How do antibodies against PfRIPR act to impede erythrocyte invasion? In our latest study, we isolate and structurally characterise a panel of human antibodies and the growth inhibitory antibody RP.012, revealing an unexpected story of synergy and antagonism.
New Cell paper from the team that discovered glymphatic clearance (how your brain removes waste during sleep).
Sleep hours DIDN'T predict brain cleaning. Neither did REM or deep sleep.
They found what actually matters - and why some sleeping pills might undermine it 🧵
PhD contract available in the @icmabCSIC in my group to work on the synthesis and characterization of New Photosensitisers for Panchromatic Photoisomerization. Retweets appreciated. Candidates please contact me directly.
Delighted to share the final version of Richard Zhou's study on how the CD163 scavenger receptor cleans up after toxic haemoglobin spills out from our blood cells. An amazing grabber mechanism!
https://t.co/T4hjaHnedb
How the #malaria#parasite evades the immune system… and how the human body fights back: Sam Chamberlain and Matt Higgins @Oxford_uni make ground-breaking discovery, just published in @Nature. Read more: https://t.co/1jdS4twJCX
@nawsad_alam presented our structure-guided design of RH5top, our latest blood stage-malaria vaccine immunogen in talk and poster at the Malaria Gordon conference. The culmination of many studies from the lab and doing well in pre-clinical testing! More soon.
New science from Richard Zhou... When our blood cells lyse, they release haemoglobin, which is dangerous to our body. We detoxify this by binding it to a serum protein, haptoglobin and taking it up into macrophages, using the receptor CD163. Richard showed how CD163 works!
Congratulations to Dr Kuang-Ting! Expert on the gametocyte surface and structural characteriser of transmission-blocking vaccine immunogens. I’m a proud supervisor!
The final version of our paper on PfRH5-targeting antibodies from people naturally infected with malaria is now out in Cell. Pioneered by @Lewreate7, @andrewcooperajr and Josh Tan, who identified these antibodies. It was a pleasure for @brendanfarrell and I to contribute.
Over the moon to share that this has now been published in @Nature! Congrats to everyone involved! Check it out here - https://t.co/QlxblnVV6Z
Or watch us chat about it here - https://t.co/GVz8H07vgq
Congratulations to Dr @TPholcharee! Pioneer of structural biology on important vaccine immunogens used to target the malaria parasites. We are very proud of him. A Poy-aneer!
Bales de goma prohibides, cops de porra delictius, càrregues contra gent asseguda, furgonetes fent carrusels, gasos lacrimògens… Són actuacions policials denunciades per les associacions pro drets humans l'última setmana. Obrim fil
https://t.co/P76uNZBPhF #SentènciaProcés
Donna Strickland, who received her PhD in optics from Rochester in 1989, is the first woman to win the Nobel Prize in Physics in 55 years. Congratulations, Dr. Strickland! #meliora