For microbiome, we enable methylation binning using @nanopore seq + plasmid mapping + misassemblies detection. We found abundant 5mC motifs, suggesting previous underestimation and many new research opportunities. BTW. We're hiring, join us?! Full Ad: https://t.co/cjeiVZ0MfL 3/3
Bacterial 6mA & 4mC studies in the past 10 yrs mainly powered by @PacBio seq. NanoDisco now enables the use of @nanopore seq for de novo 6mA, 4mC & 5mC motif discovery (Software https://t.co/1aE5R2UUMw). The two platforms are still complementary as discussed in our new paper. 2/3