Tim Curry, who soared to fame in the ‘70s as the flamboyant star of“The Rocky Horror Show," has died at 80.
A cause of death was not immediately available, though Curry had suffered from several health issues since having a severe stroke in 2012.
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🚨 BREAKING NEWS: The first-ever personalized mRNA cancer vaccine has successfully cleared Phase 3 clinical trials.
Pharmaceutical giants Merck and Moderna announced that their experimental mRNA cancer vaccine, intismeran, achieved positive results in its late-stage Phase 3 trial. Designed to treat high-risk melanoma patients whose tumors had been surgically removed, the individualized vaccine was paired with the immunotherapy drug Keytruda.
The combination met its primary and secondary endpoints by significantly reducing the risk of the cancer returning or spreading to other organs compared to using Keytruda alone. This milestone marks the first time a personalized mRNA-based cancer therapy has successfully cleared the final phase of clinical testing.
The customized therapy works by genetically sequencing a patient's unique tumor and utilizing mRNA technology to instruct their immune system to target up to 34 distinct cancer markers. Rather than a preventative vaccine, it functions as a highly targeted therapeutic tool tailored to a patient's exact cellular blueprint. With positive safety profiles and mostly minimal side effects reported, researchers are optimistic that this breakthrough could soon be adapted to combat other aggressive diseases like lung, bladder, and pancreatic cancers. The companies plan to present the full data at an upcoming medical meeting and engage with regulatory authorities to seek accelerated approval.
source: Merck & Co. and Moderna. (2026). Phase 3 INTerpath-001 Trial of Intismeran Autogene Plus KEYTRUDA.
Global icon and humanitarian, Dolly Parton, known to the world as a beloved singer, songwriter, philanthropist, actress, playwright, and author died peacefully today in Nashville, Tennessee. She was 80 years old.
Dolly is preceded in death by her beloved husband of 59 years Carl Thomas Dean (1942 – 2025), her mother Avie Lee Caroline Owens (1923 – 2003), and father, Robert Lee Parton, Sr. (1921 – 2000).
A rhinestone life that shone bright enough for the world to see, Dolly will forever stand as an inspiration not only through her timeless music and prolific songwriting, but also her wit, warmth, and kindness that made us all feel like family. Dolly Parton’s legacy is one of love, compassion, and resilience. With a seven-decade career, she inspired multiple generations of artists and fans with her music and an unwavering commitment to making the world a better place. Her songs will continue to resonate with people of all ages, and her philanthropic work will have a lasting impact.
At Dolly’s request, a small, private service will be held for immediate family. Dolly’s fans and friends from around the world are encouraged to pay tribute to Dolly on social media by tagging @DollyParton or by leaving a message at https://t.co/cLu9I7M2wC
In lieu of flowers the family asks for donations to be made to Dolly Parton’s Imagination Library at https://t.co/arzrqInqJA
@SantaFaustynaES Buenas tardes muchísimas gracias , pido por el milagro este diciembre 2026 para mi familia y por mi , por nuestras necesidades y por las hermanas de nuestra señora de la misericordia , bendiciones 🙏🏻🕊️
The Blessed Virgin Mary, assumed into the glory of heaven, is a sign of hope and consolation for the entire People of God. For this reason, I wish to invoke her maternal intercession today on behalf of those communities that are in particular need of consolation and of renewed hope. My thoughts go out to our brothers and sisters in the Holy Land, which is also, par excellence, the Land of Mary. My thoughts also go out to the Ukrainian and Russian peoples, both of whom are united by their filial devotion to the Holy Mother of God, and to Christians who suffer discrimination or even persecution.
Fidel Castro was a complete failure at everything except destroying Cuba and impoverishing, jailing and murdering his own people
I strongly suggest that anyone tempted to try and follow his example should carefully reconsider, because if they do they would be dooming themselves to failure as well
Doomsday arrives December 18th.
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