Ash

✨🌱organically introverted🌱 ✨
|CHN| focused ➡️cellular energy ⬅️
Book here: ✝️🇺🇸

[Ash @AncientInstinct]

This isn't theoretical-NHANES cohort data reveals that high red blood cell folate levels driven by synthetic folic acid (your government mandated enriched foods) are associated with a 🤯32% increase in cardiovascular mortality and a 😱25% increase in all-cause mortality in older adults with preexisting heart disease!
This excess synthetic folate in your food (and supplements+energy drinks) competitively blocks MTHFR and DHFR, creating a drug-like "pseudo-MTHFR deficiency" in people with COMPLETELY NORMAL GENETICS.
Leading killer in the US?
HEART DISEASE
STOP FORTIFYING OUR FOOD
🔥Folinic acid for heart disease🔥
Study here:
https://t.co/qPn339ltlW

[Ash @AncientInstinct]

@snack_butt_ Last time i tried all my doctor/hospital records were erased

[Ash @AncientInstinct]

@DaneDe4orest Dane this is pretty awesome to me no ones ever showed me this. Husband controls 99.99999 percent of finances, im in idiot world. Excuse me while i get a little excited.

[Ash @AncientInstinct]

@rhirhiarhii If i make myself sit in front of my red+near infared light for 20 min am 20 min pm this feeling completely goes away. Going now. Lol

[Ash @AncientInstinct]

@DaneDe4orest Research so far "how do i put my money on a stock" lol

[Ash @AncientInstinct]

@DaneDe4orest Well that sounds like a solid plan then. Thank you

[Ash @AncientInstinct]

@DaneDe4orest WHICH THING. Lmao🤣

[Ash @AncientInstinct]

@Zenfrog4 A2 as well?

[Ash @AncientInstinct]

@jack_schroder_ Liposomal!

[Ash @AncientInstinct]

@hot_cocoa_girl Its because we left our bodies we cant feel anything anymore, numb, literally stuck in fear. Usually accompanied by drug/alcohol use in my opinion.

[Ash @AncientInstinct]

@1True_American_

[Ash @AncientInstinct]

@JillSolvolver Theyre making it easy to find sell outs. What kind of person with so much public influence thinks its a good idea to push a new drug ever? New drug? Wait dude. U wait and watch.

[Ash @AncientInstinct]

This guy knows. (Or girl)

[Gut First @GutFirstHealth]

Biofilms are becoming hardier than ever, meaning your basic NAC and serrapeptase biofilm busters are barely cutting it,

Even worse previous failed antimicrobial or antibiotic attempts make these even harder by upregulating resistance genes.

So what on earth can you do?

My approach? Hit em where it hurts, every angle possible.

- Serrapeptase or Nattokinase for dissolving biofilm proteins

- N-acetyl Cysteine to break down the repellent disulfide bonds

- EDTA and Lactoferrin to cut off and destabilise the mineral sources they need to build

- Monlaurin to disrupt the lipid membranes and prevent adherance

- Quercetin to lower gene expressions that form biofilm and resistance in the first place

- Bismuth thiols to penetrate the biofilm and reduce their exopolysacharide armour by up to 90%

- Alpha-amylase to dissolve sugars in the biofilm matrix

You literally don't give biofilms a chance when you hit them from all angles of their existence,

Pair with a decent antimicrobial stack and it will be wildly more effective.

Going to throw a link to my personal progress tracking tool in the comments, if you're not sure if what you're doing is working or just want to track and course correct it'll make the whole process vastly easier.

[Ash @AncientInstinct]

@GutFirstHealth Great post

[Ash @AncientInstinct]

They do contain folic acid if its GMO is garbage! Buy USDA organic. Grow it if u can. Gmo is useless. And usually people that are "deficient in b vitamins" (99 percent of us-dont be fooled) also have comprimized gut health/poor microbiome- dont just shove a shitload of greens in his mouth. ❤️

[Ash @AncientInstinct]

Calcium folinate=folinic acid= active form of b9= why the fuck did our government make this so difficult for us? Because disease is easy when you take away the essential nutrient that helps your body make and repair DNA, produce healthy red blood cells, and support normal cell growth daily.
They know

[Ziv @biohackerziv]

Calcium Folinate + Adenosylcobalamin + TMG > Methyl-Folate and Methyl B12.

"Oh, but I have MTHFR polymorphism"

Even then.

Here's why and science behind 👇

The dogma that MTHFR mutations (C677T/A1298C) require mega-dosing Methylfolate (5-MTHF) and Methylcobalamin (Methyl-B12) is driving widespread ADHD, insomnia, OCD, etc.

