Arianna Sanders

Head of Product @AltoPharmacy. Passionate Supply Chain + Warehouse Dweeb. @Columbia Mid East Studies & Biz Mgmt.

I want to see your factory. 🏭

[Arianna Sanders @ariannasan]

Uber driver in SF this morning predicted Marco Rubio presidential run next cycle. Fascinating!

[Arianna Sanders @ariannasan]

@Brady_H Any idea of the difference in adaptation between men / women? I wonder because women tend to enjoy being in heat so much. 😅 (Sitting in the sun by pool, scalding hot shower / bath, etc)

I’m curious about the cardiac impact of heat perception.

[Arianna Sanders @ariannasan]

@juliachesky @MeganNyvold Fwiw I think engagement rings this large are so gauche. (And impractical)

There’s a time and place for a bozo huge lab diamond and IMO it’s for a * fun * piece of jewelry with personality.

[Arianna Sanders @ariannasan]

@juliachesky @MeganNyvold Yes, takes a small amount of additional searching to find the pricing that I mentioned. There will always be premium pricing for convenience / design, even if the product is a massive discount from the natural diamond.

[Arianna Sanders @ariannasan]

@juliachesky @MeganNyvold You can get an 8-10 carat lab diamond for $500 - $1000.

[Arianna Sanders @ariannasan]

@alt1na1 @MurrayHillGuy1 Oof, I would’ve immediately dumped any dude who suggested going to the psychic.

[Arianna Sanders @ariannasan]

@can Someone saw “Murat” and didn’t think he was Turkish? 🫪

[Arianna Sanders @ariannasan]

Why did every car manufacturer choose to replicate the worst feature of a Tesla?

The stupid flat “poke it to open” door handles!

[Arianna Sanders @ariannasan]

@jawwwn_ @MollySOShea @Gwynne_Shotwell @elonmusk She is so so so so so good at her job.

[Arianna Sanders @ariannasan]

@tolstoybb Didn’t realize I was in this club.

[Arianna Sanders @ariannasan]

@tenobrus @growing_daniel Don’t tell us to keep our hair long AND get mad when the drain gets clogged. What are we to do!

[Arianna Sanders @ariannasan]

@geofherb @powerbottomdad1 Minimum effective dose!!! Faster isn’t better keep with your slow steady schedule. You are doing just fine and probably don’t need to go higher than 4!

[Arianna Sanders @ariannasan]

@nisreenmandvi @bronzeageshawty You can get an AMH test ordered through your PCP. You don’t need function specifically for this test, function does a lot of other tests and great UI / context.

It’s great but not strictly necessary.

[Arianna Sanders @ariannasan]

@coldhealing Whewww spiritually empty fumes wafting off of the guy.

[Arianna Sanders @ariannasan]

@EntropicOtter @bronzeageshawty Big agree! Keep testing (especially given recent weight loss), add ApoB / Lp(a) to determine what the right next levers are.

In the meantime, keep exercising, swap some red meat out / fish in, eat fiber.

Eventually / maybe, explore a statin or PSK-9 inhibitor!

[Arianna Sanders @ariannasan]

@WesternScramasa @ecomjeg @maxmarchione Not entirely irrelevant!

If large body size is * because of * metabolic dysfunction — fixing it takes more intervention! But I’m with you that it’s not some simple / linear dosing scheme like X MG per Y lbs of body weight.

[Arianna Sanders @ariannasan]

@rabahrahil @maxmarchione These are obese subjects. You’re going to see a lot of muscle loss along with fat loss typically.

I’d be careful about trying to pull too much from these subject into your life. If you’re micro dosing, keep your protein intake high and keep doing the work in the gym! 💪

[Arianna Sanders @ariannasan]

@jons6111 @nogginnoticer @maxmarchione This is basically the right answer. There’s * a lot * of comorbidities for obesity. More accrued metabolic resistance takes more intervention to overcome.

It’s not only about appetite suppression but slowly working the whole system back to neutrality.

[Arianna Sanders @ariannasan]

@ecomjeg @maxmarchione Bigger bodies with more accrued metabolic resistance require more intervention to offset.

Everybody’s minimum effective dose and maximum tolerable dose will be different and may change over time!

Key is to start low, titrate, monitor closely!

[Arianna Sanders @ariannasan]

@Entro__py @KontraInvest @Gisele_ShoeSmug @maxmarchione Margin compression (even for brand drugs) is a reality but I still think the effectiveness data and extremely large market will mean we continue to see one blockbuster drug after the next in this area.