Exciting breakthrough technology from the lab, now live in @CellCellPress ! Instead of cutting the genome where proteins bind (e.g., Cut&Tag), D&D-seq scars the DNA with a deaminase, allowing single cell genome mapping of TFs and chromatin remodellers!
Beautiful story from @XiaofengFangLab showing that the SAM-containing protein SAM8 acts as a sensor of water potential and regulates RNA export under stress.
Another fascinating link between polymerization domains, stress sensing, and RNA biology.
https://t.co/I1pbsOYhQh
RESEARCH PAPER: Glc7/PP1 triggers Paf1 complex dissociation from RNA polymerase II to enable transcription termination
By Sanchirmaa Namjilsuren and Karen Arndt
➡️ https://t.co/aqF6SOSRKy
@PittBioSci@PittTweet#transcription
One of the positive things about doing science in Israel these days is that every time your enzyme or antibody actually shows up, it feels like a miracle 😅
Breaking news: Indiana University plant microbiologist Roger Innes has been locked out of his laboratory by the school in response to a request by one of his federal funders. The move comes after Innes complained about the government’s prosecution of Chinese postdocs. https://t.co/2I7IpaYoKb
🆕 review with @jp_unfried out in @NatureSMB 🧐. Direct roles of lncRNAs in transcriptional activation. What do we understand about how lncRNAs lure Pol2 and set the stage for RNA production, and what do we still miss? https://t.co/iYJQ7Rbb9d