Alisha S M Hall

PhD fellow in psychiatric genetics @Aarhusuni (🇩🇰💃🇩🇪🇺🇸)
#epidemiology #psychology #psychiatry #chronicdisease

[PGC Consortium @PGCgenetics]

1/n Our multi-ancestry #GWAS meta-analysis of major depression is now published in @CellCellPress.

https://t.co/5ZtpbzKLpx

A thread 🧵:

[Doug Speed @dougthespeed]

I am advertising for a postdoc in statistical genetics (Aarhus University). Application deadline is 31st January. The position is linked to the ERC-funded project on statistical methods for classifying diseases. Please see https://t.co/8xgB315Svh for more details.

[Andrew McIntosh @mcintosh2001]

Fascinating paper on the genetics of people with a diagnosis of borderline personality disorder https://t.co/xrEkioW4wA

[Dr Ellie Murray, ScD @EpiEllie]

A “nocebo effect” is just a harmful “placebo effect”, but most people don’t even understand what a placebo effect is.

Placebo and nocebo effects are NOT simply change over time. And they definitely can’t be measures via ~vibes~.

Read more: https://t.co/aiWXoZ6T9V

[Alisha S M Hall @AsmHall]

@f_streit @BBRFoundation @stephanripke @zi_mannheim Congratulations / Herzlichen Glückwunsch! I look forward to hearing all about the cool projects you have planned at the WCPG :)

[Abdel Abdellaoui @dr_appie]

My talk at Genomics of Brain Disorders #GBD2023 titled:

Genes influence complex traits through environments that vary between geographic regions 🧬🗺️

I talk about using genetic data to reveal how society makes genetic effects seem stronger through our socio-economic system 💰

[Alisha S M Hall @AsmHall]

Also, the suggestion to get started on data collection for epigenome-wide studies that capture regional differences sounded interesting.

Many potential applications in epidemiology, not just brain disorders. I wonder how one could go about this @uk_biobank?

[Alisha S M Hall @AsmHall]

Take-home message of @dr_appie's talk at #GBD23 for our research: We as a society make genetic effects stronger, giving individuals a double advantage or double disadvantage. This inequality is increasing over time.

I feel like I need to be reminded of this more often.

[Alisha S M Hall @AsmHall]

Talk by @oleaandreassen at #GBD23 has convinced me: MiXeR needs to be part of my upcoming post-GWAS analyses. These Venn diagrams of overlapping variants between disorders are very intuitive.

[Alisha S M Hall @AsmHall]

Good reminder by Elise Robinson to think 3D when interpreting genetic findings.

DNA folds in an incredibly complex and consistent way--gene density and degree of intrachromosomal contact could help explain how genetic variation at 1 locus effects nearby gene expression. #GBD23

[Alisha S M Hall @AsmHall]

Short tandem repeat (STR) expansion disorders play a role in diseases like #Huntingtons, with repeat length linked to earlier disease onset. STR make up 3% of the human genome & can be measured with WGS. Super interesting talk by Ariana Tucci about germline instability at #GBD23!

[Alisha S M Hall @AsmHall]

Super cool to hear Sonia Gandhi talk about how genetic findings for #ParkinsonsDisease informed proteinopathy research in different microglia at #gbd23. Coming from psychiatry research, it's interesting to hear what neurodegeneration researchers are doing.

[Jeff Gilchrist @jeffgilchrist]

How #respirators actually work and which type is best?

I see many claims #masks don't work. This thread will explain *how* they block #viruses much smaller than the size of the holes in the #filter and why you can still smell nasty things while wearing effective masks. 🧵1/

[Dr. Glaucomflecken @DGlaucomflecken]

Infectious disease goes on a hike

[World Health Organization (WHO) @WHO]

4.5 TRILLION CIGARETTES are discarded per year worldwide, making them the most littered item on 🌎🌍🌏

What is inside a cigarette? Let’s find out 🔬

#TobaccoExposed 🚭

[Alisha S M Hall @AsmHall]

@kareem_carr @MartinaNurasyid @AnnekathrinLudt The answers on here sound a bit like your conversation a while ago...

[Eric Topol @EricTopol]

Should I get a 2nd booster?
A much more difficult decision than the 1st booster.
Review of the data and my recommendations
https://t.co/Ni6O3Dux8L

[Alisha S M Hall @AsmHall]

@f_streit I am amazed and horrified at the same time.

[Eric Topol @EricTopol]

With an infographic