A sluggish MTHFR enzyme does not want to be carpet-bombed with exogenous methyl groups.

The physiologically superior triad that outclasses the methyl stack—even in homozygous MTHFR variants—is:

Calcium Folinate (Folinic Acid) + Adenosylcobalamin + Trimethylglycine (TMG)

This framework restores nucleotide synthesis, powers mitochondrial respiration, and clears homocysteine through hepatic bypasses while allowing cells to regulate methylation on demand.

The 5-MTHF Trap: Starving DNA & Spiking Adrenaline

• The Irreversible Checkpoint:

MTHFR irreversibly shunts folate into 5-MTHF. Once committed, it can only remethylate homocysteine via Methionine Synthase (MTR). It cannot reverse.

• Genomic Starvation:

Flooding 5-MTHF bypasses upstream pools, starving de novo synthesis of purines (adenine/guanine) and thymidylate (dTMP via TYMS). RNA synthesis, DNA repair, and red blood cell division stall.

• The COMT Adrenaline Crash:

Rapid SAMe spikes from unbuffered 5-MTHF hyper-activate PNMT, shunting norepinephrine into adrenaline.

In slow COMT phenotypes, accumulating catecholamines cannot be cleared, triggering acute adrenergic anxiety and executive collapse.

Calcium Folinate: Demand-Driven Folate Flux

• Upstream Entry (MTHFS):

Converted by MTHFS directly into 5,10-methenyl-THF, which effortlessly feeds 10-formyl-THF (purines/ATP) and 5,10-methylene-THF (thymidine for DNA stability).

• Physiological Mass Action:

Folinate pushes adequate substrate through a sluggish MTHFR enzyme via mass action strictly on demand. You get complete genomic repair without dumping unbuffered methyl donors into the central nervous system.

Adenosylcobalamin: Mitochondrial ATP Over Synaptic Noise

• The True Tissue B12:

While Methyl-B12 acts only in the cytoplasm, Adenosylcobalamin (Dibencozide) is the exclusive B12 cofactor for mitochondrial Methylmalonyl-CoA Mutase (MUT).

• Krebs Cycle Flux:

MUT converts L-methylmalonyl-CoA into Succinyl-CoA, driving the citric acid cycle, ATP production, and odd-chain fatty acid catabolism.

• Regulated Shunting:

Via the CblC pathway, the cell utilizes it for mitochondrial energy while routing a controlled fraction into cytosolic Methyl-B12 strictly as required—preventing synaptic methyl overload.

TMG: The Folate-Independent Homocysteine Bypass

• The BHMT Highway:

In the liver and kidneys, Betaine-Homocysteine S-Methyltransferase (BHMT) directly remethylates homocysteine to L-methionine by consuming TMG.

• Zero Folate/B12 Dependency:

Clears systemic homocysteine and generates native SAMe without requiring MTHFR or the folate cycle.

• The Inhibitory Buffer:

TMG metabolizes into DMG and then Glycine—an inhibitory neurotransmitter that quenches excess NMDA glutamate excitotoxicity and shields against central anxiety.

• Mandatory Cofactors:

Riboflavin-5-Phosphate (Active B2, 25mg to 50mg):

Generates FAD, the obligate prosthetic cofactor that physically stabilizes the MTHFR enzyme.

Pyridoxal-5-Phosphate (Active B6, 25mg):

Drives downstream Cystathionine Beta-Synthase (CBS) to shunt excess homocysteine into glutathione and taurine.

Magnesium (300mg to 400mg): Powers ATP-dependent kinases and COMT clearance.

[Ash @AncientInstinct]

@Kaya_health_x Sure does!!!!! Liposomal liposomal if you can!

[Ash @AncientInstinct]

Methylfolate or folinic acid. NOT folic acid. Dont let them. Folic acid is synthetic and not bioavailable. Dog shit. Not only useless but dangerous and causes hell inside your body- since we cannot use it, your body will raise homocysteine (vascular health marker, think heart attack and stroke when it goes up)-even with perfectly healthy people without any genetic SNPS. Can and will cause cognitive/behavioral/ mental health issues for sure and if your female on birth control get ready for your pcos and pray you dont get a blood clot. Half our population has MTHFR which makes this so much worse-they dont know it because most docs dont "do genetics" and they refuse to test. Some of us get lucky and figure it out. Must advocate for yourself, cut out the folic acid and enriched fortified shit and focus on real food. Throw it out if u see the word enriched or folic acid on the package. Folic acid is poison to EVERYONE. They know

[Ash @AncientInstinct]

@dantbedenied Omg pavement

[Ash @AncientInstinct]

@QuoteJung Oh this is GOOD