Anne Mardy, MD

MFM/Geneticist at @uthealthaustin @dellchildrens | Alum of @Stanford @ColumbiaPS @ColumbiaWomens @UCSF_ObGynRS

[Anne Mardy, MD @annehmardy]

Loved writing this with @pndxdoc “Diagnostic testing after positive results on cell free DNA screening: CVS or Amnio?” @UCSF_ObGynRS
⁦@ISPDHQ⁩ https://t.co/Lc7Bs6shgQ

[Magda Sanz @masancor07]

About the new indication for in utero repair of #gastroschisis:
Here’s the eligibility criteria

[Bobby Brar @DrBobbyBrar]

Heterozygote status in certain genes on carrier screening can have implications for maternal disease risk #smfm23 @MySMFM #mfmgenetics

[Anne Mardy, MD @annehmardy]

@MichaelMAzizMD1 Best meme award!

[Anne Mardy, MD @annehmardy]

@rnickburns_md

[Anne Mardy, MD @annehmardy]

ALPS long term 6 year f/u: no difference in childhood neurodevelopmental outcomes, even if you just look at those born >37 wks
@MySMFM #SMFM23 @drcynthiagyamfi

[Anne Mardy, MD @annehmardy]

International RCT: azithro in labor (14,590) vs placebo (14,688). Decreased maternal sepsis/death. NNT 125. Stopped early for maternal benefit. No difference in neonatal outcomes. @atitapatterns @MySMFM #smfm23

[Anne Mardy, MD @annehmardy]

@ariannacassidy @TimWenWhereWhat Seems like a collusion…

[Anne Mardy, MD @annehmardy]

RCT from France: stopping oxytocin during active labor (6cm) in 1192 pts vs 1175 controls. No difference in neonatal morbidity, mode of delivery, C/S indications. Control group shortened labor by 47 mins @MySMFM #SMFM2023

[Anne Mardy, MD @annehmardy]

Israel RCT: ampicillin (62) vs cefuroxime (62) w roxithromycin as part of PPROM latency abx. Cefuroxime had longer latency, fewer pos placental cultures, largely driven by less enterobacter, lower gram neg birth cultures. @MySMFM #SMFM23

[Anne Mardy, MD @annehmardy]

@astuebe @MySMFM Yes happy to already see 2 negative trials so far

[Anne Mardy, MD @annehmardy]

Another strike out for PTB prevention. RCT pessary for CL <20mm: 279 vs 263 controls. Stopped early for futility. Higher rates of neonatal death, similar IUFD. @MySMFM #SMFM23

[Anne Mardy, MD @annehmardy]

Of 1767 pts in a perinatal mental health clinic, 19% had high (>3) adverse childhood experiences (ACEs). 34% of these had suicidal ideation vs 13% <3 ACEs. aOR3.6 w dose response w each ACE. @EmilySMillerMD @MySMFM #SMFM23 #SMFM2023

[Anne Mardy, MD @annehmardy]

@HighRiskStork Yes! Thankful for a negative study…

[Anne Mardy, MD @annehmardy]

@HighRiskStork Not buying it…

[Anne Mardy, MD @annehmardy]

+THC exposed more SGA, IUFD, PIH, even after controlling for confounders (incl tobacco)

[Anne Mardy, MD @annehmardy]

Of >9,000 1st TM pregnancies in nuMoM2b group, 5.8% pos THC confirmed on mass spec @MySMFM #SMFM2023 @MetzTorri

[Anne Mardy, MD @annehmardy]

+THC had higher anxiety, +tobacco, opioids confirmed on mass spec

[Anne Mardy, MD @annehmardy]

Secondary analysis of CHAP trial: BP <130/80 vs >130/80 a/w decreased preeclampsia, preterm birth, neonatal morbidity without increasing SGA #mysmfm #SMFM2023

[ISUOG @ISUOG]

Systematic review and meta-analysis by Bet et al. published in #UOGJournal shows fetal premature atrial contractions are associated with a 4-5-fold increase in the risk of congenital heart defect compared with the general population https://t.co/Ygc6N63io8 #ISUOG @WileyHealth