Tom Appleton

🇨🇦 Rheumatologist, scientist, dad, he/him, advocate for #healthcare, #rheumatology, #research, #osteoarthritis. Tweets my own

[Osteoarthritis and Cartilage Journals @OACJournal]

🚨Standard scRNA-seq often excludes cells with high mitochondrial RNA content (pMT).🚨

Work by Tran et al. investigates how exclusion of high-pMT cells affects the transcriptional landscape of knee OA synovium and explores their role in disease.

🔗https://t.co/UV0hy7VYOA

[Healio Rheumatology @HealioRheum]

📢 “When we first started to see the big effects of these blockbuster #GLP1 drugs, people were talking about weight loss from Hollywood to regular people’s homes,” said Dr. Tom Appleton @appletonlab.

Read the Healio Exclusive @HealioRheum 👇

https://t.co/aGQzuTmlTW

[CRA SCR @CRASCRRheum]

🎙️NEW #AroundtheRheum podcast episode!

Co-hosts Drs. Daniel Ennis & @Janetbirdope chat with Dr. Sherry Rohekar about the new Canadian Living Guideline for the Management of Axial Spondyloarthritis!

You won't want to miss it!

Listen now🔈https://t.co/83HjOWGl2p

[Tom Appleton @appletonlab]

Oof 😓. 🇦🇺 AUS health demographics often parallels Canada 🇨🇦… not so great outlook. Intl. #osteoarthritis research community: let’s go! 📈

[Ilana Ackerman @IlanaAckerman]

Out now in @TheLancetRheum - our new arthritis projections for Australia

@ArthritisAust @Monash_SPHPM @RachelleBuchbin @danielleberko

➡️ 3.11 million people living with OA by 2040
➡️ almost $10 billion of health system expenditure for OA by 2040

[Tom Appleton @appletonlab]

Well said @ronjune2 this is helpful insight

[Ron June @ronjune2]

Wanted to add a bit about this paper...I learned a ton! First, there is some very good OA biomarker work out there, led by the Krauss Lab at Duke.

Also, almost 50% of the papers were papermill crap. Written with/exclusively by AI using public data and not contributing...

[Tom Appleton @appletonlab]

A total honour! You will all do great things in, and for the world. Science + medicine 💜🩺 🧬

[Western Schulich MD/PhD @Western_MDPhD]

Last week, we had the incredible opportunity to hear from Western MD/PhD alum & @CITAC_ACCFC co-founder Dr. Tom Appleton @appletonlab on all things clinician-scientist (no cap 😎) — from funding research to finding jobs, writing great grants #ABW, & balancing career & family 💡👏

[Tom Appleton @appletonlab]

Rheumy (the bear) and the Rheums! Our new band name! Jk, come see Rheumy at the ⁦@takeapaincheck⁩ booth at #ACR24

[Tom Appleton @appletonlab]

#nationaltreasure 🥇

[Cheryl Koehn @CherylKoehn]

@jrheum @ACEJointHealth Love @jrheum A constant in Canadian rheumatology since 1728! 😉🙌🏼 @CarterCartho @Janetbirdope @appletonlab @RheumNow @EsdaileJohn #ACR24 #jrheum

[Tom Appleton @appletonlab]

Should we be striving to prevent STD (synovial tissue damage) in #osteoarthritis trials? 📣

[Osteoarthritis and Cartilage Journals @OACJournal]

Interesting findings in this month's @OACJournal 🚨

Worse histopathological scores for synovial tissue damage is associated with more pain in late-stage knee OA ➡️

Free to read https://t.co/pERWH1qV4k

@HollyPhilpott14 @appletonlab @Path_Matt @WOBL_Western
⁩ ⁦

[Tom Appleton @appletonlab]

Inflammation is bad. What if synovial tissue damage is even worse? In our new study, ⁦@HollyPhilpott14⁩ and the #WOREO team discover a link between synovial tissue damage and worse OA pain. ⁦@WOBL_Western⁩ ⁦@westernuBJI⁩ ⁦@WesternU⁩ https://t.co/RKw9kNdReq

[Tom Appleton @appletonlab]

Check out the @CanRIO_Tweets website for info 📣 https://t.co/4e158hjDnQ

[Janet Pope @Janetbirdope]

#CanRio cohort meeting
#Rheumatologists involved in studying #ICi. #Check #point #inhibitors #immune #rheumatic #reactions

A fantastic year of #publications @CRASCRRheum 🇨🇦

[Tom Appleton @appletonlab]

Fun with the @CanRIO_Tweets team!

[Janet Pope @Janetbirdope]

Thanks to @NigilHaroon and @CRASCRRheum for sponsoring the members of
#Canadian #CanRio

▶️cohort on oncology Pts who have #rheumatic complications from #immune #checkpoint #inhibitors

A lovely dinner and #karaoke 🎤

#ICI 🇨🇦

Singing and dancing nearly surpasses research!

[Tom Appleton @appletonlab]

@NigilHaroon @CRASCRRheum @Janetbirdope @azbib @mcgill_mh @CanRIO_Tweets a great weekend!

[Tom Appleton @appletonlab]

Alright #MedTwitter What’s your differential for knee pain? Let’s do this! ⬇️ #osteoarthritis

[Rheum Cat @rheum_cat]

As part of our @oarsinews Early-stage symptomatic knee osteoarthritis (#EsSKOA) initiative:
Our goal is to identify common conditions considered in the differential diagnosis of #EsSKOA.

Take the survey here: https://t.co/7W7DhShDFM
Closes May 20, 2024

[Tom Appleton @appletonlab]

@SchulichMedDent @drsoup09 @STLHESAPES Amazing! Congratulations!

[Tom Appleton @appletonlab]

Got data? Join the effort! ⬇️📣

[Rheum Cat @rheum_cat]

The Early-stage Symptomatic Knee Osteoarthritis (EsSKOA) Initiative @oarsinewsis seeking datasets for analyses

Let us know if you have a dataset with >100 adults with knee symptoms & data on identified candidate items

https://t.co/q9rPmUCoBN

[Rheum Cat @rheum_cat]

The Early-stage Symptomatic Knee Osteoarthritis (EsSKOA) Initiative @oarsinewsis seeking datasets for analyses

Let us know if you have a dataset with >100 adults with knee symptoms & data on identified candidate items

https://t.co/q9rPmUCoBN

[Tom Appleton @appletonlab]

Go Frank! 🥂

[Silvia Penuela @DrSilviaPenuela]

Congratulations to the Distinguished University Professor Dr. Frank Beier. Great lecture and well deserved celebration 👏🏼 @BeierLab @westernuProvost @WesternU @SchulichMedDent @westernuPandP

[Tuhina Neogi, MD, PhD @Tuhina_Neogi]

Interested in helping the early-stage symptomatic knee #osteoarthritis (#EsSKOA) classification criteria development @OARSInews initiative?

Participate in this survey: https://t.co/i7z6Su5614

[Tom Appleton @appletonlab]

@curious_zan @OARSI_ECI @Harkey_MS @JesseCharlton_ @Knee_Howells @belinda_lawford @Andre_Dellisola @jwhittak_physio @Erin_Macri @CollJamie What a fun event! Great job by all the pitchers!