Tumor localized CTLA4 blockade using a cleavable, conditionally activatable DVD IgG provides primary antigen-specific anti tumor efficacy in localized and systemic preclinical tumor models! Thanks as always to
@MarcelArias@lawfong for the mentorship!
https://t.co/3XW7WuCSUk
My lab’s 5-year NIH R01 grant, awarded to study gene therapy for hearing loss, was abruptly terminated. I want to share how this action has been incredibly harmful and disruptive, not just to my lab, but to the scientific process itself. 1/15
New #JITC article: Impact of tumor localization on antitumor immunity with conditionally activated CTLA-4 blockade https://t.co/g8SXyVr5p9 @MarcelArias@UCSF
In this great collaboration with Abbvie we found time-sensitive synergistic effects between immune checkpoint blockade therapy and JAK1 inhibition to increase T cell mediated anti-tumor immunity in mice! Thanks to @lawfong@MarcelArias for the opportunity! https://t.co/ODw1bZGCfv
Aram Lyu, Peiqi Ou, Helen Rizos, and Annette Paschen discuss "Cancer Immune Evasion" in a symposium at the AACR IO Conference on Discovery and Innovation in Cancer Immunology. #AACRIO25@HelenRizos@AramLyu
In this fantastic collaboration with Abbvie we were able to find time-sensitive synergistic effects between immune checkpoint blockade and JAK1 inhibition in boosting T cell fitness against tumors in mice. Online today! https://t.co/T0EbhEuAtw @lawfong
A big thank you to @fredhutch for the Science spotlight on some of our work investigating the effects of e-cigarette components in preclinical tumor models. As always thanks to @lawfong and @MarcelArias for the opportunity to work on this project! https://t.co/OXRWGVwPUy
https://t.co/GLREU3Ub45 thank you @fredhutch for the Science spotlight on our work on the effects of e-cigarette components in preclinical tumor models @lawfong@ProfGlantz
Natasha Ram was torn between wanting to be a physician and a researcher. So she decided to be both.
Now, Ram is among the elite students in @USFHealthMed's MD/PhD program, a rigorous 8-year course of study likened to the special ops of medical school. https://t.co/NnbhPfMnEG
#MCOM Dean Dr. Charles Lockwood and 4 of our MD-PhD students took center stage at the fall meeting of the USF Health Leadership & Innovation Forum of Tampa (LIFT). This is the perfect preface to a weekend celebrating 50 years of academic and clinical excellence at #MCOM.
@JamesEKHildreth Had to throw in a little poster resulting from a collab with that I presented this weekend, big thanks to @MarcelArias@lawfong, Willie Tsai, and Art Weiss for their mentorship throughout this project!
Day 1 of #SEMSS2024 at Vanderbilt! I’ll try to put some interesting findings the next two days in this thread for any undergraduates interested in physician-scientist training or any current MD/PhD or MSTP trainees:
Beautiful keynote speech by @JamesEKHildreth not just on his research hypothesizing HIV as a Trojan exosome and the expanded tropsim of pseudo types HIV, but also on his journey to become one of the most prolific researchers in the world. Truly inspiring!