Wright Doyle Lab

Our lab is focused on discovering the causes of food allergy and eosinophilic esophagitis in order to develop new diagnostic and treatment strategies.

[Wright Doyle Lab @WrightDoyle_lab]

iEoE33 now available at the Journal of Allergy and Clinical Immunology. Congrats to Grace Pyon! https://t.co/FR1GJgPVx4
#EoE #eosinophilicesophagitis #eosinophil

[Wright Doyle Lab @WrightDoyle_lab]

EoE33 now available at the Journal of Allergy and Clinical Immunology. Congrats to Mia Masuda! https://t.co/P9hRcT5bqh
#EoE #eosinophilicesophagitis #eosinophil

[Wright Doyle Lab @WrightDoyle_lab]

Shout out to @PyonGrace who received a Distinguished Poster Presentation Award @PhxChildrens Research Day. #travelaward #eosinophilicesophagitis

[Wright Doyle Lab @WrightDoyle_lab]

@WrightDoyle_lab represents @PhxChildrens Research Day. Congrats to Adelyn Dao, Arina Putikova, and Grace Pyon for their excellent poster presentations on #eosinophilicesophagitis.

[Wright Doyle Lab @WrightDoyle_lab]

Thanks to @moisesvm for sharing his personal journey and to the @nytimes for bringing more attention to #eosinophilicesophagitis. #EoE #eosinophil

[Moises Velasquez-Manoff @moisesvm]

This happened to me. My latest in @nytmag https://t.co/5r2Otazt4D

[Wright Doyle Lab @WrightDoyle_lab]

Props to Adelyn Dao for her superb poster presentation at the Mayo Clinic Summer Undergraduate Research Fellowship (SURF) Program! #alfredsarmy #EoE #eosinophilicesophagitis

[Paneez Khoury, MD (she/her) @KhouryMD]

.⁦@wrightbenl⁩ and ⁦@WrightDoyle_lab⁩ doing some “damage” one mouse #eosinophil at a time! #IES2023 ⁦@EosinophilSoc⁩

[Wright Doyle Lab @WrightDoyle_lab]

Getting on our soapbox to sound the alarm about detergents and allergies: https://t.co/Oe18mPB2Xf

#allergy #EoE #eosinophilicesophagitis #foodallergy #asthma #atopicdermatitis #contactdermatitis

[Wright Doyle Lab @WrightDoyle_lab]

Congrats to Mia Masuda on her recently published work revealing increased food-specific IgG4 throughout the upper GI tract in #eosinophilicesophagitis (#EoE)!
https://t.co/gIyaVb4Q6u

[Wright Doyle Lab @WrightDoyle_lab]

It's a privilege to work with Arizona's pollen expert! Check out the pollen counting program at Mayo Clinic Arizona.
https://t.co/TXQeawAhqe

[SIAF @SIAF_UZH]

An editorial entitled “ Detergent-induced eosinophilic inflammation in the esophagus: A key evidence for the Epithelial Barrier Theory ” with the contributions of #SIAF members.
https://t.co/iBK1DnG0W1

#SIAF #asthma #allergy #immunology #davos #theory #Detergent #pollution

[CURED Foundation @curedfoundation]

Sodium dodecyl sulfate (#SDS) in detergents and toothpaste disrupt the epithelial barrier and prometes tissue #eosinophilia and may predispose to #eoe #AAAAI23

[Wright Doyle Lab @WrightDoyle_lab]

Congratulations to @PyonGrace, @jessicab_gibson, and @arina_evna001 for their excellent presentations at the 2022 Arizona Physiological Society Meeting.

[Wright Doyle Lab @WrightDoyle_lab]

Dr. Doyle pays tribute to early science mentors at MDI Biological Laboratory.
https://t.co/M8MnsXG0ze

[Wright Doyle Lab @WrightDoyle_lab]

Congrats to Mia Masuda on her first author publication in CTG! #Eosinophil peroxidase staining enhances the diagnostic utility of the Cytosponge in #eosinophilicesophagitis... : Clinical and Translational Gastroenterology https://t.co/RNvXyUdM7Y

[Wright Doyle Lab @WrightDoyle_lab]

Check out our detergent EoE story - should be quicker than brushing your teeth.
https://t.co/9j7nARrGKb
#eosinophil, #eosinophilicesophagitis, #allergy, #foodallergy, #EoE

[Healio Allergy and Asthma @HealioAllergy]

IL-33 expression in cells increased after six hours of treatment with 5,000 ng/mL and 10,000 ng/mL of sodium dodecyl sulfate, said researchers at @MayoClinic, indicating a link with eosinophilic #esophagitis.
https://t.co/2tZF3HI1D3

[Wright Doyle Lab @WrightDoyle_lab]

Congratulations to Aliviya Schulze! First place for overall best poster in the Mayo Clinic Summer Undergraduate Research Fellowship poster session. #AlfredsArmy

[Wright Doyle Lab @WrightDoyle_lab]

Together these results suggest a possible link between detergent as an environmental exposure and EoE. Further research is needed to understand if oral detergent exposure can induce an allergic response. (10/N)

[Wright Doyle Lab @WrightDoyle_lab]

Detergents in toothpaste and other household products may cause #EosinophilicEsophagitis
https://t.co/wZ98L6RTmC
#EoE #eosinophil @MayoClinic @PhxChildrens

Read this 🧵 for a summary of our recent article just published online @AllergyEaaci. (1/N)

[Wright Doyle Lab @WrightDoyle_lab]

Alarmingly, we are not the first to observe detergent-induced esophageal inflammation. Epstein et al noted similar changes in rats and published their findings in the Journal of the ADA in 1939 when detergent was first widely introduced as a component of toothpaste.(10/N)