Agologist

Creator/Co-Creator

[Agologist @Agologist]

I've been SPOT ON 🎯🎯🎯 regarding the role and the position of Mahmoud Ahmadinejad 👇

[Yashar Ali 🐘 @yashar]

BREAKING

In a story bylined by several of The New York Times’ top national security reporters, including Israel-based reporter Ronen Bergman, the Times reveals a quixotic and shocking Israeli-engineered plan to free Mahmoud Ahmadinejad from house arrest and install him as Iran’s leader.

An Israeli strike on Ahmadinejad’s home in Tehran was not primarily meant to kill him. It was allegedly designed to kill the IRGC guards holding him under house arrest and free him.

The plan apparently went sideways almost immediately. Ahmadinejad survived, but after the “near miss,” he became disillusioned with the regime-change plan. He has not been seen publicly since, and the Times says his current condition and whereabouts are unknown.

Ahmadinejad had recently traveled to Guatemala and Hungary — both countries with close ties to Israel.

The article also notes that Ahmadinejad had returned from Budapest just days before Israel began attacking Iran the previous June, and that once the war broke out, he kept a strangely low profile for someone who had spent years presenting Israel as Iran’s central enemy.

Full Story: https://t.co/y71ABoXs4Q

[Molly O’Shea @MollySOShea]

Data centers in space are a "no brainer."

SpaceX's 1st employee Tom Mueller (@lrocket) on @elonmusk's plan to move compute into space:

"It makes the most sense of anything to move to space. All you need as an input is power, and all you have as an output is data."

"You move it to space, you have all the power you would ever need, and you transmit that data back down on a terawatt laser beam—it's solved. It's just so simple."

[Phil Labonte 🇺🇸 @philthatremains]

Emma is the personification of every awful liberal/progressive trope ever uttered.

[Agologist @Agologist]

@realMaalouf Copycat:

https://t.co/He0wvl5rRQ

[Agologist @Agologist]

@realMaalouf Copycat:

https://t.co/He0wvl5rRQ

[Wendy Rogers @WendyRogersAZ]

Federal government must act NOW to stop CA’s election theft! DOJ—launch immediate criminal probe into unsecured mail-in ballots with ZERO chain of custody and Democrat-only Dropbox dumps. Bass & Raman magically surge while rightful winner Spencer Pratt gets robbed. Subpoena everything! #StopTheSteal

[Wendy Rogers @WendyRogersAZ]

FBI—open RICO investigation into CA Dem election machine. Unsecured dropboxes, mail ballots without custody chain, and every dump favoring Bass/Raman over Spencer Pratt screams organized crime. Feds: Raid counting centers, preserve evidence, stop the steal before certification!

[Dr Walid Phares @WalidPhares]

My interview on @NEWSMAX on the "army" the Islamic regime in Iran has deployed inside the US Homeland.

[Political Polls @PpollingNumbers]

🔵 Democrats are projected to shut Spencer Pratt out of the Los Angeles mayoral runoff (Polymarket)

[Agologist @Agologist]

FWIW- In 2018, Tim Draper @TimDraper and his team collected more than the required number of signatures, over 800,000 if I remember accurately, to put CAL 3 on the ballot to split California into three states. The Supreme court of California, 7 people, then just tossed the prop. 7 "Experts", against the will of over 800k people ... "Democracy/democracy" is meaningless in California.

[Agologist @Agologist]

FWIW- In 2018, Tim Draper @TimDraper and his team collected more than the required number of signatures, over 800,000 if I remember accurately, to put CAL 3 on the ballot to split California into three states. The Supreme court of California, 7 people, then just tossed the prop. 7 "Experts", against the will of over 800k people ... "Democracy/democracy" is meaningless in California.

[C3 @C_3C_3]

Spencer Pratt got 0 out of 24,000 votes in a late night LA ballot drop.

0/24,000

A guy getting around 30% support got 0 out of 24,000.

Astronomically small probability of happening.

Impossible.

California no longer even hides it.

Doors need to be kicked in.

[Defiant L’s @DefiantLs]

Rep. Ro Khanna on Platner’s Nazi tattoo: "He said it was a mistake… I guess I have a view of redemption."

I can't believe this. The gaslighting is unreal.

[Ruxandra Teslo 🧬 @RuxandraTeslo]

China is winning the drug discovery race. There's no better example of this than multiple myeloma.

https://t.co/YaJSUquRoa

It's one of the most painful cancers, destroying bone from within. For decades, patients endured cycles of brutal treatment and relapse. Then came Carvytki: a one-time CAR-T infusion that appears to cure some patients who have failed multiple treatments.

Its development story, beginning in 2016, was an early signal of a shift now making headlines: the US is losing biotech dominance to China. Though the foundational science was largely American, a nimble Chinese company moved faster with a better molecular engineering idea.

Unless the US addresses clinical-trial bottlenecks slowing early in-human data, more breakthroughs will be developed elsewhere, weakening the ecosystem American biopharma depends on.

