We wanna talk to people building the future.
Deep tech founders, engineers, researchers, robotics teams and student builders, we at @m33hq want to hear from you. Geek out.
We’ll read it all. Fill this form, and we'll hit you up soon: https://t.co/XaynjE7zJE
deeptech is just a sexy thing to do. everybody wanna do it, the builders, the founders, and (cant forget them) the investors. most of it is just hype; a lot of the ventures or projects are bound to fail because there is no substance to support the ambition, a lot of them, instead of having a novel technology/system, are a different perspective on the existing tech (low defensibility).
𝐒𝐨𝐮𝐧𝐝 𝐰𝐚𝐯𝐞𝐬 𝐜𝐚𝐧 𝐭𝐞𝐦𝐩𝐨𝐫𝐚𝐫𝐢𝐥𝐲 𝐨𝐩𝐞𝐧 𝐭𝐡𝐞 𝐛𝐥𝐨𝐨𝐝-𝐛𝐫𝐚𝐢𝐧 𝐛𝐚𝐫𝐫𝐢𝐞𝐫.
Researchers at King's College London reviewed clinical trials using focused ultrasound with intravenous microbubbles to non-invasively and reversibly open the blood-brain barrier in glioblastoma patients, examining how the technique helps deliver chemotherapy past a barrier that has long limited treatment for this deadly cancer.
🔍 𝐖𝐡𝐚𝐭 𝐭𝐡𝐢𝐬 𝐫𝐞𝐬𝐞𝐚𝐫𝐜𝐡 𝐢𝐦𝐩𝐥𝐢𝐞𝐬:
The blood-brain barrier has always been framed as an obstacle that drug design has to route around — different formulations, different delivery vehicles. This review consolidates evidence for tackling the problem at the barrier itself: temporarily and safely opening it on demand, then letting it reseal.
💡 𝐊𝐞𝐲 𝐭𝐚𝐤𝐞𝐚𝐰𝐚𝐲𝐬:
🎯 FUS paired with systemically administered microbubbles creates a non-invasive, targeted, and reversible way to increase BBB permeability at a precise location
🎯 GBM remains difficult to treat despite surgical resection, chemotherapy, and radiotherapy — largely because the BBB blocks adequate drug concentrations from reaching the tumor
📌 𝐖𝐡𝐲 𝐭𝐡𝐢𝐬 𝐦𝐚𝐭𝐭𝐞𝐫𝐬:
If FUS-mediated BBB opening becomes a reliable clinical tool, it could meaningfully expand the range of therapies — chemotherapy, immunotherapy, gene therapy — that can actually reach brain tumors at effective concentrations, rather than being blocked at the barrier before they arrive.
🔗 𝐑𝐞𝐚𝐝 𝐌𝐨𝐫𝐞: https://t.co/iun7XcVAxh
#Neuroscience #BrainCancer #Glioblastoma #NeuroTech #DrugDelivery #Anthriq
the team at @anthriq is building a 13-channel wireless EEG headset with dry motor-adjusting electrodes and onboard FPGA signal processing. genuinely very cool. would love to meet Siddhant, Deepansh and the team in Bengaluru.
Aerospace and defence is where propulsion, sensors, autonomy, materials and manufacturing all have to work together under unforgiving constraints.
Excited to nerd out about it at our second M33 meetup.
https://t.co/NpesSeh2vR
Modern browsers don't need a cookie to track you anymore.
You can perform a scary amount of fingerprinting without it too including location, time, ISP, IP Addresses, Google Ads ID and more.
and I built a fun website just showcasing a part of it
https://t.co/sWEupbh99L
after the success of our last meetup, we are hosting another one for deeptech builders of bombay, this time in aerospace and defense. if you are building satellites, rockets, ramjets, armed uav/ugv, or weapons; come hang out with us :)
https://t.co/b66UEfQliV
Manastu’s VYOM-2U is rated at 1.1 N, >250 s Isp and >1,200 N·s total impulse.
On a 20 kg spacecraft, that is roughly 60 m/s of delta-v before losses: useful for orbit correction and collision avoidance, without hydrazine’s handling burden. https://t.co/32pda5kubq
@GalaxEye targeted shrinking 400 MB of raw SAR data to <1.5 MB onboard POEM-4: ~267x.
That moves processing from ground to orbit. One radio link can return more scenes per pass, cutting delivery time for flood, ship and border monitoring.
https://t.co/32pda5kubq