Yanshu Shi

Hi, this is Yanshu Shi, and I am a postdoc working with Prof. Dan Anderson and Prof. Bob Langer for development of novel lipid nanoparticles for gene delivery.

[David R. Liu @davidrliu]

In a medical milestone, a customized base editor was developed, characterized in human and mouse cells, tested in mice, studied for safety in non-human primates, cleared by @US_FDA for clinical trial use, manufactured as a complex with an LNP, and dosed into a baby with a severe, rapidly progressing genetic disease... all in an astounding 7 months. Best of all, the infant patient shows apparent benefit. Congratulations to @kiranmusunuru, Rebecca Ahrens-Nicklas, and other team members for this heroic and inspiring effort, which has implications for the hundreds of millions of patients that suffer from thousands of genetic diseases.

https://t.co/wsgvvRYPVM

[Yanshu Shi @advancedlnp]

@AllenYJiang @UclaCBE Allen, that is great! Big congrts and all the best to your future!

[Yanshu Shi @advancedlnp]

@whl0903 @Nature @wangqenliang92 @KingRaychard @KaiWTang @UTBiomedical @UTAustin @NSF @NIGMS Thank you very much, Dr. Wang！It is my great honor to join this cool work!

[Huiliang(Evan) Wang @whl0903]

Excited to share our work in @nature on H-bonded organic frameworks as ultrasound-programmable drug delivery system! Congratulations to @wangqenliang92 @advancedlnp @KingRaychard @KaiWTang and all our collaborators! @UTBiomedical @UTAustin @NSF @NIGMS https://t.co/SkoXr2Lwrp