Some key points from my article for @WorksInProgMag, with my friend Amol Punjabi, of @EvidenceOpen:

1) Multiple myeloma is not only extremely painful in and of itself, but also one of the most brutal cancers to treat. As first-line therapy, patients endure four drugs simultaneously, then a stem cell transplant, followed by continuous maintenance therapy. And most still relapse, with each treatment round carrying worse chances.

2) A drug called Carvykti, approved in 2022, is changing the treatment landscape. Carvytki acts as a single, one-time infusion. It's a CAR-T therapy, part of a new wave of transformative immunotherapies: made from the patient's own immune cells and reprogrammed to hunt cancer. In patients who had already failed 4+ other treatments, 33% were still disease-free after 5 years. The results as earlier line therapy look even more promising.

3) Most of the foundational science was American. Decades of CAR-T research, and in 2013 the NCI showed BCMA-targeted CAR-T cells could kill myeloma in the lab.

4) But the drug that ultimately changed myeloma, Carvytki, originates from China. Carvytki beats Abecma (the American CAR-T for myeloma) by a wide margin: 36 months of progression free survival in heavily pre-treated patients versus Abecma's 9 months.

5) In 2016, Legend Biotech was just beginning clinical trials. This was the same year the American team was publishing their first-in-human results. Legend started later, but moved faster. Clever engineering and China's ability to get drugs into humans quickly gave them the edge. Large American biopharma J&J ended up striking a deal with Legend and developing the therapy.

6) Never underestimate the llama: US-developed Abecma used mouse antibody fragments to target BCMA. Chinese startup Legend used llama nanobodies instead. These are smaller, more stable and bind more cleanly to BCMA. The usage of llama as opposed to mice antibodies is what is believed to lead to Carvytki's superior efficacy.

7) In retrospect, Carvytki should have been an early warning. China is winning the drug discovery race through deliberate policy. Their first-in-human clinical trials can launch in 6 months vs 18+ months in the US, letting them iterate faster between lab and clinic. The @nytimes recently reported that ~50 percent of major drug deals this year involve Chinese-origin drugs, up from nearly zero a decade ago.

8) The US still leads in late-stage development, as shown, but the pipeline feeding it is increasingly Chinese. The worry is that this will mirror what happened in solar, batteries, and EVs, where early-stage dominance eventually became control of the entire chain.

9) A proposal to streamline early stage trial regulatory requirements to keep the US competitive has made it into the President's 2027 budget for the FDA. But Congress has to act to make it a reality.

[David Sacks @DavidSacks]

Signs you might be trying to get your frontier AI lab nationalized:

You compare it to nukes… threaten half of white-collar jobs… warn recursive self-improvement could end humanity… then race ahead anyway.

In other words, you want the government to save us from… you.

[Agologist @Agologist]

The point is not whether something is AI-generated or not. The point is blurring the difference, until there's no difference.

[Alex Jones @RealAlexJones]

Happy 96th birthday to the TRUE American ICON, Clint Eastwood! And of course Sylvester Stallone is another American icon,and I couldn’t imagine a better person to present Clint his cake.

Truth is cooler than fiction!!

[Agologist @Agologist]

@walterkirn That's exactly why they're used as political bait, because jealousy is one hell of a drug.

[Agologist @Agologist]

@walterkirn That's exactly why they're used as political bait, because jealousy is one hell of a drug.

[Walter Kirn @walterkirn]

If you knew how many billionaires have one foot and two toes out of the US you would be shocked. And then you would be mad at the billionaires. Instead of seeing them for what they are. Leading indicators. Doing what you would do if you had their info and their options.

[Agologist @Agologist]

@AgesInsight

[Agologist @Agologist]

Objectively speaking, there's absolutely no way to determine when AI becomes/became AGI. Who's going to determine that? A human with general intelligence of all humans? Scientists? Priests? Bernie Sanders? The Pope? Podcast bros? ... It'll take an AGI to recognize an AGI, for the same reason that it takes a Philosopher to recognizes a Philosopher. Many would argue and claim otherwise, because the lack of ability to determine certainty is one hell of a grift. Just look at religions, or "The News".

[Agologist @Agologist]

If fire was being discovered now, politicians would be passing laws to control it, religions would be making Moral arguments to limit it, and the public would be afraid of the unknown. Yet, fire would warm up as it would burn down without discrimination.

[Agologist @Agologist]

Objectively speaking, there's absolutely no way to determine when AI becomes/became AGI. Who's going to determine that? A human with general intelligence of all humans? Scientists? Priests? Bernie Sanders? The Pope? Podcast bros? ... It'll take an AGI to recognize an AGI, for the same reason that it takes a Philosopher to recognizes a Philosopher. Many would argue and claim otherwise, because the lack of ability to determine certainty is one hell of a grift. Just look at religions, or "The News".