Takeda commits up to $600M to Insilico's https://t.co/GaDOB39vGe for drug discovery—the pharma giant's third major AI platform deal in months, signaling a strategic shift toward outsourced AI-driven R&D. #AI#DrugDiscovery#Pharma
Roche's divarasib becomes first KRAS G12C inhibitor to beat approved rivals in head-to-head Phase III trial, showing superior PFS and OS in second-line NSCLC. A potential game-changer for the ~14% of patients with G12C mutations. #Oncology#KRAS#NSCLC
Nippon Shinyaku opts into Elixirgen's full-length dystrophin mRNA (EXG-7001) for DMD—a mutation-agnostic approach distinct from exon-skipping and gene therapy. IND filing imminent. #DMD#mRNA#RareDisease
Ipsen acquires Kartos for navtemadlin, an oral MDM2 inhibitor in Phase III for myelofibrosis. The p53-reactivating combo therapy targets ruxolitinib-suboptimal patients, with POIESIS data expected 2027. Deal valued up to $1.75B. #Oncology#Pharma#Myelofibrosis
Rare reversal: CHMP backs trofinetide for Rett syndrome after initial rejection, paving the way for the EU's first approved pharmacological therapy for the rare neurological disorder. #RareDiseases#EMA#Pharma
Remix Therapeutics goes public via Passage Bio reverse merger, securing $100M PIPE. Lead asset REM-422 showed 43% ORR in ACC patients at ASCO 2026—a cancer with zero approved systemic therapies. Trading as RMTX on Nasdaq. #Biotech#Oncology#ClinicalTrial
Novartis commits up to $1.9B to Antares Therapeutics' covalent chemistry platform targeting undruggable oncology candidates. One of the largest upfront payments for a discovery-stage oncology collaboration this year. #Biotech#Oncology#DrugDiscovery
Merck KGaA to acquire Bio-Techne for $11.3B—its largest deal ever. The Minneapolis biotech firm's recombinant proteins, antibodies & immunoassay platforms strengthen Merck's life sciences dominance. Deal closes late 2026/early 2027. #Biotech#M&A #LifeSciences
Oblenio Bio closes $62M Series B to advance LBL-051, a tri-specific T-cell engager targeting CD19/BCMA/CD3 for autoimmune disease. First-in-human study expected to launch this year. #Biotech#Immunology#ClinicalTrial