Our paper on the baseline neutrophil-to-eosinophil ratio and response to nivo/ipi in patients with mRCC is out now! @VUMC_Cancer, @VUMCHemOnc, @DukeCancer, @DukeGuCancer#kidneycancer, #biomarkers https://t.co/imRJTcZxFR 1/8
Updated IO combo table after #ASCO2023 IO/TKI presentations. VEGF tx provides early disease control while Ipi provides durability. We need a way to harness the benefits of both approaches. @montypal@DrChoueiri@tompowles1@motzermd@HHammersMD
In a month’s time, we’ve learned that CD8 T cells aren’t the only effectors of immunotherapy response: stealing the show: eosinophils @Cancer_Cell and γδ T cells @Nature out today! @NKI_nl@lab_kok@deVisserKarin@deMirandaLab https://t.co/Vy32yfG3iU https://t.co/xr2uniJpGj
1/ Happy to share👇(Tweetorial) our work on T-cell eosinophil crosstalk during immunotherapy response in breast cancer now online @Cancer_Cell A major team-effort lead by Blomberg, Spagnuolo, @hannah_c_garner, @LVoorwerk w/co-senior @deVisserKarin@NKI_nl https://t.co/5ndzMR929u
So proud of my co-fellow @YuWeiChenMD ! Merit Award, YIA, and three posters at #ASCO22 ! Look out Kidney cancer, Dr. Chen is on the scene! @VUMC_Cancer
New table highlighting results in IMDC favorable risk RCC across IO-based doublets and nivo/pembro monotx trials. Major caveats about small subsets and differing follow-up, but interesting observations emerge. Thanks to @DrChoueiri and Mike Atkins for help assembling data.
Can artificial intelligence predict outcomes with immunotherapy in NSCLC? Report @JCO_ASCO on an #AI powered spatial analysis of tumor infiltrating lymphocytes (TIL) on whole slide images to define immune phenotypes that correlate to RR and survival.
https://t.co/EVmIpm0kPE
Thanks @oncologytube for the opportunity to discuss the potential role of #ctdna within #SCLC. Shout out to @WadeIams for all his guidance and advocacy for the use of ctdna to guide treatment and improve pt outcomes
Been slow to do this. Congratulations to @VUMCHemOnc @VUMC_Cancer renal team on getting two new Department of Defense Grants to improve our biomarker analyses of renal cell cancer/therapy. @brian_rini@DrScottHaake@KimrynRathmell@katy_beckermann@YuWeiChenMD and Yu Shyr
Dr. Jaime Merchan discusses matching sequencing data with available therapies in RCC and highlights the OPTIC RCC trial lead by Dr. Brian Rini @brian_rini @VUMCHemOnc @VUMC_Cancer @ASCO#GU22
Dr. Sam Chang @UroCancerMD presents the exciting combination of IL-15 agonist (N-803) and BCG in BCG-unresponsive NMIBC @VUMC_Cancer @VUMCurology@ASCO#GU22
Adjuvant Pembrolizumab After Nephrectomy in Renal Cell Carcinoma: Embracing the Promises and Acknowledging the Uncertainties. #ASCODailyNews@ASCO https://t.co/pNXG2yFuu1