Strongly absorbing dyes, such as a common food color tartrazine, temporarily render live animal tissues transparent, enabling deep optical imaging of internal structures and activities.https://t.co/ob9zW3VSCQ #NBThighlight
i am so excited about our open source inexpensive, sub-cellular capture, do-it-yourself Open-ST that transforms tissues into virtual tissue blocks in 3D - IDing pathways & gene programs driving phenotypes. a huge congratz to the team! https://t.co/UvyBdFGZRX
uLIPSTIC is a new method from the @victora_lab for directly observing physical interactions between cells: https://t.co/EdVFH35Omb
Victora: “With uLIPSTIC we can ask how cells work together, how they communicate, and what messages they transfer. That’s where biology resides.”
https://t.co/so6bP1Qa64
Can we predict response to treatment with circulating biomarkers?
We tried to answer this question through a fine literature selection about advanced melanoma patients treated with immunotherapy
#Melanoma#Circulating#Biomarkers#Immunotherapy#response
A spatial transcriptomics method that…
🧪is easy to use
🔬has high resolution
🪙is cost-efficient
🌍scales to 3D
Just in time for Xmas:
Open-ST, a end-to-end, open-source method that checks all boxes, from the @N_Rajewsky lab
📄Preprint: https://t.co/DJmkJSlCKH
🧵⬇️
here it is- read about 3D virtual tissue blocks, metastasis-lymph node boundaries and unlocking molecular mechanisms in 3D. biggest congratz to the entire team. Open-ST: High-resolution spatial transcriptomics in 3D | bioRxiv https://t.co/7IFSPmqlZS