UniProt

UniProt is the central hub for the collection of functional information on proteins, with accurate, consistent and rich annotation.

[UniProt @uniprot]

UniProt is attending BSPR, Cambridge, UK.
Emily will be presenting: ‘Essential UniProt developments for proteomics: proteome resources, protein existence and PTM annotation‘ at 9.45am Tues 14th July, and teaching on the post-conference workshop.

[UniProt @uniprot]

New feature – sticky tabs and tools on UniProt pages.
No more scrolling back to the top of the page. Your navigation tabs and tools bar now follow you down the page, so your essential tools stay one click away.
Find this feature on search results, protein entry, and UniParc pages

[UniProt @uniprot]

New Protein Spotlight blog post
In this article we highlight the protein ATRX, the molecular motor that plays a key role in chromatin remodelling.

Read the blog here: https://t.co/NYEw57sokA

[UniProt @uniprot]

There’s still time to apply!
Come and join us as our UniProt Protein Function Development Team Leader, based at @EMBL-EBI in Cambridge, UK.
Apply here: https://t.co/G5S7SRVjCY
Applications close on 15th July 2026.

[UniProt @uniprot]

New large-scale methylation data for human, 1,828 sites across 1,021 proteins imported from the PTMeXchange project.
On the website and downloadable using our Proteins API proteomics/ptm endpoint.
Example: https://t.co/6fSqFdQieY

[UniProt @uniprot]

Major changes to UniProt proteomes are here!
New reference proteome selection workflow, new pan proteome workflow and downloads, and signification increases in the number of species and reference proteomes available.

See our release notes: https://t.co/kEfIvpdYeR

[UniProt @uniprot]

We have finalized major changes to UniProtKB in release 2026_02.
Now composed of reference proteome plus additional important proteins and a new collaboration with Google Deepmind.
Catch-up on all our changes: https://t.co/kEfIvpew4p

[UniProt @uniprot]

AI-generated protein annotations are expanding in UniProtKB. The new ProtNLM2 pilot dataset from @GoogleDeepMind covers 26K+ entries, predicting protein name, function, localization, keywords, and GO terms, supported by evidence-based corroboration. https://t.co/qVXyyO4bKh

[UniProt @uniprot]

Our new data release (2026_02) has just gone live and in this release headline we introduce the osmosensor TMEM63B that triggers our sense of thirst.

Read our release header for the full story: https://t.co/kEfIvpew4p

See TMEM63B entries in UniProtKB: https://t.co/fjBTJA9P9y

[UniProt @uniprot]

We’re recruiting!
Come and join us as our UniProt Protein Function Development Team Leader, based at @emblebi in Cambridge, UK.
Apply here: https://t.co/G5S7SRVjCY

Applications close on 15th July 2026.

[UniProt @uniprot]

UniProt release 2026_02 is now live!
This new UniProt data release completes the reorganization of the protein space within UniProt, and includes updates to all four resources
Read the full release notes: https://t.co/kEfIvpdYeR

[UniProt @uniprot]

UniProt Webinar reminder – Join us to learn about the proteomes resource.
Proteomes in UniProt – explore and analyse the proteome resource.
15.00 (BST) Thursday 18th June.
Registration is free but essential: https://t.co/IZ7DlaKq45

[UniProt @uniprot]

New Protein Spotlight blog post
In this article we explore how the serotonin receptor HTR2A responds to psilocybin, a hallucinogen produced by “magic mushrooms”.

Read the blog here: https://t.co/tgxSDua5mO

[UniProt @uniprot]

Big changes to UniProt proteomes are coming in our next release.
See our blog post: https://t.co/7oGRdWGt0T
For details of our new reference selection workflow: https://t.co/20qFxiuG65

[UniProt @uniprot]

New UniProt Webinar – Join us to learn about the proteomes resource.
Proteomes in UniProt – explore and analyse the proteome resource.
15.00 (BST) Thursday 18th June.
Registration is free but essential: https://t.co/IZ7DlaKq45

[UniProt @uniprot]

A new report on EMBL-EBI resources by Frontier Economics shows how tools like UniProt save time, boost productivity and support interdisciplinary collaboration.
Read the report highlights: https://t.co/CfekllziiE

[UniProt @uniprot]

Big update for SIFTS, our long-standing collaboration with @PDBeurope!

PDBe-SIFTS is now fully open-source, featuring improvements in speed and performance, and expanded compatibility for custom protein sequences and structures.
Visit PDBe-SIFTS Github: https://t.co/GcxeYjXOJ1

[Protein Data Bank @PDBeurope]

PDBe-SIFTS is now open source 🎉

Developed in collaboration with @PDBeurope and @uniprot , it enables fast, accurate residue-level mapping between protein sequences and structures, achieving >93% agreement with curated mappings.

Get started: https://t.co/hxH79eWZsy

[UniProt @uniprot]

New Homologs section
Contains Orthologs and Paralogs from the Alliance of Genome resources and cross references to multiple phylogenomic database and organism-specific databases.

See new Homologs section in APP (P05067) - https://t.co/J9sZ0706zZ

[UniProt @uniprot]

UniProt Webinar Reminder – Join us to find out what’s new on the UniProt website.

What’s new on the UniProt website: features and improvements for 2026
15.00 (BST) Thursday 14th May.
Registration is free but essential: https://t.co/fLVdz0TJwH

[UniProt @uniprot]

UniProt helps shed light on the dark proteome

The TransCODE Consortium has uncovered 1,700 new proteins that could be linked to human health. This work also reveals new protein-coding genes that are now available in UniProt.
Read the paper in Nature: https://t.co/VgExNGoJ0X