Urmo Võsa

Researcher at Institute of Genomics, @unitartu

[Urmo Võsa @Urmo1]

Hiring a PhD student! 🎓
PhD position on AI for predicting complex diseases using genetics, multi-omics & health records. Details and application info: https://t.co/6NbHIJbNwj

[genomicstartu @genomicstartu]

Great news! Our Associate Professor of Neuropsychiatric Genomics, Kelli Lehto, has been selected to receive the European Research Council grant!

💐Congrats on that outstanding achievement!

👉https://t.co/oVmN9UgXvn

[genomicstartu @genomicstartu]

We are looking for a PhD student!🧬

📊 Research project: The role of exposome in the development of hypertension and its interactions with genetic risk
📍 Institute of Genomics, University of Tartu
📩 Application period: 1st–15th May 2025

More info: https://t.co/NVSAVH14E2

[Marios Georgakis @MariosGeorgakis]

A great new resource for phenome-wide genetic explorations by the Estonian Biobank🇪🇪🧬

👉206,159 participants
👉GWASs for 4,884 ICD-10 diagnoses
👉2,127 unique GWAS loci
👉778 putatively novel locus-phenotype associations

[genomicstartu @genomicstartu]

New paper out: This is the largest genome-wide association study meta-analysis of its kind, analysing data on 42 female reproductive health diagnoses from the Estonian Biobank and FinnGen.

See the study in Nature Medicine: https://t.co/DqgXtIZGnO

@NatureMedicine

[Nightingale Health @NgaleHealth]

💡 New research highlight combines the data analyzed by Nightingale Health in @ESTbiobank and @uk_biobank: unlocking genetic links to metabolite traits in a groundbreaking genome-wide association study!

Researchers in a recently published pre-print have conducted a comprehensive genome-wide association study (GWAS) on 249 circulating metabolite traits in over 619,000 individuals from the Estonian and UK Biobanks. The study identified 89,489 locus-metabolite pairs, of which 4,184 are novel associations. Importantly, 12.4% of lead variants were rare, highlighting the need to study low-frequency variants in metabolic biomarker research. This resource is a major step forward in understanding genetic contributions to disease risk and drug target discovery.

Access the full preprint: https://t.co/xBBJ6Hzn2H

[Kaur Alasoo @kauralasoo]

Happy to share our most recent GWAS meta-analysis of 249 circulating metabolic biomarkers (@NgaleHealth platform) in up to 619,372 individuals.
https://t.co/61Vid5RO5m

[Erik Abner @GenomicsDoge]

📢 GWAS meta-analysis preprint:
- 249 circulating metabolite traits in over 600k individuals
- Data from UKBB & EstBB, using Nightingale NMR
- 4,184 novel loci (incl. results from non-EUR ancestries)
- Loads of low frequency variants
- Sumstats available on GWAS catalog FTP

[medRxiv @medrxivpreprint]

Genome-wide association study for circulating metabolites in 619,372 individuals https://t.co/5SXjHvU1Nu #medRxiv

[genomicstartu @genomicstartu]

The 23rd International Gene Forum 2024 will take place on September 24th – 25th, 2024 in Tartu, Estonia. The keynote speaker will be Stephen Kingsmore, president and CEO of @RadyGenomics. Read more about Gene Forum 2024 at https://t.co/14GMp11Rlf

[Lude Franke @LudeFranke]

Krista Freeman and Kaur Alasoo show in LCLs that trans-eQTLs can be highly cell-type specific. We are happy to have contributed with eQTLGen phase 2: we replicated some of these, but with much smaller effect-sizes in blood.

[Kaur Alasoo @kauralasoo]

Happy to share the latest work led by Krista Freimann in my lab. We performed the largest trans-eQTL meta-analysis in a single cell type: 3,734 LCL samples from 9 individual studies.
https://t.co/e9Vjexjnul

[Lili Milani @MilaniLili]

"While much of Europe is obsessing over this year’s European Football Championships, many Estonians — whose team didn’t qualify — are absorbed in their own genomes."

And they have pretty awesome genomes, I must say!

Read the full story by @ewencallaway:
https://t.co/UH1wtaqNeQ

[Lili Milani @MilaniLili]

We are so excited to start exploring #longread sequencing of 10,000 Estonian genomes with @PacBio
🧬improved genotype imputation reference panel
🧬more precise #pharmacogenetics
🧬actionable genetic findings for #personalizedmedicine @ESTbiobank
https://t.co/s92iLj59c8

[Lude Franke @LudeFranke]

Robert Warmerdam will present his work today on eQTLGen phase 2 at the ASHG: a full trans-eQTL meta-analysis across many blood cohorts and ancestries. Should you be interested in already working with interim freezes of eQTLGen phase 2: please get in touch with us!

[Robert Warmerdam @RobertWarmerdam]

Interested in our latest genome-wide trans-eQTL meta-analysis in the #eQTLGen Consortium?

Today, from 3-5 pm, I will be presenting interim results at #ASHG23. Interested in collaborating and joining eQTLGen? Come meet me at PB1093 or go to https://t.co/7pyhMxDePf!

[genomicstartu @genomicstartu]

🔬Excited for the 22nd Gene Forum! 🧬 Join top scientists from Europe and the USA on 24-25 Aug 2023 to discuss advances in genetics. 🌐 Among others one of the special focus will be on hereditary muscle diseases.

Read more ➡️ https://t.co/AZNeQSnKgx

[Robert Warmerdam @RobertWarmerdam]

Really exciting to have had the chance to present our newest work on eQTLGen at #ESHG2023 and having received the Fellowship of Excellence for early career scientists. Many thanks to especially @HarmJanWestra, @LudeFranke and @Urmo1 for their expertise making this work possible!

[Lude Franke @LudeFranke]

Today Robert Warmerdam at #ESHG2023 will present interim results of eQTLGen phase 2 (Clyde auditorium, 11.30 - 11.45): a genome-wide trans-eQTL analysis, with implications for many molecular QTL studies.

Interested to join eQTLGen? Get in touch or go to https://t.co/pvj5sdfZke

[Nordic Society Human Genetics/Precision Medicine @NordicPrecMed]

Attend an exciting workshop on AI & Machine Learning, co-led by:
- Anders Dale of University of California, San Diego
- Hafsteinn Einarsson of deCODE
at #NSHGPM2023 workshop on Precision Medicine: The Bridge from Research to Healthcare.

Learn more: https://t.co/UXq2Rsa1jQ