☣️ This spanner with a hemoperfusion cartridge helped saving a patient with refractory status epilepticus with suspected unknown drug intoxication.
🕵️♂️ Let's find out more about the case !!!
Recognition of one's work is surely gratifying and encourages to persevere !!!
Amar Gandhi Foundation Award (2015) as a resident to Susruta Award (2024) as a consultant.
Thank you 🙏
@drnileshagrawal@MaxHealthcare@AshayShingare@JaslokHospital_
🎨This painting by Sir Roy Calne, British Transplant surgeon depicts Easter Island/Rapa Nui where the moai statue expounding to other 5 moai is the erudite son of India-Dr Surendranath Sehgal and the molecule is rapamycin or Sirolimus
found in the soil of the island.
#ISOT2024
Implications: If leukopenia occurs after starting above drugs, check for NUDT15 variants, especially in Asian patients.
Study authors:
M M Bahadur @MMBahadur
Nikhil Dhope @DhopeNikhil
Rejitha R Kaimal @DrRejithaKaimal
& myself @AshayShingare
https://t.co/eFMkEHARwD
Our study shows kidney transplant recipients with NUDT15 genetic variation are at increased risk of early onset (<60 days) leukopenia and severe leukopenia after starting valganciclovir.
Glad to share that our study at Jaslok Hospital, Mumbai on valganciclovir induced leukopenia in kidney transplant pts with NUDT15 mutation published in Kidney International Reports.
Thanks to Dr @MMBahadur sir and Dr @AshayShingare sir
@DrRejithaKaimal
https://t.co/Sl0QPAVGjv
A very interesting talk by Dr Madan Bahadur on NUDT15 and drug interaction with ganciclovir (and azathioprine), at the #ISOT2023 causing severe leucopenia. He talked about giving ganciclovir (for Rx of proven CMV infection) once in 4 days in such pts.