tux pacific

she/her; former founder/CEO @entropydotxyz (RIP 2021 - 2025)

[tux pacific @__tux]

I am winding-up Entropy.

After four years, several pivots, and two rounds of layoffs, I’ve decided to wind-up Entropy and return capital to our investors.

For the latter half of 2025, the Entropy team was hard at work on a crypto automations platform (basically n8n/zapier/etc for crypto) with the addition of automated signing using threshold cryptography, secure computation via TEEs, and deep AI integrations.

After an initial feedback request revealed that the business model wasn’t venture scale, I was left with the choice to find a creative way forward or pivot once more. After four hard years working in crypto, I decided that the best I could do has already been done: it was time to close up shop.

I have a lot to say on “giving up”, maybe for a different time. I’ve never once given up in my career. The only thing I’ve ever quit was college, so this makes the second thing. It’s challenging, but I find peace in the fact that a career is a practice: the goal is not the destination, but the journey of innovation. Every step is a new result towards something even bigger than before.

The remaining team is exceptionally skilled: a brilliant software engineer (soon, a likely founder), an insanely talented and hungry product marketer, and the best and most talented product designer i’ve ever had the pleasure of working with. If any of these profiles fit your needs, please reach out and I’ll try and provide a double opt-in. These folks have been the best team a founder could ask for.

As for me, I’ll be taking a much needed break to do research on my next venture, spend time relaxing, and making art.

My time in crypto might be coming to an end, as I feel myself drawn specifically into pharmaceuticals: I want to innovate on hormone delivery, specifically for women who experience menopause and trans women for HRT. I will be spending my time validating my research on new Estradiol drug formulations, as well as biophysics and organic chemistry. If you have experience in the pharma or medicine space, please reach out!

Special thanks to @a16zcrypto and @guywuolletjr for being exceptionally helpful throughout this process. Their guidance has been invaluable.

Thanks to everyone who has been involved: without y’all, none of this would have been possible.

Thank you,
Voltairine Novatore Pacific (aka Tux)

[tux pacific @__tux]

@baynoni 💯💯💯

[tux pacific @__tux]

@baynoni its the only one that really just seems like a genuine humiliation ritual until it’s good enough

[Enara @enaraxr]

https://t.co/PVSGZTPT1P

[tux pacific @__tux]

@baynoni high key, the trick is to feel it in your body, let it out, and then be like “okay, we felt that, let’s move onto something else now” — that, gratitude, and maybe exercise.

idk that’s what helps me cope

[tux pacific @__tux]

@LefterisJP who tf wants to be there on a 40C day??

[tux pacific @__tux]

i shoot righty, i think. which is really odd cause i’m right handed, but it somehow feels slightly more comfy than lefty? does anyone have any insight here?

[tux pacific @__tux]

she’s a hockey player, marcus!!

[tux pacific @__tux]

@alexpotato no that was grindr lol

[tux pacific @__tux]

over a decade ago, the twitter API let you define a geo box to get tweets from within it.

i had a whole tool that was collecting a ton of data from people at sensitive military locations.

frequent tweeters could be tracked by making larger boxes until you found their homes or other frequent spots.

i don’t remember how long this went unpatched for, but it was fun while it lasted.

[Tobias Schneider @tobiaschneider]

When we first discovered the Strava open-source vulnerability some years ago, we would upload spoofed 50-centimeter GPS vectors on the doorsteps of loads of sensitive buildings, and it would just give us clear names of everyone who walked in and out with one of those watches

[tux pacific @__tux]

@Bonecondor @stwrawrbewry you don’t get them from IM injections either

[tux pacific @__tux]

@baynoni shoulda asked to get a serial number in my skull just in case

[Kyle Cushman @Kyle_Cush]

Victoire announce Marie-Philip Poulin played through a torn ACL and meniscus.

Poulin was injured at the Olympics and reinjured in March in the PWHL. She played through the injury in the playoffs, winning the Walter Cup and Playoff MVP.

[tux pacific @__tux]

@stepan__nazarov at least that’s what i remember doing, it was over a decade ago that i did this.

