@tompowles1 Endoscopic surgery can't address N1 lymph node cases; these lesions rely entirely on EVP for control. Concerned about tumor recurrence & progression post-9 EVP cycles. Monitoring closely is crucial
@tompowles1 But in cases of T3b (visible extravesical mass), complete resection is unlikely. As for T4a, tumors invading the prostate may still be addressed with TURBT, whereas those extending into the seminal vesicles, uterus, or vagina exceed the scope of endoscopic surgery
@tompowles1 Similarly, endoscopic surgery can't control N1 lymph node cases; these lesions rely entirely on EVP for control. Concerned about tumor recurrence & progression post-9 EVP cycles. Monitoring closely is crucial
@tompowles1 When radiotherapy is omitted, TURBT becomes the sole local treatment modality. Achieving complete tumor resection via TURBT is the preferred approach whenever possible. For patients with T3a tumors (microscopic invasion of perivesical fat), TURBT may be a suitable option,
@tompowles1 Since complete tumor removal is trickier with ureteroscopic methods compared to TURBT, this study might also explore the efficacy and safety of ADC+ICI-based approaches for organ-preserving treatment in urothelial cancer. Can’t wait to see early results from these trials soon!
@tompowles1 Coincidentally, I’m starting a similar investigator-initiated study focusing on UTUC kidney-sparing treatment using 9 cycles of EV + Toripalimab alongside ureteroscopic laser ablation.
We’re thrilled to welcome Dr. Robert Jones to Chengdu! His insights on urothelial & prostate cancer management were truly inspiring. Honored to share our experiences on perioperative care for high-risk & bilateral UTUC. Great exchange of knowledge! 🙌 #UTUC#Urology
Honored to participate in the outstanding uro-oncology conference chaired by Dr. Dingwei Ye & Dr. Yao Zhu. Glad to meet many well-renowned experts and old friends. I am also honored to share our experiences on managing bilateral UTUCs. #Urology#UTUC#KidneySparing#UroOncology
Excited to share our pilot study results on nephron-sparing therapy for high-risk localized UTUC at #ESMO2024! Preserving kidneys in selected high-risk patients through a combo of local (endoscopic laser ablation, segmental ureterectomy) and tailored systemic therapy.
Kudos to Dr. Dingwei YE and Dr. Yao ZHU for adeptly organizing the 2024 Asia Pacific Prostate Cancer Perceptorship! It was a privilege to talk about de-escalation strategies for metastatic hormone-sensitive prostate cancer (mHSPC).
Just had an incredible day in Chengdu with Dr. Fred Saad! 🌟 His talk on bone-targeted therapy and prostate cancer research was truly inspiring.Honored to present our data to such a legend in the field. #ProstateCancerResearch#Inspiration#MedicalCommunity
Exciting news! Our data from the high-risk UTUC nephron-sparing trial has been accepted at ESMO 2024! Demonstrating the potential to preserve kidneys in carefully selected high-risk UTUC patients. #ESMO2024#UTUC#NephronSparing