Sandeep Chivukula

product exec. agentic AI + longevity
Book me here:

[Sandeep Chivukula @_sandeep]

@stophe 🚀🚀🚀

[Sandeep Chivukula @_sandeep]

I work with product leaders and founders on agentic AI — how to cut through the hype and actually use it to build better products faster.
Book me here 👉 https://t.co/uiTauFVPqG

[Sandeep Chivukula @_sandeep]

For most of my career, the best kept secret about building great products was simple.

✨ Talk to your users. ✨

[Sandeep Chivukula @_sandeep]

Now I'm doing something I haven't done before. Opening my calendar for 1:1 calls on Intro.

[Sandeep Chivukula @_sandeep]

Is there an agent to keep up with all the agents?

[Todd Saunders @toddsaunders]

The token cost to build a production feature is now lower than the meeting cost to discuss building that feature.

Let me rephrase.

It is literally cheaper to build the thing and see if it works than to have a 30 minute planning meeting about whether you should build it.

It’s wild when you think about it.

This completely inverts how you should run a software organization. The planning layer becomes the bottleneck because the building layer is essentially free. The cost of code has dropped to essentially 0.

The rational response is to eliminate planning for anything that can be tested empirically. Don’t debate whether a feature will work.

Just build it in 2 hours, measure it with a group of customers, and then decide to kill or keep it.

I saw a startup operating this way and their build velocity is up 20x. Decision quality is up because every decision is informed by a real prototype, not a slide deck and an expensive meeting.

We went from “move fast and break things” to “move fast and build everything.”

The planning industrial complex is dead.

Thank god.

[William A. Wallace, Ph.D. @WilliamWallace]

One week of short sleep in otherwise healthy adults. Not "sleep deprived" by strict definition. Just 4-5 hours a night. Testosterone dropped 15%. Insulin sensitivity dropped 20%. Muscle protein synthesis dropped 19%. Hunger hormones rose 28%. Cortisol rose 51%. These aren't the only systems affected. They're just some of the ones that have been measured in controlled settings. No supplement, no diet hack, no training program (crazy claim, I know, but you can't outrain poor sleep...) outperforms sleep at keeping systems "online".

References:
Leproult & Van Cauter, JAMA, 2011. Buxton et al., Diabetes, 2010. Zuraikat et al., Diabetes Care, 2024. Spiegel et al., Lancet, 1999. Saner et al., J Physiol, 2020. Spiegel et al., Ann Intern Med, 2004.

[Qiusheng Wu @giswqs]

Introducing anymap-ts: a new Python package that makes geospatial visualization easy!

Built on MapLibre + TypeScript, anymap-ts brings the same rich mapping experience to both the web and Jupyter Notebook. It supports many popular geospatial formats, including GeoJSON, GeoParquet, FlatGeobuf, PMTiles, COG, Zarr, COPC LiDAR, and Gaussian Splat.

It also includes powerful built-in UI components such as a minimap, bookmarks, print tool, view state manager, STAC search, street view, and geometry editor.

Try it out:
Web demo: https://t.co/sktYpsK6i9
Jupyter demo: https://t.co/38gJG8e60m

GitHub: https://t.co/rJ0pLMrrbU
Documentation: https://t.co/u6rOGlrIe3
Video tutorial: https://t.co/1Wsv85kXdr

#mapping #maplibre #typescript #jupyter #python

[Sandeep Chivukula @_sandeep]

In this morning's @claudeai Cowork talk - @bcherny's single biggest use case is not having to manually route info from spreadsheets and to Slack for project management. Siloed context is a problem.

More on Personal OS and unifief context here:
https://t.co/exvXz192Xe

[Sandeep Chivukula @_sandeep]

Wrote more in detail here: https://t.co/exvXz192Xe

[Sandeep Chivukula @_sandeep]

Why is Clawdbot/Moltbot/Openclaw going viral?
Context is trapped in app silos. We waste high-leverage time manually routing data between Slack, email, and calendars. @openclaw signals a shift to a #PersonalOS that let's the user own the context layer.

[Sandeep Chivukula @_sandeep]

Also, avoid the productivity vanity trap. Do not settle for AI slop output. No one cares how many reports you created. or how fast your agent clicked buttons. A competitor with ten-year context with real outcomes will outrun you. Build a context moat that compounds.

[ゆうもや @takex5g]

Claude Coude、毎回キーボード触るの面倒すぎて、物理承認印鑑をつくりました。

これを使えばジャパニーズトラディショナルな気持ちでバイブコーディングできます。普通にちょっと便利

[Shane Gu @shaneguML]

If you are an AI safety researcher, book a flight ticket to Tokyo now and watch the "AI dog in chain" art exhibition. Our pre-training data is evolution and mostly physical intelligence. It's the best way to witness and ponder on the meaning of AI safety.

[Ya'el Courtney, PhD @ScienceYael]

I feel like I'm late to the Claude Code train but WOW

<60 seconds to write a script to take Cell Ranger Multi outputs across 3 different scRNAseq projects (23 samples) w/ GEX, VDJ, BCR info - merge to RDS, QC, filter, normalize, run PCA, integrate, UMAP, cluster

and 0 errors!

[Daniel J Drucker @DanielJDrucker]

Introducing the inflammatome, a comprehensive set of 2,000 genes consistently upregulated in various inflammatory diseases vs. healthy controls. https://t.co/Ygo1yEMDcQ

[Sandeep Chivukula @_sandeep]

2/ The Problem: High-leverage talent is stuck doing low-leverage routing. You act as the bridge between Slack, email, and Calendar. You are an information janitor. 🧹