[tux pacific @__tux]

@stepan__nazarov basically, you do a geographic search by creating multiple boxes within a larger area and then you keep getting smaller and smaller til you identify it in a specific location.

[Kirsti Miller @KirstiMiller30]

In sports without weight categories, height and weight do not meet the threshold to be considered characteristics involved with “intolerable unfairness.”

Advantages due to being taller or heavier in these sports (e.g., basketball, volleyball, rugby) are not currently considered “unfair”.

The average NBA player, for example, is nearly 10 inches taller than the average man and 40 pounds heavier.

Male and female muscle is the same strength when comparing equivalent cross section/size.

Much of the increased strength of cis-men compared to cis-women can be explained by height differences.

When adjusting for height and fat free mass, this relative difference disappears. Lean body mass increases with height for both men and women.

Suppressed testosterone in trans women results in reduced muscle mass over time and inhibits the ability to build as much muscle as those who have their normal or high concentrations of testosterone.

The limiting factor in endurance sport is not the size of an athletes lungs. The limiting factor is the oxygen carrying capacity of blood (red blood cell count which is affected by hormones.

Without a doubt the single most important physiological factor for endurance athletes is hemoglobin.

In sports it’s often measured as hematocrit levels. Hematocrit is the percentage of blood that's red blood cells.

That's the reason that endurance athletes go to altitude to train, or [those who cheat] use blood doping or EPO. There are a lot of things that go into making an endurance athlete, but the single most important factor would be hemoglobin levels.

Testosterone suppression reduces the oxygen-carrying hemoglobin in blood to cisgender female levels after around three months of GAHT.

A trans woman's body with their reduced levels of the oxygen-carrying hemoglobin in their blood will be significantly underpowered.

Trans women have less delivery of oxygen to the working muscles produces a higher rate of metabolites and consequently results in muscle fatigue.

While estrogen supplementation greatly increases the total body fat percentage in trans women.

This results in what we call reduced fat-free mass. Fat provides resistance for movement, as opposed to a muscle, which provides torque for movement. Consequently, the more fat-free mass someone has, the better athlete they are likely to be — independent of skill level.

A relatively unknown study from 2021 took strength data from eight trans women and eight matched cisgender males and females. It found that the measured strength of trans women was not as low as cis women, but nowhere near as high as cis men.

But when the strength of cis men and women was divided by their fat-free mass, they were equal. Conversely, when trans women's strength was divided by their fat-free mass, they were around 19% weaker, kilogram for kilogram, than cis men and women.

https://t.co/9gKXUwiS6d 

Alvares et al (2022) noted trans women had a lower VO2 peak/lean mass index,& lower mean strength/lean mass index than both cis women & cis men.

Trans women once again produced less force per gram of muscle than both cis women & cis men.

https://t.co/TFMER2CLOM

Based on this data, a cisgender male and a trans woman cannot be equated. 

Existing research suggests that transgender women do not equate to cisgender men in either physiological or performance terms.

Testosterone suppression coupled with estrogen supplementation (on a case by case basis) is the best way to make decisions for the eligibility trans women competing in the female category of sport. 

It's ultimately a question of how long that treatment should be for each athlete and each sport.

Cheung & colleagues suggest, REASONABLE  accommodations for the inclusion of TRANS WOMEN are sport specific & COULD be based on the range of competitive ADVANTAGES & ABILITIES that are ALREADY  accepted in the CIS FEMALE population.

https://t.co/Xe0hWKXYsk

https://t.co/Nk5PKIeWCF

[tux pacific @__tux]

wild to assume that i'm on a first name basis with these people

[tux pacific @__tux]

“how’s crypto going in this economy?”

crypto:

[tux pacific @__tux]

@EllaYurman i’m ready for my comedy writing career to begin just holla at me

[tux pacific @__tux]

SNL skit where it’s a MAGA dressed as a SS officer at a detention camp for anti american activity trying to find who is transgender by going down a line up of prisoners and playing jungle/DnB drops to find the girl who starts jumping like hunter

[໊ @eusexua]

hunter schafer and fka twigs queening out in seoul korea

[tux pacific @__tux]

@ooi43z T can help, but HGH support during puberty helps more