Xiangmeng(Shawn) Cai

Biotechnology, 3D Genome, Genome editing

[Xiangmeng(Shawn) Cai @XiangmengCai]

I want to give special thanks to Michael Montgomery who conceived the idea of Swap-seq and babysat me at the start of grad school. Mike is such a creative scientist, an outstanding mentor, and, above all, a fierce friend. Thank you, Mike (and the Variant-EFFECTS team)!

[Xiangmeng(Shawn) Cai @XiangmengCai]

Have you ever looked at a gene in IGV or a genome browser and wondered “What are all those (ATAC-seq/H3K27ac/CTCF ChIP-seq/…) peaks doing?” 🤔 I’m thrilled to share that we developed a new technology called Swap-seq to answer that exact question.
https://t.co/GMC1MJTNzB

[Xiangmeng(Shawn) Cai @XiangmengCai]

In summary, Swap-seq can discover regulatory elements across mechanistic classes, reveal sequence rules, and generate datasets for evaluating and improving S2F models. It's applicable to many genes and cell types—we are excited to help set it up in your favorite system!