Cytopathology Cases

Twitter account for fundamental and interesting cytopathology cases seen at SUNY Upstate. Be sure to check out the fellowship here, too!

[Cytopathology Cases @UpstateCytology]

This is a case of acanthamoeba keratitis. You can read more on the CDC website here: https://t.co/XPKpZadPxg

[Cytopathology Cases @UpstateCytology]

18-year-old female presents with eye pain and blurred vision. She recently started to wear contact lenses. A corneal scraping is performed and shows the following. What is your diagnosis?

[Cytopathology Cases @UpstateCytology]

Great job & thanks for your participation! This is a case of serous carcinoma in the ovary. The patient had an elevated CA125, too. Attached are IHC stains. Keep in mind that breast cancer can also present with these 3D cannonball-like structures & vacuolization. #cytology #pathX

[Cytopathology Cases @UpstateCytology]

Ascitic fluid in a 67 yo F with a pelvic mass. Differentials? Stains? #PathTwitter #pathX #cytology #cytopathology

[Cytopathology Cases @UpstateCytology]

Thank you for participating! These are non-necrotizing granulomas. Sarcoidosis and infectious etiologies are on the differential, but don't forget the tumors that can show granulomas (eg. seminoma & Hodgkin lymphoma). Cell block & other examples are attached. #cytology

[Cytopathology Cases @UpstateCytology]

FNA of a hilar lymph node from a 40 yo female with hilar lymphadenopathy. What is pictured here? What are your differentials? #PathTwitter #cytology #cytopath #cytopathology

[Cytopathology Cases @UpstateCytology]

This is a gastrointestinal stromal tumor, which is positive for DOG-1 and CD117 (c-KIT). Differentials include a leiomyoma (SMA+) and schwannoma (S100+). Thanks for participating!

[Cytopathology Cases @UpstateCytology]

68 yo female with a submucosal lesion in the stomach. What is your differential and what stains would you order? #PathTwitter #cytopathology #cytopath

[Cytopathology Cases @UpstateCytology]

Great job, everyone! This is a carcinoid tumor, favor typical. Here are some more photos. #PathTwitter #cytopath #cytopathology

[Cytopathology Cases @UpstateCytology]

65 yo male with LLL lung mass. What is your differential? What stains do you want to order?

[Cytopathology Cases @UpstateCytology]

This is a case of HSV. There is nuclear molding, ground glass nuclear features and multinucleation.

[Cytopathology Cases @UpstateCytology]

28 year old female with a past history of bacterial vaginosis. What is your diagnosis for this cervical pap smear? #PathTwitter #cytopath #cytopathology #cytology

[Cytopathology Cases @UpstateCytology]

@nucleololailo This is a case of met. clear cell RCC. The cell block gives away some features of clear cell vs papillary RCC (fine branching vessels > fibrovascular cores). In addition, IHC can help differentiate btwn clear cell (us. CK7-, AMACR-, CAIX+) & papillary (us. CK7+, AMACR+, CAIX-)

[Cytopathology Cases @UpstateCytology]

62 year old male with hilar lymphadenopathy and flank pain. Pictured are images from an #FNA of hilar lymph node. What is your diagnosis? #PathTwitter #cytopath #cytopathology #cytology

[Cytopathology Cases @UpstateCytology]

@nucleololailo Yes! Would you like to take a stab at what type of RCC?

[Cytopathology Cases @UpstateCytology]

This is a case of HSIL. Note cells with high N:C and hyperchromatic nuclei with irregular nuclear contours. This patient also has bacterial vaginosis.

[Cytopathology Cases @UpstateCytology]

33 year old female with a past history of LSIL. What is your diagnosis for this cervical pap smear? #PathTwitter #cytopath #cytopathology #cytology

[Cytopathology Cases @UpstateCytology]

Great job! This is a case of Hashimoto (lymphocytic) thyroiditis. You can see Hurtle cells and scattered lymphocytes. Thanks for participating!

[Cytopathology Cases @UpstateCytology]

57 year old female with a high serum TSH and low serum free T4. This is an #FNA of the thyroid. What is your diagnosis? #PathTwitter #cytopath #cytopathology #cytology

[Cytopathology Cases @UpstateCytology]

@MartinFreedom8 It is an epithelial cell abnormality, but this is a case of LSIL. Kiolocytes are present here. The enlarged nuclei are about 3x that of an intermediate cell. There are other features such as irregular nuclear membranes & nuclear hyperchromasia. Thank you for your participation!

[Cytopathology Cases @UpstateCytology]

40 year old female with a negative pap history. What is your diagnosis on this cervical pap smear? #PathTwitter #cytopath #cytopathology #cytology