Mathias L. Nielsen

Postdoc in @IgorUlitsky lab @WeizmannScience 🇮🇱| lncRNA, transcription, and chromatin enthusiast 🧬| #LGBTinSTEM 🏳️‍🌈| he/him | 🇩🇰🇪🇺

[Dan Landau @landau_lab]

Exciting breakthrough technology from the lab, now live in @CellCellPress ! Instead of cutting the genome where proteins bind (e.g., Cut&Tag), D&D-seq scars the DNA with a deaminase, allowing single cell genome mapping of TFs and chromatin remodellers!

[Mathias L. Nielsen @_MathiasLN]

When even the airport security guard questions your decision to switch from plant biology to mammalian research😅

[Mathias L. Nielsen @_MathiasLN]

@XiaofengFangLab Good, thank you. Soon finishing my postdoc here.
Really exciting to follow your fascinating work on condensates, congratulations!

[Mathias L. Nielsen @_MathiasLN]

Beautiful story from @XiaofengFangLab showing that the SAM-containing protein SAM8 acts as a sensor of water potential and regulates RNA export under stress.

Another fascinating link between polymerization domains, stress sensing, and RNA biology.

https://t.co/I1pbsOYhQh

[Mathias L. Nielsen @_MathiasLN]

Almost four years since I left my PhD lab, and still not a day goes by without me hearing something my supervisor used to say in my head.

[Nature Biotechnology @NatureBiotech]

Photosynthesis in mammalian corneal cells boosts energy production and reduces inflammation #NBThighlight https://t.co/kvtTMZuEG4

[Mathias L. Nielsen @_MathiasLN]

Most important information for the next few hours 👇👇 🇩🇰

[Nature Biotechnology @NatureBiotech]

Widespread DNA off-targeting confounds RNA chromatin occupancy studies https://t.co/1ajHMk8RQG

[Genes & Development @GenesDev]

RESEARCH PAPER: Glc7/PP1 triggers Paf1 complex dissociation from RNA polymerase II to enable transcription termination
By Sanchirmaa Namjilsuren and Karen Arndt
➡️ https://t.co/aqF6SOSRKy

@PittBioSci @PittTweet
#transcription

[Mathias L. Nielsen @_MathiasLN]

One of the positive things about doing science in Israel these days is that every time your enzyme or antibody actually shows up, it feels like a miracle 😅

[Mathias L. Nielsen @_MathiasLN]

The best thing about FACS is the time it gives you to read papers while the machine decides whether a cell is actually red.

[Mathias L. Nielsen @_MathiasLN]

Crazy story

[News from Science @NewsfromScience]

Breaking news: Indiana University plant microbiologist Roger Innes has been locked out of his laboratory by the school in response to a request by one of his federal funders. The move comes after Innes complained about the government’s prosecution of Chinese postdocs. https://t.co/2I7IpaYoKb

[NatureStructMolBiol @NatureSMB]

New online! Direct roles of long non-coding RNAs in transcription activation https://t.co/NW9GyZXvbk

[Igor Ulitsky @IgorUlitsky]

🆕 review with @jp_unfried out in @NatureSMB 🧐. Direct roles of lncRNAs in transcriptional activation. What do we understand about how lncRNAs lure Pol2 and set the stage for RNA production, and what do we still miss? https://t.co/iYJQ7Rbb9d

[Genes & Development @GenesDev]

🆕 ADVANCE ONLINE 🆕

RESEARCH PAPER: The conserved N-terminal SANT1-binding domain (SBD) of EZH2 regulates PRC2 activity
By Patriotis et al., and the late David Allis
➡️ https://t.co/mkeojloefS

@ael2b @RockefellerUniv @epicypher
#epigenetic #histone #polycomb #lymphoma

[Mathias L. Nielsen @_MathiasLN]

@drdrdaria Opbygning til en deal (forhåbentlig). Klassisk Trump: først panik, så som manden der løser alt.

[Mathias L. Nielsen @_MathiasLN]

When your protocol says: “immediately perform” how important is it actually..🧐😅

Maybe I should just do the whole thing in the shelter.

[Mathias L. Nielsen @_MathiasLN]

“Negative observations are still valuable science”.

True in the lab and apparently also when you fly around the moon.

#ArtemisII

[Lea Haarup Gregersen @GregersenLab]

❗️5 days left to apply for a PhD position in our group👇

[Mathias L. Nielsen @_MathiasLN]

Denmark issuing a “be aware of potential attacks” warning after a month of attacks is peak Danish