clinical Trials @Toronto_3D_Unit]

Rescue a trial to save animals, people, the planet 🌎🫶🌱🥛
https://t.co/i8itDM3sH9
We are raising support for the STEM (Soy Treatment Evaluation for Metabolic health) trial. Click the link for details!

[Steph Nishi PhD, RD @steph_nishi]

Thanks to @JordiSalasSalva @NanBabio @paz_graniel @nutrihumana_URV @universitatURV @URVmedicina @IISPereVirgili @CIBER_OBN @CIBER_ESP @nuconep @Toronto_3D_Unit @H4HInitiative + all other authors, associations, mentors, & study participants for supporting this work.

[CPD U of T @uoftcpd]

🌎🌿 Join us for the new @uoftmedicine Environmental Lecture Series.

Over the course of 8 lectures freely open to the public, we hope to encourage dialogue and achieve positive change.

👉 Learn more: https://t.co/LS429QSgs8

🔗 Register: https://t.co/5yCroCNE1v

[Nutrients MDPI @Nutrients_MDPI]

#mdpinutrients Recommend this Latest Paper by Dr. John L. Sievenpiper et al. @Toronto_3D_Unit
👉https://t.co/tUqkfR5sVL

[Toronto 3D Knowledge Synthesis and Clinical Trials @Toronto_3D_Unit]

Check out the newly published STOP Sugars NOW Trial Protocol: a #sugar-sweetened beverage replacement trial with non-nutritive sweetened (diet) beverages or water in healthy overweight adults. Keep an eye out for the upcoming results! https://t.co/fWnxQyyIwx

[Toronto 3D Knowledge Synthesis and Clinical Trials @Toronto_3D_Unit]

New research from @UofT shows that adopting a combination of low-risk lifestyle behaviors, including healthy bodyweight, healthy diet, regular exercise, and smoking cessation can lead to 80 percent lower risk of type 2 diabetes #type2diabetesprevention https://t.co/kooVJP6wtp

[Toronto 3D Knowledge Synthesis and Clinical Trials @Toronto_3D_Unit]

All three meta-analyses strongly support that NNS is not associated with cardiometabolic harm and can be used as a replacement strategy to reduce risk from intake of empty calories from SSBs #HarmReduction #NNS #LCS #healthylifestyle

[Toronto 3D Knowledge Synthesis and Clinical Trials @Toronto_3D_Unit]

Two of our recently published systematic reviews and meta-analyses of both cohort studies https://t.co/C9BUMARUJ6 and RCTs https://t.co/aQlZHkKHOB that used rigorous methods to protect against such bias are in line with the results of this new study focusing on acute trials.