Alice Ruo Wei Tang

building things in precision oncology, brain tumor doctor, displaced European | @ImperialMed @HarvardNeuroMDs @DanaFarber

[Jason Sheltzer @JSheltzer]

AI is cool and all... but a new paper in @ScienceMagazine kind of figured out the origin of life?

The paper reports the discovery of a simple 45-nucleotide RNA molecule that can perfectly copy itself.

[Alex Cui @alexcdot]

Okay so, we just found that over 50 papers published at @Neurips 2025 have AI hallucinations

I don't think people realize how bad the slop is right now

It's not just that researchers from @GoogleDeepMind, @Meta, @MIT, @Cambridge_Uni are using AI - they allowed LLMs to generate hallucinations in their papers and didn't notice at all.

It's insane that these made it through peer review👇

[Alice Ruo Wei Tang @ARWTMD]

4: Grateful to the organizers and chairs for an outstanding forum bringing together medical oncologists, neurooncologists, radiation oncologists and neurosurgeons @BrainTumorDoc @PTarantinoMD @DrAMansouri @lungoncdoc @JAMouabbi @LauraAlderMD @Moranaaa

[Alice Ruo Wei Tang @ARWTMD]

1: 200k patients a year get the devastating news that their cancer has gone to their brain. While I was in medical school, they would have lived single digit months. Given the prognosis, trials often excluded the patients who needed them most.

[Alice Ruo Wei Tang @ARWTMD]

3: Big questions remain:
• Optimal sequencing
• Timing with SRS/RT
• Who benefits most?

The field is moving fast, and we urgently need consensus. In a heterogeneous population, the key questions we ask, data we collect and the way we design trials make all the difference.

[Paolo Tarantino @PTarantinoMD]

Amazing night (and photos)!

Here my reaction at @ARWTMD telling me that mojitos are finally back after a decade on the sidelines. Kinda like ADCs.

[Paolo Tarantino @PTarantinoMD]

Results from OptiTROP-B01 out in @NatureMedicine. The TROP2-ADC sacituzumab tirumotecan improved PFS and OS in highly pretreated mTNBC, irrespective of Trop2 exp. Results similar to ASCENT. Approved in China, may soon also reach the west (4th topo1 ADC). https://t.co/0pXSYd0uxl

[Alice Ruo Wei Tang @ARWTMD]

3/ Being in DC for AI+Biotechnology demonstrated that bio touches everything—defense, agriculture, supply chains.

The National Security Commission on Emerging Biotech is clear: biotech is now a core pillar of US national strategy

https://t.co/chGIw7mXOc

[Alice Ruo Wei Tang @ARWTMD]

1/ What if biotechnology decides the next global superpower?

Senators @AlexPadilla4CA @SenToddYoung introduced the National Biotechnology Initiative Act of 2025, recommending the US puts $15B on the table to accelerate breakthroughs

Meanwhile, the global balance is shifting.

[Alice Ruo Wei Tang @ARWTMD]

2/ In 2019, China’s biotech market was <10% the size of the US.

Today?

1 in 2 industrial robots is installed in China, with a 400-fold increase in biopharma R&D spending, over the past decade. China is racing ahead in novel modalities like ADCs and T-cell engagers

[U.S. FDA @FDA]

Today, the FDA is taking a groundbreaking step to advance public health by replacing animal testing in the development of monoclonal antibody therapies and other drugs with more effective, human-relevant methods.
https://t.co/m8vsOah6qx

[Alice Ruo Wei Tang @ARWTMD]

The neurologist will see you now 🧠 congratulations to the newly minted Harvard Neurology Class of 2024! Thanks to everyone who was woken up by an aberrant page, waited for us as we left the hospital late (again), and supported us through this journey @harvardneuromds

[Alice Ruo Wei Tang @ARWTMD]

Final shift of residency ✅ thanks @harvardneuromds for the last four years (!) of training, friendship and excellent neurology. Next stop: @MGHNeuroOnc @DanaFarber 🧠

[Alice Ruo Wei Tang @ARWTMD]

Dearly beloved, we are gathered here today to get through this thing called “life”

Happy hour with @harvardneuromds Natalia @nsanar (and Prince)! @Marinos_S @AnsonWang_

[Neurology Journal @GreenJournal]

Neurology Podcast: Drs. Justin Abbatemarco and Alice Tang discuss the association between immune status and herpes simplex virus encephalitis. Listen now: https://t.co/rC99aOIwkl
Read the related article in Neurology: https://t.co/xjWLL0fk08
#NeuroTwitter @ARWTMD @JRAbbatemarco

[Alice Ruo Wei Tang @ARWTMD]

We found the HSVE population had higher rates of medical comorbidities and was strongly associated with preexisting autoimmune disease and exposure to immune suppressing medications.

[Alice Ruo Wei Tang @ARWTMD]

Excited to share our new study on HSV encephalitis in patients with autoimmune conditions! https://t.co/jytYbPEwRX @GreenJournal @harvardneuromds @BWHNeurology @MGHNeurology @shamik_b

[Alice Ruo Wei Tang @ARWTMD]

Immunocompromised patients may present with atypical symptoms, without a CSF pleocytosis, and with a false-negative PCR.