Dr. Maura Marcucci and Dr. @YazDaaboul discuss results from POISE 3 trial for perioperative BP management in non-cardiac surgery. Interview link here: https://t.co/8Ak48WByS1 #cardiology#surgery
ADAPT-TAVR trial: in TAVR patients, edoxaban similar to DAPT in incidence of leaflet thrombosis on CT scans, no difference in rate of new cerebral thromboembolism. Download full slides from ADAPT-TAVR here: https://t.co/A2kKGSaPBG #cardiology#tavr
GIPS-IV trial: sodium thiosulfate after MI not associated with reduction in infarct size. Download slides from GIPS-IV here https://t.co/Mn6VC7xvbW #cardiology
Results from Rilonacept Phase 2 trial presented at AHA 2019 show rapid resolution of recurrent pericarditis episodes and improvement in quality of life scores.
Full poster here:
https://t.co/FN0EytanEp
Sponsored by an unrestricted educational grant from Kiniksa
TWILIGHT-ACS slides presented at #AHA19 demonstrate that, in patients with NSTE-ACS undergoing PCI, continuing treatment with ticagrelor alone lowers risk of bleeding without increasing the risk of an ischemic event over one year.
Full slide deck: https://t.co/MAFWTyimFX
DAPA-HF Substudy slides presented at #AHA19 demonstrate that Dapagliflozin could potentially be used to treat HFrEF in patients with and without diabetes.
Full slide deck: https://t.co/vo0sk6pJBZ
ORION-10: Inclisiran, a twice-yearly siRNA injectable reduced LDL-cholesterol levels by 58% in pts with ASCVD and elevated LDL compared with placebo.
Full slides are posted here: https://t.co/qE0MuMWnDC
Sponsored by an independent educational grant from The Medicines Company
EVAPORATE Trial slides presented at #AHA19 suggest Icosapent Ethyl in addition to statin therapy provides benefit on plaque characteristics.
Full slide deck: https://t.co/XpmyCxtn3h
Patients w/ stable CAD & moderate-severe ischemia experiencing angina had early & sustained improvements in angina and QoL w/ an invasive strategy compared to OMT in the ISCHEMIA Quality of Life data presented at
#AHA19
Review the full slides here:
https://t.co/x6pQzxNLWF
In pts with recent ischemic stroke or TIA & evidence of atherosclerotic disease, a target of <70 mg/dL LDL cholesterol had lower risk of subsequent CV events compared to pts w/ an LDL cholesterol target of 100+/-10 mg/dL #AHA19
View the full deck here: https://t.co/8UoF0b0c8h
Dr. Uma Sinha Presents: Differential Transthyretin Binding, Kinetic Stability and Additive Ex Vivo Stabilization by AG10 Compared to Tafamidis
View the full poster here: https://t.co/rV1vEqOYUI
Sponsored by an unrestricted educational grant from Eidos Therapeutics
ORION-9 slides presented at #AHA19 demonstrate a highly significant lowering of LDL-C relative to placebo with Inclisiran for patients with Heterozygous Familial Hypercholesterolemia.
Full deck here: https://t.co/X1RlMOFQuK
The late-breaking science continues! COMPLETE: staged complete revasc superior to culprit only revasc in reducing CV death/MI/revasc in patients with STEMI and multivessel CAD #ESCCongress
In an RCT of 31,492 patients with suspected acute coronary syndrome, a rule out pathway using a hs-TnI risk stratification threshold of 5ng/L reduced length of stay by 3.3hrs (57% ⬆️ in ED discharge) with no evidence of harm at one year #ESCCongress#HiSTORIC#troponin
More stunning results published in NEJM. ISAR REACT 5. Prasugrel vs ticagrelor for ACS:
Prasugrel reduces death/MI/stroke at 1 year. No difference in bleeding. Wow.
#ESCcongress2019