Alex Man-Hei Yip

Postdoctoral Fellow at City University of Hong Kong👨‍🔬🧪🧫 Prof. Kenneth Kam-Wing Lo’s Lab @bhkenlo

[Alex Man-Hei Yip @aayyip]

Phosphorogenic Iridium(III) bis-Tetrazine Complexes for Bioorthogonal Peptide Stapling, Bioimaging, Photocytotoxic Applications, and the Construction of Nanosized Hydrogels @InorgChem4Life
#IC4LPoster #Bioinorganic

[Alex Man-Hei Yip @aayyip]

@Abinash_chem iridium(III) complex and the complex accumulated in the tumor cells. Normal cells release less extracellular MMP, therefore, a lower amount of the complex would be accumulated in the normal cells.

[Alex Man-Hei Yip @aayyip]

2023 #RSCPoster 𝐓𝐰𝐢𝐭𝐭𝐞𝐫 𝐂𝐨𝐧𝐟𝐞𝐫𝐞𝐧𝐜𝐞 #RSCChemBio #RSCInorg #RSCMat
Matrix Metalloproteinase (MMP)-responsive Iridium(III)-based Hydrogels for Tumor Cell-specific Imaging, Anti-metastasis, and Lysosome-targeted Photodynamic Therapy

[Alex Man-Hei Yip @aayyip]

@Abinash_chem The tumor cell-specificity was based on the release of MMP-2/9 by the tumor cells. Many types of tumor cells (for example, MCF-7 and MDA-MB-231) release more MMP-2/9, which can cleave the MMP-sensitive peptide implemented in the hydrogels, leading to the release of the cytotoxic

[Alex Man-Hei Yip @aayyip]

#RSCChemBio #RSCInorg #RSCMat

[Alex Man-Hei Yip @aayyip]

#RSCPoster

[Alex Man-Hei Yip @aayyip]

@EdGardner_ iridium(III) complex and the complex accumulated in the tumor cells. Normal cells release less extracellular MMP, therefore, a lower amount of the complex would be accumulated in the normal cells.

[Alex Man-Hei Yip @aayyip]

@EdGardner_ The tumor cell-specificity was based on the release of MMP-2/9 by the tumor cells. Many types of tumor cells (for example, MCF-7 and MDA-MB-231) release more MMP-2/9, which can cleave the MMP-sensitive peptide implemented in the hydrogels, leading to the release of the cytotoxic

[Eunice @EuniELF]

2023 #RSCPoster Twitter Conference #RSCChemBio #RSCInorg
Iridium(III) bis-Nitrone Complexes as Innovative Phosphorogenic Reagents for Bioimaging and Phototherapeutics

[Alex Man-Hei Yip @aayyip]

2023 #RSCPoster 𝐓𝐰𝐢𝐭𝐭𝐞𝐫 𝐂𝐨𝐧𝐟𝐞𝐫𝐞𝐧𝐜𝐞 #RSCChemBio #RSCInorg #RSCMat
Matrix Metalloproteinase (MMP)-responsive Iridium(III)-based Hydrogels for Tumor Cell-specific Imaging, Anti-metastasis, and Lysosome-targeted Photodynamic Therapy

[Alex Man-Hei Yip @aayyip]

@rsc_medchem We will try to make an injectable MMP-hydrogel containing the iridium(III) complex and study its effect on an MCF-7 xenograft mouse model later.

[Alex Man-Hei Yip @aayyip]

@rsc_medchem @rsc_medchem Thanks for coming and have a look at my poster! We are now working on the effect of the MMP-hydrogels on cancer cells grown in a 3D extracellular matrix environment.

[Alex Man-Hei Yip @aayyip]

@SjoerdSlagman Thanks for your appreciation😂🙈

[Angewandte Chemie @angew_chem]

Phosphorogenic Iridium(III) bis-Tetrazine Complexes for Bioorthogonal Peptide Stapling, Bioimaging, Photocytotoxic Applications, and the Construction of Nanosized Hydrogels (Lo) @CityUHongKong @CityUChem @bhkenlo https://t.co/c90bDi0i7A

[Alex Man-Hei Yip @aayyip]

@arlyh322 @3422049bc2f743b @SolomonYue

[Alex Man-Hei Yip @aayyip]

@SolomonYue

[Alex Man-Hei Yip @aayyip]

@RichScotford @SolomonYue Plz help...

[ChemEurJ: Chemistry - A European Journal @ChemEurJ]

#Photophysics, intracellular sensing, and photocytotoxic activity of #luminescent #rhenium(I)-polypyridine complexes by Kenneth Lo @bhkenlo, Cong Yu, and co-workers https://t.co/AEBaOsN7td

[ISPPCC 2019 @ISPPCC]

Through a series of e-postcards, we introduce scenes of different locations in Hong Kong. Photo: Dr Ben Chu.

ISPPCC 2019: https://t.co/4ZR0pUwXd7

[ISPPCC 2019 @ISPPCC]

Through a series of e-postcards, we introduce scenes of different locations in Hong Kong. Photo: Mr Robert Sia.

ISPPCC 2019: https://t.co/4ZR0pUOy4F