Charlotte K

Scientist

[Charlotte K @__CharlotteK]

If you are interested in malaria control strategies and want to know more about ivermectin, come talk to me or check my poster at the 31st PAGE conference in A Coruña, Spain! 🦟💊

https://t.co/igBzNu7Up7
@inselgruppe @unibern @UniBasel @ISGLOBALorg @KEMRI_Kenya @NDMOxford

[Charlotte K @__CharlotteK]

Interested in malaria control strategies? Our new study published in @MalariaJournal finds that ivermectin's metabolites contribute to the parent drug mosquito-killing activity 🦟🩸💊

https://t.co/739kJcCP5t

@inselgruppe @unibern @UniBasel @ISGLOBALorg @UNITAID @SwissTPH

[Charlotte K @__CharlotteK]

Always a pleasure to meet again pharmacometricians from all over the world!!

[PAGE @page_meeting]

With nearly 900 registered participants and 422 submitted abstracts, the record-breaking 3️⃣1️⃣st PAGE meeting has kicked off this morning in A Corūna 🇪🇸!

[PAGE @page_meeting]

With nearly 900 registered participants and 422 submitted abstracts, the record-breaking 3️⃣1️⃣st PAGE meeting has kicked off this morning in A Corūna 🇪🇸!

[Dr. Carlos Chaccour 🦟🔚💊 @Carlos_Chaccour]

Pharmacokinetics of ivermectin metabolites and their activity against Anopheles stephensi mosquitoes

https://t.co/GE81O9hImp

Great work by @__CharlotteK @felixhammann @UDuthaler et al.

[Charlotte K @__CharlotteK]

@felixhammann Right :D

[Felix Hammann @felixhammann]

"Awaiting editorial decision"

[Marta Maia @MartaFerreiraM2]

The Kenya BOHEMIA team following a successful symposium on endectocides for malaria vector control #KASH_2023 #KEMRI_Wellcome #BOHEMIAProject

[Felix Hammann @felixhammann]

All in all good news for malaria vector control and certainly helpful for repurposing ivermectin for this indication.

@__CharlotteK @Carlos_Chaccour @UDuthaler

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[Felix Hammann @felixhammann]

Two active metabolites (M1, M4) had longer half-lives than IVM in human volunteers. This may explain why blood retains mosquitocidal activity even after IVM is no longer detectable (‘post-ivermectin effect’).

3/

[Felix Hammann @felixhammann]

Three metabolites produced by CYP3A4/5 (M1, M2, M4) were active against An. stephensi at concentrations seen in one of our prior trials in human volunteers.

2/

[Charlotte K @__CharlotteK]

Check out our latest research findings in #malariacontrol

[Felix Hammann @felixhammann]

New study finds that #Ivermectin metabolites contribute to mosquitocidal action & may be responsible for the ‘post-ivermectin effect’ in #malaria control.

👉Preprint: https://t.co/BkFyXQ2iLX

@inselgruppe @unibern @UniBasel @ISGLOBALorg @UNITAID @SwissTPH

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[Charlotte K @__CharlotteK]

@Vinz_Sorrentino @Kei__Sakamoto @HealthyLongeviT Congratulations Vincenzo!!!

[Charlotte K @__CharlotteK]

Check out our interview by @unibern with @DBremae on our modeling and simulation projects at @inselgruppe

[Universität Bern @unibern]

#Women in data science are an exception - or are they? Charlotte Kern & Verena Schöning used simulation & coding to directly contribute to improved patient care during #COVID: https://t.co/CsnE4lPFVj
#unibern #womeninscience #artificialintelligence #CAIM @inselgruppe

[Charlotte K @__CharlotteK]

@MKugemann @inselgruppe @unibern thank you so much for this great honor!

[Monika Kugemann @MKugemann]

Charlotte Kern, clinical pharmacology @inselgruppe winning the Young Researcher Award at the #Research Symposium for #ArtificialIntelligence in #Medicine for her #pharmacometric #modeling of antiviral therapy against #COVID19 variants. #diversity #CAIM @unibern

[Felix Hammann @felixhammann]

@__CharlotteK showing which ivermectin metabolites kill mosquitoes as part of #BOHEMIAproject over at #TropMed2022

@UNITAID @inselgruppe @SwissTPH @UniBasel @ISGLOBALorg

[Charlotte K @__CharlotteK]

@ISBSIB @fredericschutz @unil @USI_en @unibern @EPFL_en @ZHAW @ETH_en @UZH_en @VallergaArianna @Giulia_Muzio @alisaadat77 @percyfanbw1 Thanks for the great workshops!!