Assistant Professor of Pathology & Cytopathology at Uni of Mississippi Medical Center
Alumnus: SIMS, SUNY Downstate, UPMC
Traveler, Photographer & nature-lover!
Some aspects of sarcoidosis that many pathologists are not aware of. Presented by me at USCAP24.
1- Necrosis of variable extent has been reported in as many as 39% of cases. Foci of necrosis are usually small but may be large in some cases.
2- Granulomatous vasculitis is reported in two thirds of open lung biopsies and in 100% of autopsy lungs. Rarely seen in transbronchial lung biopsies. Not specific for sarcoidosis.
3- Nodular sarcoidosis (NS) is a diagnosis based on chest X-ray in which there are 1 or more lung nodules that may simulate the appearance of metastatic neoplasm. 1.5%-4% of sarcoidosis cases present in this manner.
4- Necrotizing sarcoid granulomatosis (NSG), first described by Liebow in 1973, is characterized by confluent granulomas with necrosis that may be extensive, and granulomatous vasculitis.
5- Review of worldwide literature in the 4 decades since Liebow described NSG strongly indicates that NSG is a part of the spectrum of lesions seen in sarcoidosis and that it is essentially identical to NS.
6- In sarcoidosis there is a continuous spectrum of necrosis ranging from none to minimal to extensive.
7- NSG as a diagnostic term should be replaced with "sarcoidosis with NSG pattern" or similar.
Honored to present
“navigating pitfalls in thyroid cytology”
at the 2024 Tristate Pathology Conference
@UMMC_Pathology in full strength.
@Pathologists@AghaWajdan
HAPPY MATCH DAY!!!! Welcome our new Pathology Residents!! We're so excited to welcome you to our Pathology family !! #pathtwitter#Match2024#PathMatch24
PSAMMOMA bodies (although quite specific when combined with cytomorphology) are rarely seen on FNA smears of “Papillary Thyroid Carcinoma”. This completely intact one is the best that I have seen over the years.
HCGs (Hyperchromatic Crowded Groups) are always a challenge to interpret in GYN cytopogy. Trick is to look at the edges of the fragments at higher magnification. The diagnosis here - HSIL. (SurePath LBP)
A cell block preparation from a lung nodule FNA in an older man with history of multiple myeloma. Notice the variably sized structures in the H&E stain, which are highlighted by GMS stain. Mucicarmine stain demonstrates the mucin capsule. Diagnosis? #CytoPath
Fantastic presentation by @PathPro and @SMonaco3 at #ASCyto23: Ten Terribly Tough Touches (4Ts): Lessons learned from rapid on-site evaluations (ROSEs) of touch preparations in small biopsies