Katherine Jones

@UMNChemistry Ph.D. candidate in @DanHarki group. Forever screening small molecules and playing around with the random number generator (aka mass spec!).

[Katherine Jones @_ChemKat]

This synthesis might be incredibly frustrating, but at least I get a pretty looking column out of it! #RealTimeChem

[Katherine Jones @_ChemKat]

Very excited to have this paper from my time in grad school published! Started from an unrelated project idea that lead to weird results. Working on #APOBEC3A? Your catalytic inactivation mutation may lead to unstable protein! Check out the paper below to learn why E72A > E72Q.

[Dan Harki @DanHarki]

New publication from our lab and collaborators! Congrats to @_ChemKat, @Shehata92, @B1ocheMiker, and @RommieAmaro. #TeamAPOBEC, @UMN_MedChem @UMNChemistry @UMNCancer https://t.co/zvTHduxEy6

[Katherine Jones @_ChemKat]

@DanDempe Thanks Dan!!

[Katherine Jones @_ChemKat]

If you’re at #ACSFall2022 and you love drug discovery, come see me present my poster on our virtual and in vitro screening project for APOBEC3B inhibitors!

[Dan Harki @DanHarki]

Wednesday presentations by #HarkiLab members at #ACSChicago2022. Check out the work by ⁦@_ChemKat⁩ and Michael Grillo to develop ligands targeting APOBEC3B DNA cytosine deaminase. ⁦@AcsMedi⁩ @UMNChemistry⁩ ⁦@UMN_MedChem⁩.

[DRMP @DRMP2025]

PAPER OUT !! 🎉🥂🍾 @nature

https://t.co/v8SYc4vMfB

Viral restrictor APOBEC3A is a major cause of mutational signatures found in >50% of cancers + more, Tweetorial👇

With @J_Maciejowski

Via WGS/251 cancer clones (available!)

@broadinstitute
@MSKCancerCenter
@sangerinstitute

[Katherine Jones @_ChemKat]

Honored to have received this fellowship alongside these other amazing chemists!

[UMN Department of Chemistry @UMNChemistry]

Congrats to PhD students Margaret Clapham, Brianna Collins, Mckenna Hanson, Hannah Holst, and Katherine Jones for receiving highly competitive #UMN Doctoral Dissertation Fellowships! https://t.co/stxdtVF0uo #UMNproud @UMNCSE

[Katherine Jones @_ChemKat]

If you’re looking for a postdoc position in medicinal chemistry or chemical biology, come join our lab! #chempostdoc

[Dan Harki @DanHarki]

I am looking to fill at least 3 postdoctoral positions in the #HarkiLab @UMN_MedChem. Check out the team and projects at https://t.co/cNOi9VidNs.

[Katherine Jones @_ChemKat]

Exciting new research from @jtang162 that I was happy to be a part of is finally out in the world! Folks at #AACR22, go to his talk this afternoon!

[Dan Harki @DanHarki]

New lab #preprint! HLB-0532259: A chemical degrader of N-Myc that targets Aurora kinase A. Want to hear the development story in-person? @jtang162 from the #HarkiLab will present at #AACR22 today - 3:05 pm, New Orleans Theater B. @UMN_MedChem @UMNCancer
https://t.co/lCWoGQzl9I

[Katherine Jones @_ChemKat]

Our review (@DanHarki @HarrisLabUMN) on the current toolbox for APOBEC3 drug discovery is online now at @TrendsinPharma! So happy to see my first review paper finally out in the world! https://t.co/rsLqiWn0PS

[Dan Harki @DanHarki]

The 2022 version of the #HarkiLab! @UMN_MedChem @UMNChemistry @UMNCancer

[Katherine Jones @_ChemKat]

@breakliquid This reaction was methylating a quinolone with methyl iodide! The first step in hopefully, eventually, maybe resynthesizing a screening hit.

[Katherine Jones @_ChemKat]

This synthesis might be incredibly frustrating, but at least I get a pretty looking column out of it! #RealTimeChem

[Katherine Jones @_ChemKat]

@cathleencrudden Thank you!!

[Katherine Jones @_ChemKat]

@RacicotLeanne OMG YES!! Love it.

[Katherine Jones @_ChemKat]

@jruddchemist Nice! That's always the best because you can watch the separation as the column runs!

[Katherine Jones @_ChemKat]

@heydebigale I call this one a “tequila sunrise”!

[Katherine Jones @_ChemKat]

@firouzi_nima It’s actually just a simple methylation reaction with iodomethane! The purple is the iodine byproduct, my product is in the yellow stuff.

[Katherine Jones @_ChemKat]

@DanHarki No, it's the synthesis I've been working on (and failing repeatedly) for six months! The reaction I showed in group meeting this week worked, so I have to scale up to get more material to finish.

[Katherine Jones @_ChemKat]

A COVID Saturday night means board games feat Polyoply, the polymer version of Monopoly feat @UMNChemistry professors

[Katherine Jones @_ChemKat]

Also a reminder for any grad student being paid by a not pre-taxed fellowship like the NSF GRFP!

[Katherine Jones @_ChemKat]

@KTPhos Would you rather have a DART or this MasSpec Pen in lab?

[Eberlin Lab @EberlinLab]

Have you ever wondered what meat you are actually eating? 🤔 Check out our new paper using the MasSpec Pen as a rapid method and easy-to-use device for meat authentication, as shown in our fun video demo! https://t.co/sOMLdJ6zmC