CONGRESS | #EULAR2025 | PLENARY SESSION
Antonis Fanouriakis, National and Kapodistrian University of Athens, gave a talk about recent advances in #SLE including pathogenesis, treatment strategy and major clinical trials in 2024-2025.
· Genetic burden of SLE may lead to transition from normal to preclinical autoimmunity and an IFN signature predicts progression from ANA positivity to SLE.
· Summary of 2025 ACR guidelines for SLE has been published.
· HCQ was associated with a reduced risk for any CV outcome but there was no protective role in the preeclampsia.
· HCQ continuation during GC withdrawal may help prevent flares.
· Early use of MMF prevents flares.
Achievement of remission and low disease activity is still low with belimumab and anifrolumab in clinical trials.
· Many trials are ongoing to investigate new agents for treating SLE, including CAR T-cell therapy.
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#RheumTwitter #rheumatology #MedNews #MedEd #MedicalCongress
Excited to share our freshly published work on the transcriptome and molecular clustering of AAVs! Congrats to the team! #boumpasteam
https://t.co/BQAyGZYlzF
Beautiful model for predicting cell-type specific 3D chromatin architecture and critical regulatory elements! Congrats @artsinyc and team! Can't wait to try it on our cells!
In science life, many things are celebrated: papers, grants, etc. This is all fine and good, but the pure joy that the new website of our lab has brought me is (almost) unrivalled! Please take a look:
https://t.co/Hmq8OJYwyX
And to those interested in our work, do get in touch.
We are excited to invite you in the 5th Lupus School organized by our lab!! You could also attend it online! #boumbasteam#sle#research#autoimmunedisease
https://t.co/ZP9TQUDlqM
Congrats to the team!
#boumpasteam#Lupus
Antiviral Innate Immune Responses in Autoimmunity: Receptors, Pathways, and Therapeutic Targeting https://t.co/ISN5xjTNV8 #mdpibiomedicines μέσω @Biomed_MDPI
Happy to participate in this great work.
ATR-mediated DNA damage responses underlie aberrant B cell activity in systemic lupus erythematosus. #SLE#DNAdamage#Bcells https://t.co/KOFoietb5U
BREAKING NEWS:
The 2022 #NobelPrize in Physiology or Medicine has been awarded to Svante Pääbo “for his discoveries concerning the genomes of extinct hominins and human evolution.”