Dong-Hun Lee

Assistant Professor
Wildlife Health Laboratory
College of Veterinary Medicine, Konkuk University.
Views are my own.

[ASM @ASMicrobiology]

As climate risks accelerate, infectious disease threats are intensifying. A new ASM–AGU report outlines the science needed for better disease detection, attribution and preparedness.📘https://t.co/SgayD76Tct
@theAGU

#ClimateScience
#InfectiousDiseases #Microbiology

[keno_st @st_keno]

1/5

Introducing SimPlot-CL! 🧬
Recombination plays an important role in viral evolution. Similarity plots are a great way to visualize recombination patterns, but generating them across many genomes can be cumbersome.

📂 https://t.co/U2P1rLRn8s

[Dong-Hun Lee @aivndv]

I'm excited to announce the publication of our latest paper in @Virus_Evolution : "Wild birds drive the introduction, maintenance, and spread of H5N1 clade 2.3.4.4b high pathogenicity avian influenza viruses in Spain, 2021–2022". https://t.co/UJ5vKh9SRE
#influenza #H5N1

[Stephen Turner 🦋 @stephenturner.us @strnr]

Claude scientific skills 🧬🖥️🧪
https://t.co/F3rvaYGFRa

🧬 Bioinformatics & Genomics
🧪 Cheminformatics & Drug Discovery
🔬 Proteomics & Mass Spectrometry
🤖 Machine Learning & AI
🔮 Materials Science & Chemistry
📊 Data Analysis & Visualization

[Mahmoud Naguib 🦠👀 @EyesOnViruses]

Easy pipeline to trace reassortment among influenza A viruses.
Revealing Reassortment in Influenza A Viruses with TreeSort https://t.co/8thhKJN0qj

[Nature Reviews Microbiology @NatureRevMicro]

New online! Clinical metagenomics for diagnosis and surveillance of viral pathogens https://t.co/X9ceopQLos

[Dong-Hun Lee @aivndv]

New paper out! The presence of mammalian adaptation markers and high binding affinity of Y280-lineage H9N2 viruses to human-type sialic acid receptor raise a concern on zoonotic potential. https://t.co/uOm70PaexT

[Michelle Wille @DuckSwabber]

First documented case of H5N1 HPAI in a wild mammal in South Korea: leopard cat. Clustered with clade 2.3.4.4b H5N1 HPAIVs isolated from wild birds in South Korea, 36 mammalian adaptation markers
👉https://t.co/0lxQwfchGr

[Dong-Hun Lee @aivndv]

Even a small proportion of mammalian-adaptive mutations can quickly become dominant as the virus transmits. It is crucial to monitor the presence of minor mammalian-adaptive variants using deep sequencing to assess the potential risk of transmission to mammals, including humans.

[Dong-Hun Lee @aivndv]

New paper out! The PB2-E627K mutation in clade 2.3.4.4b H5N1 HP avian influenza was rapidly selected following a single infection in mice, transmitted, and reached nearly 100% in direct-contact mice.

https://t.co/aecQiyhgBw

[Dong-Hun Lee @aivndv]

@noemielefrancq @Nature Very nice study! Congratulations. I am preparing a Korean H9N2 dataset for this phylowave analysis😀

[Dong-Hun Lee @aivndv]

This finding underscores the importance of ongoing wildlife disease surveillance and research to understand and mitigate the risks of zoonotic diseases. Let's continue to support efforts in wildlife conservation and disease surveillance.

[Dong-Hun Lee @aivndv]

For the first time, a wild mammal in South Korea has tested positive for H5N1 clade 2.3.4.4b highly pathogenic avian influenza (HPAI). An endangered leopard cat (Prionailurus bengalensis) was found near a reservoir in Hwasun County, Southern part of Korea on March 18.

[Dong-Hun Lee @aivndv]

While this raises concerns about the potential for HPAI to spill over into other species, the risk remains low due to the solitary nature of leopard cat. No further cases have been detected so far.

[Dong-Hun Lee @aivndv]

@DuckSwabber Thanks for your efforts. It is very helpful for me to get to know new publications in a timely manner.

[Dong-Hun Lee @aivndv]

A snowman built by vet school students of Konkuk University, Korea
건대수의대 눈사람 수준 🤣

[Cell Press @CellPressNews]

Genetic tracing at the Huanan Seafood market further supports an animal origin to #COVID19.

Learn more in @CellCellPress:
https://t.co/rd4ZbhZIS0

@MichaelWorobey
@Sorbonne_Univ_ Florence Débarre
@scrippsresearch Kristian Andersen

[Florian Krammer @florian_krammer]

'Virology—The next fifty years' - a perspective by Eddie Holmes, @GoodrumVirusLab and myself in Cell

https://t.co/jOJWY6BPqI

[EID journal @EIDjournal]

#H5N1 virus was detected in dead seals on Tyuleniy Island in eastern Russia, in the Sea of Okhotsk. Viruses isolated from the seals belong to clade 2.3.4.4b and are closely related to viruses detected in the Russian Far East and Japan in 2022–2023.
https://t.co/xLmFgBEQs7